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Old Fri, Jan-19-18, 07:45
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teaser teaser is offline
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Posts: 15,075
 
Plan: mostly milkfat
Stats: 190/152.4/154 Male 67inches
BF:
Progress: 104%
Location: Ontario
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Mrs. C--yes. Obviously more to it than alcohol inevitably making people fatter. There's often a difference in the effect of a substance on rodents, depending on how they're exposed to it, I think it's likely that similar things happen in humans. If you take msg, for instance-- there are studies where it's fattening, and other studies where it seems to do the opposite. Added to the animal's food vs. the animal's water supply makes a difference. Maybe in that case it's a matter of the animals eating the food or drinking the water to get a sort of msg "fix."

I spotted this, relevant to skinny alcoholics, on another forum;

Quote:
This is something I've noticed for years. Visit any liquor store in most big cities and you see crowd of obvious alcoholics asking for money to fund their next beer or liquor purchase. They're almost always skinny.

Obviously, that's not a gauge of health as most probably have fatty liver disease.

However, alcohol is pretty dense in calories and many of these are drinking liters of the stuff daily. This is not cocaine we're talking about, which doesn't have calories.

My only guess is that they're obviously drinking their sustenance only and probably rarely eating solid foods, but this seems to be exception of the calories are the only thing that matters theory. Again, is alcohol very calorie dense.

Another theory is that the body doesn't convert alcohol to adipose tissue well. If you're recreational drinker a weekend bender may also leave you eating greasy food. Bar food is also extremely fattening, but hardcore alcoholics don't want to spend their funds on greasy food.

Anyone else notice this and wonder why this is common?


In Good Calories Bad Calories Gary Taubes wrote about glycerol as a possible rate limiting step for getting fat. The idea was that glycerol, as product of glucose breakdown, could be in too short supply to sustain fat storage on a low carb diet. We can make glycerol from protein, so that wasn't quite true. In the case of alcohol, it seems more likely, though. You can make fatty acids from alcohol, but probably very little glycerol or glucose. Maybe there's some explanation in there for why alcohol makes people hungrier, when it does, fat synthesis gives us another option besides oxidation for disposal of alcohol.


Quote:
Effects of fructose and other substances on ethanol and acetaldehyde metabolism in man.
Rawat AK.
Abstract
The comparative effectiveness of oral administration of fructose, glucose sucrose and alanine has been investigated on the rates of blood alcohol clearance, and acetaldehyde removal in man. Oral administration of fructose was found to exert the most pronounced effect. It increased the rate of blood alcohol clearance by about 100%. Orally administered alanine was found to be least effective in increasing the rate of blood alcohol clearance after blood alcohol had reached peak levels, perhaps due that poor absorption of alanine. Fructose administration partially prevented the ethanol-mediated increase in lactate/pyruvate and beta-hydroxybutyrate/acetoacetate in the blood. Fructose exerted the most pronounced antiketogenic effect and the levels of circulating free fatty acids decreased in the 24-hour fasted patients upon administration of fructose with ethanol compared to ethanol alone. Oral administrations of fructose, glucose, sucrose or alanine did not significantly change the levels of acetaldehyde in the blood. Combined administration of fructose with ethanol resulted in an increase in the levels of blood sorbitol. The mechanism through which fructose exerts its stimulatory effect on the metabolism of ethanol in the liver has been discussed.
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