hmmm so no real changes with anxiety for 5 htp? I'm kinda more interested in that supplement compared to st john's wort. Anyhow I live in the bay area of california and i'm kinda interested about the duke hospital thing. I've been having an ofly hard time finding a good psychiatrist that has time for me or who specializes in teens. Before my doctor moved to Europe I remember I asked her about an alternative for Paxil. I asked her about St John's wort and she didn't seem to like it very much. She told me that since paxil was working well for me but at a high dose then St john's wort will not help much because it's much much milder. She suggusted another supplement similar to st john's wort that she claims is stronger and better but I don't remember the name! It sounded so complex... do you suppose she was refering to 5 htp or some other supplement?