Haven't read this one yet--but one thing that pops out, mice that have gained a bit of fat one week on a more fattening diet (which includes a ketogenic diet, for these mice, and this diet) will under-eat low fat chow for a while, so this is an intermittent calorie restriction study as well as an intermittent ketogenic diet study.



One thing Taubes wrote about in GCBC is food texture's effect on food intake by rodents. Hard, low fat pellets are less pleasant, can make the animal's mouths sore, adding more water or fat makes for a more pleasant eating experience. Sort of a flip-side for hedonic eating. Are they eating more fatty chow because it's more pleasing? Or less low fat chow because it's particularly unpleasant, only worth eating past a certain point out of necessity?

Also says Crisco changed their formula on them mid-study, shorter chain fats, so the fatty diets got mushier, they subbed some cocoa butter out for Crisco to get the right consistency. But did nothing towards matching consistency between the control diet and the fatty diets.