I see this is an old topic. I'd love to hear from other members. I have PCOS, and was on metformin for years. I know that the one time I did low-carb in the past, it instantly solved the having-no-periods problem. That was amazing. But then I went on metformin and forgot low-carb. Now I'm on low-carb and am no longer taking metformin. I no longer have a uterus, so it's hard to tell what the effects on PCOS are at this stage. Is anyone else dropping metformin because being low-carb ?

Weirdly, no one has actually ever measured "insulin resistance" in me, the PCOS is probably genetic and certainly uncurable, but certainly low-carb is a must for me.