I'm a bit torn on the hfcs vs. sucrose thing. On the one hand it might be prudent to be wary of the great increase in free fructose vs. fructose bound as sucrose in the diet, that seems more likely to be a big deal to me than the small increase in percent fructose. On the other hand, trust sugar itself seems horribly imprudent to me, I shuddered a while back when I saw people hoping to improve their health by getting coke made with sucrose from Mexico.

The canary in the coal mine Pima Indians got in trouble just fine with plain old sugar.