This ignores the fact that many, many people do not eat because they are hungry, but for taste and pleasure. Even when entirely full, they may stuff in another cookie or doughnut.
Not feeling hungry sure helps, as we low carbers have discovered without the help of vaccines. Some people do not even do well with stomach banding op's because they sabotage it by consuming too much sugar in liquid form.

And what about all those folks who are obese due to extreme insulin sensitivity or other hormonal issues...who are strict about low carbing and so on and still don't lose? Making them feel not-hungry will not make any difference to weight loss for them.

Val