Anecdotal n=1 (me) -- I must drink enough WATER daily or I get horribly debilitating cramps in my calves. I have to balance getting up once or twice in the night to pee, or being up for hours stomping around trying to get the calves to untie. three litres per day or else. And not all in the morning, some in the later afternoon (hence the getting up to pee). I do all the potassium, magnesium, etc, but without the straight water .....ooooeeee!