I don't know if this is quite what you're looking for but I just discovered that in people with weak adrenals dhea supplements are known to convert directly to estrogen, rather than do all the other stuff it is supposed to. This often leads to estrogen dominance, which can cause all kinds of weight gains.

It's also important to watch for food allergy reactions. I'm up 15 lbs because cortef is made with cornstarch and I didn't realize it until I was completely miserable. I hope most of that will go away as my body clears out the inflammation.