Maiden
Sun, Sep-08-02, 23:56
P-L-E-A-S-E - D-O - N-O-T - F-E-E-D - T-H-E - T-R-O-L-L
My blood chemistry isn't found in the textbook. What
might I have?
My calcium levels are on the high end (ranging between
9.8 & 10.4)
Yet Merck states that when serum calcium is *low*, that's when
osteomalacia (vitamin d deficiency) should be suspected.
This is inconsistent with my blood chemistry which indicates:
low 25-hydroxy D3 (23 ng/mL) - indicative of Vitamin D
deficiency, yet: *high* serum calcium (range 9.8 to 10.4)
I also have high bilirubin (1.6) and Merck states
(http://www.merck.com/pubs/mm_geriatrics/sec7/ch49.htm):
"Impairment of conversion to 25-hydroxy D3 occurs in patients
with severe liver disease...
So for all I know, perhaps the only way I'd absorb Vitamin D
is via calcidiol, which (according to Merck) is better
absorbed than ordinary Vitamin D & bypasses any defect in
25-hydroxylation in liver.
But the question remains: If Merck is correct, then why do I
have *high* calcium, if I have such low Vitamin D? Actually, I
don't quite understand Merck's reasoning, because it seems to
me that if Vitamin D deficiency causes poor calcium
absorption, this would cause calcium to remain in the
bloodstream, instead of binding to bone, and therefore should
cause *high* serum calcium levels.
My blood chemistry isn't found in the textbook. What
might I have?
My calcium levels are on the high end (ranging between
9.8 & 10.4)
Yet Merck states that when serum calcium is *low*, that's when
osteomalacia (vitamin d deficiency) should be suspected.
This is inconsistent with my blood chemistry which indicates:
low 25-hydroxy D3 (23 ng/mL) - indicative of Vitamin D
deficiency, yet: *high* serum calcium (range 9.8 to 10.4)
I also have high bilirubin (1.6) and Merck states
(http://www.merck.com/pubs/mm_geriatrics/sec7/ch49.htm):
"Impairment of conversion to 25-hydroxy D3 occurs in patients
with severe liver disease...
So for all I know, perhaps the only way I'd absorb Vitamin D
is via calcidiol, which (according to Merck) is better
absorbed than ordinary Vitamin D & bypasses any defect in
25-hydroxylation in liver.
But the question remains: If Merck is correct, then why do I
have *high* calcium, if I have such low Vitamin D? Actually, I
don't quite understand Merck's reasoning, because it seems to
me that if Vitamin D deficiency causes poor calcium
absorption, this would cause calcium to remain in the
bloodstream, instead of binding to bone, and therefore should
cause *high* serum calcium levels.