The liver's production of glucose is a problem for me. I'm a type II diabetic/very insulin resistant, 57 YO woman. My blood sugar is always much higher in the morning than the night before (not uncommon among type IIs) and it is the result of my liver pumping out more sugar even though my blood sugar is nowhere near low. It is certainly one important factor, but not the only one, in my current state of turtlehood.