yeh me to i hav been on anti depressants for just over a year and i thnik iv been depressed all my life for other reasons then the low moods that PCOS gives, but the side affects realy get ya dwn, ur ment to exercise to help lose weight on metformin as everyone says it works wonders, but how can u even feel like exercisin wen ur sufferin all the stomach cramps and fatigue and have so little energy. i dont think that im gona lose any weight on it, i feel like iv put there 3 kilos i lost back on