It totally makes sense to me. (non scientist, just based on personal experience and limited science understanding). When I did low fat years ago, my fat intake was way less than 30 percent.... and I was superfit and healthy and thin EXCEPT that the deprivation and cravings made me crazy. In other words, from a metabolic/weight standpoint, low fat worked. it just wasn't sustainable.

In the "moderation" class, you "moderate everything" -- and it's the road to hell. You have BOTH the insulin issues of the baked potato and grains upping your glucose, AND the calorie issues of the high fat. That's why (in my opinion only) "moderation" doesn't work -- it gives you the worst of both worlds.

Then you get into the high-fat area, and you lose the appetite and sugar craving effects of the insulin, and go back to a beneficial metabolism.

That may be a simplistic summary, but it certainly explains my experience. Moderation = death to diet.