View Single Post
  #4   ^
Old Sun, Aug-06-17, 17:47
M Levac M Levac is offline
Senior Member
Posts: 6,498
 
Plan: VLC, mostly meat
Stats: 202/200/165 Male 5' 7"
BF:
Progress: 5%
Location: Montreal, Quebec, Canada
Default

Quote:
Their study, published in Cell Metabolism today, shows that after a meal the brain responds to circulating insulin, which is increased after a rise in blood glucose. The brain then sends signals to promote the browning of fat to expend energy. By contrast, after a fast, the brain instructs these browned adipocytes to once more convert into white adipocytes, storing energy.

No.
Quote:
"What happens in the context of obesity is that the switch stays on all the time -- it doesn't turn on off during feeding," lead researcher Professor Tony Tiganis said.

No.

If eating (therefore insulin) causes browning (therefore greater Eout) then how is obesity created in the first place, when obesity is said to be created by more eating (therefore more insulin, therefore more browing, therefore more greater Eout)? See what I mean by "No."?

I'd like to cite diabetes type 1, where there's no insulin, there's hyperphagia, and there's emaciation. Hyperphagia therefore expected insulin, but no insulin because diabetes type 1 therefore no browing, yet no fat accumulation. Pfft, go to hospital, diagnose, treat, inject insulin, voila - fat accumulation. Be not-smart, inject insulin in same spot for years, voila - localized excess fat accumulation in a process called insulin-induced lipohypertrophy. Eat more carbs, inject more insulin (because eat more carbs - insulin dose depends on carbs, you see), voila - more fat accumulation all over the place. Incidentally, when that happens, the insulin-induced lipohypertrophy becomes invisible due to the amount of fat everywhere. This suggests that insulin-induced lipohypertrophy is also a system-wide phenomenon rather than just localized to the injection site(s). Anyways, the whole thing contradicts the idea that insulin somehow causes adipocytes to go brown after a meal.

Finally, biology doesn't waste for no reason. If there's excess energy, it will be used, not merely disposed.
Reply With Quote