Sun, Feb-01-09, 08:50
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Senior Member
Posts: 15,075
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Plan: mostly milkfat
Stats: 190/152.4/154
BF:
Progress: 104%
Location: Ontario
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This metformin study references some diabetic methylglyoxal numbers versus non diabetic.
metformin study
" MG levels were significantly reduced by high-dosage (1,500-2,500 mg/day) metformin (158.4 +/- 44.2 nmol/l) compared with nonmetformin (189.3 +/- 38.7 nmol/l, P = 0.03) or low-dosage (< or = 1,000 mg/day) metformin (210.98 +/- 51.0 nmol/l, P = 0.001), even though the groups had similar glycemic control."
Methylglyoxal is measured in nanomoles (billionths of a mole.) Blood glucose, in contrast, is measured in millimoles (thousandths).
40000 x 210/1 000 000 000=8.4/1000
I just wanted to see what forty thousand times as reactive as glucose would mean. I don't really know from moles, but I understand that 8.4 is rather a high blood sugar. I guess if a person's MG level went this high because of a very very very low carb diet, but their blood sugar normalized, you'd have to balance the damage from the MG with the lessened damage from the change in blood glucose.
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