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Ironjustic
Mon, May-26-08, 17:16
They've decided to NOT raise the cabin pressure .. Not enough
evidence .. They aren't counting the db's .. just the cash ..
Reminds me of the water heaters which had the 'defect' .. they
decided it was "cheaper" to pay off the explosions and
screaming deaths than to recall.
"8000 ft has been accepted as the maximum operational cabin
pressure altitude in the airline industry."
"On the basis of our findings, we conclude that maintaining a
cabin altitude of 6,000 feet or lower (equivalent to a
barometric pressure of 609 mm Hg or higher) on long-duration
commercial flights will reduce the discomfort among
passengers,"
Cabin cruising altitudes for regular transport aircraft.
[Journal Article] Aviat Space Environ Med 2008 Apr;
79(4):433-9.
The adverse physiological effects of flight, caused by ascent
to altitude and its associated reduction in barometric
pressure, have been known since the first manned balloon
flights in the 19th century. It soon became apparent that the
way to protect the occupant of an aircraft from the effects
of ascent to altitude was to enclose either the individual,
or the cabin, in a sealed or pressurized environment. Of
primary concern in commercial airline transport operations is
the selection of a suitable cabin pressurization schedule
that assures adequate oxygen partial pressures for all
intended occupants. For the past several decades, 8000 ft has
been accepted as the maximum operational cabin pressure
altitude in the airline industry. More recent research
findings on the physiological and psycho- physiological
effects of mild hypoxia have provided cause for renewed
discussion of the "acceptability" of a maximum cabin cruise
altitude of 8000 ft; however, we did not find sufficient
scientific data to recommend a change in the cabin altitude
of transport category aircraft. The Aerospace Medical
Association (AsMA) should support further research to
evaluate the safety, performance and comfort of occupants at
altitudes between 5000 and 10,000 ft.
Aviation, space, and environmental medicine [Aviat Space
Environ Med]
--------------------------------------------------------------
-------------------
Long flights cause altitude sickness 6 Jul 2007, 0002 hrs
IST,REUTERS
BOSTON: Feeling a little achy, light headed or short of breath
on a long plane flight? A new study suggests you might be
suffering from a mild form of altitude sickness.
Until now, such symptoms had been attributed to jet lag,
dehydration, air contamination or being stuck in a cramped
seat for hours.
Researchers report that true altitude sickness - with its
nausea, vomiting and sleep disturbances - was no more likely
in volunteers in simulated airplane cabins where the pressure
was equivalent to 8,000 feet above sea level than it was when
the pressure was closer to sea level.
But after three hours of exposure to cabin pressures
equivalent to 7,000 to 8,000 feet, the simulated fliers were
more likely than others to report backaches, headaches,
shortness of breath, light- headedness and impaired
coordination.
Women and younger people were the most likely to experience
symptoms. "On the basis of our findings, we conclude that
maintaining a cabin altitude of 6,000 feet or lower
(equivalent to a barometric pressure of 609 mm Hg or higher)
on long-duration commercial flights will reduce the discomfort
among passengers," wrote Michael Muhm and colleagues.
-----------------------------------
Briefs: Flying may pose risk to sleep apnea sufferers By Times
Staff, Wires In print: Friday, May 23, 2008
Flying may pose risk to sleep apnea sufferers
People with severe obstructive sleep apnea (OSA) taking
airline flights may have a greater risk from cardiac stress
than healthy people, according to new research. The scientists
compared oxygen levels and breathing by simulating flight
conditions. "It is normal for the rate of breathing to
increase when air pressure falls,'' said Leigh Seccombe, an
Australian scientist. "We found that (for those with OSA),
their breathing intensity increases at about the same rate as
it does in healthy people." But the physiological stress and
demand for oxygen was increased in people with OSA. "The work
they do to run the core range of body functions (heart, lungs,
brain) is much greater under cabin conditions.''
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
Ironjustic
Wed, May-28-08, 17:16
On May 26, 10:34=A0am, ironjustice <ironjust...@cashette.com>
wrote: thrombosis <<
People are still under the assumption it is the cramped
seating conditions which causes thrombosis ..
It's not ..
Vol. 119, No. 3, 2008 ----------------------------------------
-------------------------------------=
----
Review
Altitude and Coagulation Activation: Does Going High Provoke
Thrombosis?
J.J. van Veena, M. Makrisb
aLeicester Haemophilia Comprehensive Care Centre and
Haemostasis and Thrombosis Unit, Leicester , and bSheffield
Haemophilia and Thrombosis Centre, Sheffield, UK
Address of Corresponding Author
Acta Haematol 2008;119:156-157 (DOI: 10.1159/000128045)
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
> They've decided to NOT raise the cabin pressure .. Not
> enough evidence .. They aren't counting the db's .. just
> the cash ..
>
> Reminds me of the water heaters which had the 'defect' ..
> they decided it was "cheaper" to pay off the explosions and
> screaming deaths than to recall.
>
> "8000 ft has been accepted as the maximum operational cabin
> pressure altitude in the airline industry."
>
> "On the basis of our findings, we conclude that maintaining
> a cabin altitude of 6,000 feet or lower (equivalent to a
> barometric pressure of 609 mm Hg or higher) on long-duration
> commercial flights will reduce the discomfort among
> passengers,"
>
> Cabin cruising altitudes for regular transport aircraft.
> [Journal Article] Aviat Space Environ Med 2008 Apr;
> 79(4):433-9.
>
> The adverse physiological effects of flight, caused by
> ascent to altitude and its associated reduction in
> barometric pressure, have been known since the first manned
> balloon flights in the 19th century. It soon became apparent
> that the way to protect the occupant of an aircraft from the
> effects of ascent to altitude was to enclose either the
> individual, or the cabin, in a sealed or pressurized
> environment. Of primary concern in commercial airline
> transport operations is the selection of a suitable cabin
> pressurization schedule that assures adequate oxygen partial
> pressures for all intended occupants. For the past several
> decades, 8000 ft has been accepted as the maximum
> operational cabin pressure altitude in the airline industry.
> More recent research findings on the physiological and
> psycho- physiological effects of mild hypoxia have provided
> cause for renewed discussion of the "acceptability" of a
> maximum cabin cruise altitude of 8000 ft; however, we did
> not find sufficient scientific data to recommend a change in
> the cabin altitude of transport category aircraft. The
> Aerospace Medical Association (AsMA) should support further
> research to evaluate the safety, performance and comfort of
> occupants at altitudes between 5000 and 10,000 ft.
>
> Aviation, space, and environmental medicine [Aviat Space
> Environ Med] -----------------------------------------------
> ----------------------------=
-=AD-----
>
> Long flights cause altitude sickness 6 Jul 2007, 0002 hrs
> IST,REUTERS
>
> BOSTON: Feeling a little achy, light headed or short of
> breath on a long plane flight? A new study suggests you
> might be suffering from a mild form of altitude sickness.
>
> Until now, such symptoms had been attributed to jet lag,
> dehydration, air contamination or being stuck in a cramped
> seat for hours.
>
> Researchers report that true altitude sickness - with its
> nausea, vomiting and sleep disturbances - was no more likely
> in volunteers in simulated airplane cabins where the
> pressure was equivalent to 8,000 feet above sea level than
> it was when the pressure was closer to sea level.
>
> But after three hours of exposure to cabin pressures
> equivalent to 7,000 to 8,000 feet, the simulated fliers were
> more likely than others to report backaches, headaches,
> shortness of breath, light- headedness and impaired
> coordination.
>
> Women and younger people were the most likely to experience
> symptoms. "On the basis of our findings, we conclude that
> maintaining a cabin altitude of 6,000 feet or lower
> (equivalent to a barometric pressure of 609 mm Hg or higher)
> on long-duration commercial flights will reduce the
> discomfort among passengers," wrote Michael Muhm and
> colleagues.
>
> -----------------------------------
>
> Briefs: Flying may pose risk to sleep apnea sufferers By
> Times Staff, Wires In print: Friday, May 23, 2008
>
> Flying may pose risk to sleep apnea sufferers
>
> People with severe obstructive sleep apnea (OSA) taking
> airline flights may have a greater risk from cardiac stress
> than healthy people, according to new research. The
> scientists compared oxygen levels and breathing by
> simulating flight conditions. "It is normal for the rate of
> breathing to increase when air pressure falls,'' said Leigh
> Seccombe, an Australian scientist. "We found that (for those
> with OSA), their breathing intensity increases at about the
> same rate as it does in healthy people." But the
> physiological stress and demand for oxygen was increased in
> people with OSA. "The work they do to run the core range of
> body functions (heart, lungs, brain) is much greater under
> cabin conditions.''
>
> Who loves ya. Tom
>
> Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> =A0DEAD PEOPLE WALKING =A0http://tinyurl.com/zk9fk
Ironjustic
Wed, May-28-08, 17:16
On May 28, 8:13=A0am, ironjustice <teamtan...@hotmail.com>
wrote:thrombosis <<
Predisposed to thrombosis through .. too many red blood cell /
erythrocytosis .. polycythemia ..
"The patient with cerebral venous thrombosis described by
Fujimaki et al3 was severely polycythemic."
http://tinyurl.com/6q7t8c
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
> On May 26, 10:34=A0am, ironjustice
> <ironjust...@cashette.com> wrote: thrombosis <<
>
> People are still under the assumption it is the cramped
> seating conditions which causes thrombosis ..
>
> It's not ..
>
> Vol. 119, No. 3, 2008 --------------------------------------
> -------------------------------------=
-=AD-----
>
> Review
>
> Altitude and Coagulation Activation: Does Going High Provoke
> Thrombosis?
> J.J. van Veena, M. Makrisb
>
> aLeicester Haemophilia Comprehensive Care Centre and
> Haemostasis and Thrombosis Unit, Leicester , and bSheffield
> Haemophilia and Thrombosis Centre, Sheffield, UK
>
> Address of Corresponding Author
>
> Acta Haematol 2008;119:156-157 (DOI: 10.1159/000128045)
>
> Who loves ya. Tom
>
> Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> =A0DEAD PEOPLE WALKING =A0http://tinyurl.com/zk9fk
>
>
>
> > They've decided to NOT raise the cabin pressure .. Not
> > enough evidence .. They aren't counting the db's .. just
> > the cash ..
>
> > Reminds me of the water heaters which had the 'defect' ..
> > they decided it was "cheaper" to pay off the explosions
> > and screaming deaths than to recall.
>
> > "8000 ft has been accepted as the maximum operational
> > cabin pressure altitude in the airline industry."
>
> > "On the basis of our findings, we conclude that
> > maintaining a cabin altitude of 6,000 feet or lower
> > (equivalent to a barometric pressure of 609 mm Hg or
> > higher) on long-duration commercial flights will reduce
> > the discomfort among passengers,"
>
> > Cabin cruising altitudes for regular transport aircraft.
> > [Journal Article] Aviat Space Environ Med 2008 Apr;
> > 79(4):433-9.
>
> > The adverse physiological effects of flight, caused by
> > ascent to altitude and its associated reduction in
> > barometric pressure, have been known since the first
> > manned balloon flights in the 19th century. It soon
> > became apparent that the way to protect the occupant of
> > an aircraft from the effects of ascent to altitude was
> > to enclose either the individual, or the cabin, in a
> > sealed or pressurized environment. Of primary concern in
> > commercial airline transport operations is the selection
> > of a suitable cabin pressurization schedule that assures
> > adequate oxygen partial pressures for all intended
> > occupants. For the past several decades, 8000 ft has
> > been accepted as the maximum operational cabin pressure
> > altitude in the airline industry. More recent research
> > findings on the physiological and psycho- physiological
> > effects of mild hypoxia have provided cause for renewed
> > discussion of the "acceptability" of a maximum cabin
> > cruise altitude of 8000 ft; however, we did not find
> > sufficient scientific data to recommend a change in the
> > cabin altitude of transport category aircraft. The
> > Aerospace Medical Association (AsMA) should support
> > further research to evaluate the safety, performance and
> > comfort of occupants at altitudes between 5000 and
> > 10,000 ft.
>
> > Aviation, space, and environmental medicine [Aviat Space
> > Environ Med] ---------------------------------------------
> > ----------------------------=
---=AD=AD-----
>
> > Long flights cause altitude sickness 6 Jul 2007, 0002 hrs
> > IST,REUTERS
>
> > BOSTON: Feeling a little achy, light headed or short of
> > breath on a long plane flight? A new study suggests you
> > might be suffering from a mild form of altitude sickness.
>
> > Until now, such symptoms had been attributed to jet lag,
> > dehydration, air contamination or being stuck in a cramped
> > seat for hours.
>
> > Researchers report that true altitude sickness - with its
> > nausea, vomiting and sleep disturbances - was no more
> > likely in volunteers in simulated airplane cabins where
> > the pressure was equivalent to 8,000 feet above sea level
> > than it was when the pressure was closer to sea level.
>
> > But after three hours of exposure to cabin pressures
> > equivalent to 7,000 to 8,000 feet, the simulated fliers
> > were more likely than others to report backaches,
> > headaches, shortness of breath, light- headedness and
> > impaired coordination.
>
> > Women and younger people were the most likely to
> > experience symptoms. "On the basis of our findings, we
> > conclude that maintaining a cabin altitude of 6,000 feet
> > or lower (equivalent to a barometric pressure of 609 mm Hg
> > or higher) on long-duration commercial flights will reduce
> > the discomfort among passengers," wrote Michael Muhm and
> > colleagues.
>
> > -----------------------------------
>
> > Briefs: Flying may pose risk to sleep apnea sufferers By
> > Times Staff, Wires In print: Friday, May 23, 2008
>
> > Flying may pose risk to sleep apnea sufferers
>
> > People with severe obstructive sleep apnea (OSA) taking
> > airline flights may have a greater risk from cardiac
> > stress than healthy people, according to new research. The
> > scientists compared oxygen levels and breathing by
> > simulating flight conditions. "It is normal for the rate
> > of breathing to increase when air pressure falls,'' said
> > Leigh Seccombe, an Australian scientist. "We found that
> > (for those with OSA), their breathing intensity increases
> > at about the same rate as it does in healthy people." But
> > the physiological stress and demand for oxygen was
> > increased in people with OSA. "The work they do to run the
> > core range of body functions (heart, lungs, brain) is much
> > greater under cabin conditions.''
>
> > Who loves ya. Tom
>
> > Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> > Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> > =A0DEAD PEOPLE WALKING =A0http://tinyurl.com/zk9fk- Hide
> > quoted text -
>
> - Show quoted text -
Ironjustic
Wed, May-28-08, 17:16
On May 28, 8:14 am, ironjustice <teamtan...@hotmail.com>
wrote: thrombosis <<
"Symptoms usually begin 6-24 hours after arrival"
http://www.rnceus.com/altitude/sickness.html
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
> On May 26, 10:34 am, ironjustice <ironjust...@cashette.com>
> wrote: thrombosis <<
>
> People are still under the assumption it is the cramped
> seating conditions which causes thrombosis ..
>
> It's not ..
>
> Vol. 119, No. 3, 2008 --------------------------------------
> -------------------------------------=
-=AD-----
>
> Review
>
> Altitude and Coagulation Activation: Does Going High Provoke
> Thrombosis?
> J.J. van Veena, M. Makrisb
>
> aLeicester Haemophilia Comprehensive Care Centre and
> Haemostasis and Thrombosis Unit, Leicester , and bSheffield
> Haemophilia and Thrombosis Centre, Sheffield, UK
>
> Address of Corresponding Author
>
> Acta Haematol 2008;119:156-157 (DOI: 10.1159/000128045)
>
> Who loves ya. Tom
>
> Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
>
>
>
> > They've decided to NOT raise the cabin pressure .. Not
> > enough evidence .. They aren't counting the db's .. just
> > the cash ..
>
> > Reminds me of the water heaters which had the 'defect' ..
> > they decided it was "cheaper" to pay off the explosions
> > and screaming deaths than to recall.
>
> > "8000 ft has been accepted as the maximum operational
> > cabin pressure altitude in the airline industry."
>
> > "On the basis of our findings, we conclude that
> > maintaining a cabin altitude of 6,000 feet or lower
> > (equivalent to a barometric pressure of 609 mm Hg or
> > higher) on long-duration commercial flights will reduce
> > the discomfort among passengers,"
>
> > Cabin cruising altitudes for regular transport aircraft.
> > [Journal Article] Aviat Space Environ Med 2008 Apr;
> > 79(4):433-9.
>
> > The adverse physiological effects of flight, caused by
> > ascent to altitude and its associated reduction in
> > barometric pressure, have been known since the first
> > manned balloon flights in the 19th century. It soon
> > became apparent that the way to protect the occupant of
> > an aircraft from the effects of ascent to altitude was
> > to enclose either the individual, or the cabin, in a
> > sealed or pressurized environment. Of primary concern in
> > commercial airline transport operations is the selection
> > of a suitable cabin pressurization schedule that assures
> > adequate oxygen partial pressures for all intended
> > occupants. For the past several decades, 8000 ft has
> > been accepted as the maximum operational cabin pressure
> > altitude in the airline industry. More recent research
> > findings on the physiological and psycho- physiological
> > effects of mild hypoxia have provided cause for renewed
> > discussion of the "acceptability" of a maximum cabin
> > cruise altitude of 8000 ft; however, we did not find
> > sufficient scientific data to recommend a change in the
> > cabin altitude of transport category aircraft. The
> > Aerospace Medical Association (AsMA) should support
> > further research to evaluate the safety, performance and
> > comfort of occupants at altitudes between 5000 and
> > 10,000 ft.
>
> > Aviation, space, and environmental medicine [Aviat Space
> > Environ Med] ---------------------------------------------
> > ----------------------------=
---=AD=AD-----
>
> > Long flights cause altitude sickness 6 Jul 2007, 0002 hrs
> > IST,REUTERS
>
> > BOSTON: Feeling a little achy, light headed or short of
> > breath on a long plane flight? A new study suggests you
> > might be suffering from a mild form of altitude sickness.
>
> > Until now, such symptoms had been attributed to jet lag,
> > dehydration, air contamination or being stuck in a cramped
> > seat for hours.
>
> > Researchers report that true altitude sickness - with its
> > nausea, vomiting and sleep disturbances - was no more
> > likely in volunteers in simulated airplane cabins where
> > the pressure was equivalent to 8,000 feet above sea level
> > than it was when the pressure was closer to sea level.
>
> > But after three hours of exposure to cabin pressures
> > equivalent to 7,000 to 8,000 feet, the simulated fliers
> > were more likely than others to report backaches,
> > headaches, shortness of breath, light- headedness and
> > impaired coordination.
>
> > Women and younger people were the most likely to
> > experience symptoms. "On the basis of our findings, we
> > conclude that maintaining a cabin altitude of 6,000 feet
> > or lower (equivalent to a barometric pressure of 609 mm Hg
> > or higher) on long-duration commercial flights will reduce
> > the discomfort among passengers," wrote Michael Muhm and
> > colleagues.
>
> > -----------------------------------
>
> > Briefs: Flying may pose risk to sleep apnea sufferers By
> > Times Staff, Wires In print: Friday, May 23, 2008
>
> > Flying may pose risk to sleep apnea sufferers
>
> > People with severe obstructive sleep apnea (OSA) taking
> > airline flights may have a greater risk from cardiac
> > stress than healthy people, according to new research. The
> > scientists compared oxygen levels and breathing by
> > simulating flight conditions. "It is normal for the rate
> > of breathing to increase when air pressure falls,'' said
> > Leigh Seccombe, an Australian scientist. "We found that
> > (for those with OSA), their breathing intensity increases
> > at about the same rate as it does in healthy people." But
> > the physiological stress and demand for oxygen was
> > increased in people with OSA. "The work they do to run the
> > core range of body functions (heart, lungs, brain) is much
> > greater under cabin conditions.''
>
> > Who loves ya. Tom
>
> > Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> > Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> > DEAD PEOPLE WALKING http://tinyurl.com/zk9fk- Hide quoted
> > text -
>
> - Show quoted text -
Ironjustic
Wed, May-28-08, 17:16
On May 28, 8:55 am, ironjustice <teamtan...@hotmail.com>
wrote: "Symptoms usually begin 6-24 hours after arrival"
http://tinyurl.com/4u4mp3
"The coalition recommends these measures for all passengers on
flights of six or more hours: "
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
> On May 28, 8:14 am, ironjustice <teamtan...@hotmail.com>
> wrote: thrombosis <<
>
> "Symptoms usually begin 6-24 hours after arrival"
>
> http://www.rnceus.com/altitude/sickness.html
>
> Who loves ya. Tom
>
> Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
>
>
>
> > On May 26, 10:34 am, ironjustice
> > <ironjust...@cashette.com> wrote: thrombosis <<
>
> > People are still under the assumption it is the cramped
> > seating conditions which causes thrombosis ..
>
> > It's not ..
>
> > Vol. 119, No. 3, 2008 ------------------------------------
> > -------------------------------------=
---=AD=AD-----
>
> > Review
>
> > Altitude and Coagulation Activation: Does Going High
> > Provoke Thrombosis?
> > J.J. van Veena, M. Makrisb
>
> > aLeicester Haemophilia Comprehensive Care Centre and
> > Haemostasis and Thrombosis Unit, Leicester , and
> > bSheffield Haemophilia and Thrombosis Centre,
> > Sheffield, UK
>
> > Address of Corresponding Author
>
> > Acta Haematol 2008;119:156-157 (DOI: 10.1159/000128045)
>
> > Who loves ya. Tom
>
> > Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> > Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> > DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
>
> > > They've decided to NOT raise the cabin pressure .. Not
> > > enough evidence .. They aren't counting the db's .. just
> > > the cash ..
>
> > > Reminds me of the water heaters which had the 'defect'
> > > .. they decided=
> > > it was "cheaper" to pay off the explosions and screaming
> > > deaths than to recall.
>
> > > "8000 ft has been accepted as the maximum operational
> > > cabin pressure altitude in the airline industry."
>
> > > "On the basis of our findings, we conclude that
> > > maintaining a cabin altitude of 6,000 feet or lower
> > > (equivalent to a barometric pressure of 609 mm Hg or
> > > higher) on long-duration commercial flights will reduce
> > > the discomfort among passengers,"
>
> > > Cabin cruising altitudes for regular transport aircraft.
> > > [Journal Article] Aviat Space Environ Med 2008 Apr;
> > > 79(4):433-9.
>
> > > The adverse physiological effects of flight, caused by
> > > ascent to altitude and its associated reduction in
> > > barometric pressure, have been known since the first
> > > manned balloon flights in the 19th century. It soon
> > > became apparent that the way to protect the occupant of
> > > an aircraft from the effects of ascent to altitude was
> > > to enclose either the individual, or the cabin, in a
> > > sealed or pressurized environment. Of primary concern in
> > > commercial airline transport operations is the selection
> > > of a suitable cabin pressurization schedule that assures
> > > adequate oxygen partial pressures for all intended
> > > occupants. For the past several decades, 8000 ft has
> > > been accepted as the maximum=
> > > operational cabin pressure altitude in the airline
> > > industry. More recent research findings on the
> > > physiological and psycho- physiological effects of mild
> > > hypoxia have provided cause for renewed discussion of
> > > the "acceptability" of a maximum cabin cruise altitude
> > > of 8000 ft; however, we did not find sufficient
> > > scientific data to recommend a change in the cabin
> > > altitude of transport category aircraft. The Aerospace
> > > Medical Association (AsMA) should support further
> > > research to evaluate the safety, performance and comfort
> > > of occupants at altitudes between 5000 and 10,000 ft.
>
> > > Aviation, space, and environmental medicine [Aviat Space
> > > Environ Med] -------------------------------------------
> > > ----------------------------=
-----=AD=AD=AD-----
>
> > > Long flights cause altitude sickness 6 Jul 2007, 0002
> > > hrs IST,REUTERS
>
> > > BOSTON: Feeling a little achy, light headed or short of
> > > breath on a long plane flight? A new study suggests you
> > > might be suffering from a mild form of altitude
> > > sickness.
>
> > > Until now, such symptoms had been attributed to jet lag,
> > > dehydration, air contamination or being stuck in a
> > > cramped seat for hours.
>
> > > Researchers report that true altitude sickness - with
> > > its nausea, vomiting and sleep disturbances - was no
> > > more likely in volunteers in simulated airplane cabins
> > > where the pressure was equivalent to 8,000 feet above
> > > sea level than it was when the pressure was closer to
> > > sea level.
>
> > > But after three hours of exposure to cabin pressures
> > > equivalent to 7,000 to 8,000 feet, the simulated fliers
> > > were more likely than others to report backaches,
> > > headaches, shortness of breath, light- headedness and
> > > impaired coordination.
>
> > > Women and younger people were the most likely to
> > > experience symptoms. "On the basis of our findings, we
> > > conclude that maintaining a cabin altitude of 6,000 feet
> > > or lower (equivalent to a barometric pressure of 609 mm
> > > Hg or higher) on long-duration commercial flights will
> > > reduce the discomfort among passengers," wrote Michael
> > > Muhm and colleagues.
>
> > > -----------------------------------
>
> > > Briefs: Flying may pose risk to sleep apnea sufferers By
> > > Times Staff, Wires In print: Friday, May 23, 2008
>
> > > Flying may pose risk to sleep apnea sufferers
>
> > > People with severe obstructive sleep apnea (OSA) taking
> > > airline flights may have a greater risk from cardiac
> > > stress than healthy people, according to new research.
> > > The scientists compared oxygen levels and breathing by
> > > simulating flight conditions. "It is normal for the rate
> > > of breathing to increase when air pressure falls,'' said
> > > Leigh Seccombe, an Australian scientist. "We found that
> > > (for those with OSA), their breathing intensity
> > > increases at about the same rate as it does in healthy
> > > people." But the physiological stress and demand for
> > > oxygen was increased in people=
> > > with OSA. "The work they do to run the core range of
> > > body functions (heart, lungs, brain) is much greater
> > > under cabin conditions.''
>
> > > Who loves ya. Tom
>
> > > Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> > > Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> > > DEAD PEOPLE WALKING http://tinyurl.com/zk9fk-Hide
> > > quoted text -
>
> > - Show quoted text -- Hide quoted text -
>
> - Show quoted text -
Ironjustic
Thu, May-29-08, 06:16
On May 28, 9:03=A0am, ironjustice <teamtan...@hotmail.com>
wrote: erythrocytosis <<
Sleep apnea and erythrocytosis coexist and erythrocytosis /
sleep apnea is a sign of "don't fly if you have sleep apnea"
because of thrombosis.
http://tinyurl.com/yclscm
Thrombosis is very common in lupus . Erythrocytosis /
polycythemia causes thrombosis. Erythrocytosis "doesn't exist
in lupus" even though all the drugs 'they' sell you and all
the signs and symptoms say it DOES .. .
They say they have no idea what causes the thrombosis problems
in lupus BUT you know they sell you drugs which are KNOWN to
control **erythrocytosis** .and you KNOW erythrocytosis causes
thrombosis . You KNOW treatments which treat erythrocytosis
lead to CURE in disease which closely resembles lupus. IE:
thalassemia and sickle / aplastic anemia.
You know lupus manifests at altitude and altitude causes
erythrocytosis.
But .. erythrocytosis .. isn't .. involved IN .. lupus .. ?
Need a bridge .. ?
Another sign of .. erythrocytosis .. is .. increased blood
viscosity .. since increased red blood cell production /
erythrocytosis leads to increased blood viscosity .. thicker
more 'syrup' like blood.
Sooo .. does increased viscosity APPEAR .. in .. lupus .. ?
Yep ..
http://serials.cib.unibo.it/cgi-ser/start/it/spogli/df-s.tcl?-
prog_art=3D3D429=3D
3343&language=3D3DITALIANO&view=3D3Darticoli
Catalogo Articoli (Spogli Riviste) OPAC HELP
Titolo: Elevated blood viscosity in systemic lupus
erythematosus
Autore: Rosenson, RS; Shott, S; Katz, R; Indirizzi:
Northwestern Univ, Sch Med, Prevent Cardiol Ctr, Chicago, IL
60611 USA Northwestern Univ Chicago IL USA 60611 Cardiol Ctr,
Chicago, IL 60611 USA Rush Presbyterian St Lukes Med Ctr,
Biostat Unit, Dept Neurosurg, Chicago,IL 60612 USA Rush
Presbyterian St Lukes Med Ctr Chicago IL USA 60612 cago,IL
60612 USA Rush Presbyterian St Lukes Med Ctr, Dept Med,
Rheumatol Sect, Chicago, IL 60612 USA Rush Presbyterian St
Lukes Med Ctr Chicago IL USA 60612 ago, IL 60612 USA
Titolo Testata: SEMINARS IN ARTHRITIS AND RHEUMATISM
fascicolo: 1, volume: 31, anno: 2001, pagine: 52 - 57 SICI:
0049-0172(200108)31:1<52:EBVISL>2.0.ZU;2-L Fonte: ISI Lingua:
ENG Soggetto: EMISSION COMPUTED-TOMOGRAPHY; DISEASE
RISK-FACTORS; CARDIOVASCULAR MANIFESTATIONS; ARTERY;
LIPOPROTEIN; ANTIBODIES; COHORT; INDEX; MEN; Keywords:
systemic lupus erythematosus; blood viscosity; rheology;
cardiovascular risk; Tipo documento: Review Natura: Periodico
Settore Disciplinare: Clinical Medicine Citazioni: 34
Recensione: Indirizzi per estratti: Indirizzo: Rosenson, RS
Northwestern Univ, Sch Med, Prevent Cardiol Ctr, 250 E Super
St,Wesley 728, Chicago, IL 60611 USA Northwestern Univ 250 E
Super St,Wesley 728 Chicago IL USA 60611
--------------------------------------------------------------
--------------=3D
-----
Abstract Objectives: It has been proposed that elevated blood
viscosity contributes to atherothrombotic and thromboembolic
processes. We evaluated whether there is increased blood
viscosity in systemic lupus erythematosus (SLE) that might
contribute to cardiovascular complications and reduced tissue
perfusion. Methods: Blood viscosity profiles were evaluated
inSLE patients to determine whether rheologic
disturbancescontribute to the cardiovascular risk profile.
Blood viscosity profiles were evaluated in 27 patients with
SLE and 46 age- and gender-matched controls. Blood viscosity
was measured at 37 degrees C and shear rates of 1 s(-1) and
100 s(-1), then corrected to the average hematocrit of the SLE
patients. Results. Corrected blood viscosity values were
higher in SLE patients than in controls at 100 s(-1) (P =3D3D
.002). Positive correlations were found between the Systemic
Lupus Damage Index for SLE, which quantifies damage to12 organ
systems and fibrinogen (rho =3D3D .39; P =3D3D .042) and
plasma viscosity (rho=3D3D .38, P =3D3D .049). Conclusions:
Our data indicate that =3D blood viscosityvalues at a standard
hematocrit are elevated in SLE patients. Further
investigations are needed to evaluate whether the increased
blood viscosity values in SLE patients contribute to
cardiovascular complications and tissue ischemia. Clinical
Relevance: Because blood viscosity values correlate with the
clinical severity of SLE, blood viscosity may contribute to
the cardiovascular complications and reduced tissue perfusion
in SLE patients. Copyright (C) 2001 by W.B. Saunders Company.
-----------------------------
CIB Centro Inter-Bibliotecario, Universit=3DE0 di Bologna,
Catalogo delle riviste ed altri periodici Documento generato
il 26/03/07 alle ore 15:23:15 International Collaborating
Clinics/American College of Rheumatology
---------------------------------
This is mere .. coincidence of course .. phlebotomy /
venesection / bloodletting .. leads to **resolution** of ..
erythematous lesions on the center of the face.
Phlebotomy / venesection / bloodletting .. is the PREFERRED ..
first treatment .. OF .. erythrocytosis ..
Coincidence .. of .. course ..
Rosacea associated with polycythemia vera: Skin lesions
improved with phlebotomy ADSuhr,Ki-Beom; Yoon, Ji-Seong;
Lee, Jeung-Hoon; Park, Jang-Kyu 1994 Annals of Dermatology
6(1): 98-101
We report a case of rosacea in a 65 year old female with a 14
year history of polycythemia vera. The patient suffered
fromseveral constitutional symptoms and signs suggestive
ofpolycythemia vera. Six years prior to our initial
examination,erythematous lesions were first noted on the
center of the face. These lesions exhibited periodic
improvement and exacerbation without specific treatment.
Histopathologicexamination of the facial lesions showed
nodular infiltrationof lymphocytes and histiocytes and
dilation of blood vessels. On the basis of laboratory
examination, the patient was diagnosed as polycythemia vera.
The patient has receivedmetronidazole, tetracycline, and
topical steroids to controlrosacea- like facial lesions. The
treatment results were notsignificant. However, phlebotomy
markedly improved the skin lesion. To our knowledge, there are
no reports describing the clinical course of rosacea lesions
following the treatment with phlebotomy.
--------------------
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
Taka
Thu, May-29-08, 06:16
So should we be practicing bloodletting before long haul
flights? The physicians are recommending taking aspirin
before. You may say aspirin binds iron but its more
important function is COX inhibition. It's all about
arachidonic acid overload.
Taka
Ironjustic
Thu, May-29-08, 17:15
On May 28, 5:56=A0pm, Taka <taka0...@gmail.com> wrote:It's all
about arachidonic acid overload <<
Sooo .. as opposed to the information I've provided as to the
**proximate** cause OF the thrombosis .. you .. 'say' .. it's
all about arachidonic acid .. ?
Need a cite or two for that I think.
Arachidonic acid causes hyperviscosity .. ??
Show JUST that one .. just one cite which shows arachidonic
acid causes .. hyperviscosity ..
Warfarin against .. arachidonic acid / hyperviscosity ..
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
> So should we be practicing bloodletting before long haul
> flights? =A0The physicians are recommending taking aspirin
> before. =A0You may say aspirin binds iron but its more
> important function is COX inhibition. It's all about
> arachidonic acid overload.
>
> Taka
Ironjustic
Thu, May-29-08, 17:15
On May 29, 10:08=A0am, "Manky Badger"
<you.m...@be.joking> wrote: the anti-gravity effects of
iron reduction on red cells. <<
You are on this thread for a reason .. ?
You are AGAIN .. doctoring .. information ..
Eh ..
Is that the extent of your .. abilities .. ?
Doctoring medical studies .. doctoring posts .. and ..
attempting to belittle .. ?
Is it .. "I am a scientist with credentials" ..
Ehhh ..
Dweeb ..
Always will be a dweeb ..
Now unless you have something to say about .. aplastic anemia
and the risk of dying while flying .. maybe you should crawl
back under whatever shtpiles guys like you crawl out .. from
.. under ..
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
> "ironjustice" <teamtan...@hotmail.com> wrote in message
>
> news:94c42fb6-dbe2-4425-b1c3-ca441305f0fe@k37g2000hsf.googl-
> egroups.com... On May 28, 5:56 pm, Taka <taka0...@gmail.com>
> wrote:It's all aboutarachido=
nicacid overload <<
>
> Sooo .. as opposed to the information I've provided as to
> the **proximate** cause OF the thrombosis .. you .. 'say' ..
> it's all aboutarachidonicacid .. ?
>
> Need a cite or two for that I think.
>
> Arachidonicacid causes hyperviscosity .. ??
>
> Show JUST that one .. just one cite which
> showsarachidonicacid causes .. hyperviscosity ..
>
> Warfarin against ..arachidonicacid / hyperviscosity .. -----
> ------------------------------------------------------------
> -----------=
-=AD-----------------------------
>
> (Sorry, I *know* I shouldn't feed the troll)
>
> Tommy - you demonstrate your ignorance yet again. I shall
> addarachidonicacid to the list which includes (among
> other gems):
>
> "disease which closely resembles lupus. IE: thalassemia and
> sickle / aplastic anemia" sequestration of minerals the
> anti-gravity effects ofironreduction on red cells.
>
> Why on earth do you post this stuff? Again your theories
> seem perfectly plausible to anyone who knows absolutel=
y
> nothing about the subject. (This is your cue to swear
> without the vowels and call me childish names)
Manky Badg
Thu, May-29-08, 17:15
"ironjustice" <teamtanner@hotmail.com> wrote in message news:-
94c42fb6-dbe2-4425-b1c3-ca441305f0fe@k37g2000hsf.googlegroups-
.com... On May 28, 5:56 pm, Taka <taka0...@gmail.com>
wrote:It's all about arachidonic acid overload <<
Sooo .. as opposed to the information I've provided as to the
**proximate** cause OF the thrombosis .. you .. 'say' .. it's
all about arachidonic acid .. ?
Need a cite or two for that I think.
Arachidonic acid causes hyperviscosity .. ??
Show JUST that one .. just one cite which shows arachidonic
acid causes .. hyperviscosity ..
Warfarin against .. arachidonic acid / hyperviscosity ..
--------------------------------------------------------------
-------------------------------------------
(Sorry, I *know* I shouldn't feed the troll)
Tommy - you demonstrate your ignorance yet again. I shall
add arachidonic acid to the list which includes (among
other gems):
"disease which closely resembles lupus. IE: thalassemia and
sickle / aplastic anemia" sequestration of minerals the
anti-gravity effects of iron reduction on red cells.
Why on earth do you post this stuff? Again your theories seem
perfectly plausible to anyone who knows absolutely nothing
about the subject. (This is your cue to swear without the
vowels and call me childish names)
Manky Badg
Thu, May-29-08, 17:15
"ironjustice" <teamtanner@hotmail.com> wrote in message news:-
3f706274-d2b6-498c-ac3b-0abfbb1c8698@25g2000hsx.googlegroups.-
com... On May 29, 10:08 am, "Manky Badger"
<you.m...@be.joking> wrote: the anti-gravity effects of iron
reduction on red cells. <<
You are on this thread for a reason .. ?
You are AGAIN .. doctoring .. information ..
_______________________________________________
When have I *ever* doctored information?
(Double dweeb with knobs on - no returns!!!)
paris
Thu, May-29-08, 17:15
"Is it .. "I am a scientist with credentials" .."
Interesting, we did not know that came with a hack license
in canada.
Manky Badg
Thu, May-29-08, 17:15
<paris@ferrous.com> wrote in message
news:483efb03$0$907$1c4686b2@news.club.cc.cmu.edu...
> "Is it .. "I am a scientist with credentials" .."
>
> Interesting, we did not know that came with a hack license
> in canada.
He's great isn't he. You have to laugh.
Ironjustic
Fri, May-30-08, 06:16
On May 29, 11:50=A0am, pa...@ferrous.com wrote: "Is it .. "I
am a scientist with credentials" .." <<
What .. came with a hack license in canada .. ?
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
>
> Interesting, we did not know that came with a hack license
> in canada.
Ironjustic
Fri, May-30-08, 06:16
On May 29, 7:56=A0am, ironjustice <teamtan...@hotmail.com>
wrote: hyperviscosity <<
My free bisphosphonate works well the iron chelator I
wonder why.
http://www.vrp.com/articles.aspx?ProdID=3Dart1170&zTYPE=3D2
"An overlooked anti-coagulant is Inositol Hexaphosphate (IP6).
In one study, IP6 inhibited platelet aggregation by 45 percent
in an in vivo animal model. In an in vitro study by the same
researchers, stickiness was induced in human whole blood taken
from healthy volunteers. IP6 reduced clotting by 50 percent,
or eliminated it altogether."
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
> On May 28, 5:56=A0pm, Taka <taka0...@gmail.com> wrote:It's
> all about arachidonic acid overload <<
>
> Sooo .. as opposed to the information I've provided as to
> the **proximate** cause OF the thrombosis .. you .. 'say' ..
> it's all about arachidonic acid .. ?
>
> Need a cite or two for that I think.
>
> Arachidonic acid causes hyperviscosity .. ??
>
> Show JUST that one .. just one cite which shows arachidonic
> acid causes .. hyperviscosity ..
>
> Warfarin against .. arachidonic acid / hyperviscosity ..
>
> Who loves ya. Tom
>
> Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> =A0DEAD PEOPLE WALKING =A0http://tinyurl.com/zk9fk
>
>
>
> > So should we be practicing bloodletting before long haul
> > flights? =A0The=
> > physicians are recommending taking aspirin before. =A0You
> > may say aspirin binds iron but its more important function
> > is COX inhibition. It's all about arachidonic acid
> > overload.
>
> > Taka- Hide quoted text -
>
> - Show quoted text -
Taka
Fri, May-30-08, 06:16
On May 29, 11:56 pm, ironjustice
<teamtan...@hotmail.com> wrote:
> On May 28, 5:56 pm, Taka <taka0...@gmail.com> wrote:It's all
> about arachidonic acid overload <<
>
> Sooo .. as opposed to the information I've provided as to
> the **proximate** cause OF the thrombosis .. you .. 'say' ..
> it's all about arachidonic acid .. ?
>
> Need a cite or two for that I think.
http://www.prostaglandinresearch.com/showcitationlist.php?mth-
=Thromboembolism
> Arachidonic acid causes hyperviscosity .. ??
>
> Show JUST that one .. just one cite which shows arachidonic
> acid causes .. hyperviscosity ..
>
> Warfarin against .. arachidonic acid / hyperviscosity ..
>
> Who loves ya. Tom
>
> Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
>
> > So should we be practicing bloodletting before long haul
> > flights? The physicians are recommending taking aspirin
> > before. You may say aspirin binds iron but its more
> > important function is COX inhibition. It's all about
> > arachidonic acid overload.
>
> > Taka
Ironjustic
Fri, May-30-08, 17:16
On May 29, 7:33=A0pm, Taka <taka0...@gmail.com> wrote:it's all
about arachidonic acid <<
Ok .. I gave a pretty good rendition of WHY a person with
lupus .. seems .. to be erythrocytotic .. AND .. when they FLY
.. they ..
die ..
Now .. when one flys .. erythrocytosis KILLS you /
thrombosis ..
NOW .. explain in a few words how YOU .. think .. lupus /
arachidonic acid .. makes one APPEAR to be erythrocytotic ..
too many red blood cells AND gives them the propensity to die
WHEN they fly.
We were given three different symptoms which might make one
die in flight .. and all of them seem to be lupus .. related.
You are saying .. it is NOT erythrocytosis which kills these
thick blooded people .. it is the .. arachidonic acid ..
Now why would arachidonic acid .. and flying .. kill people
with lupus .. ?
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
> On May 29, 11:56 pm, ironjustice
> <teamtan...@hotmail.com> wrote:
>
> > On May 28, 5:56 pm, Taka <taka0...@gmail.com> wrote:It's
> > all about arachidonic acid overload <<
>
> > Sooo .. as opposed to the information I've provided as to
> > the **proximate** cause OF the thrombosis .. you .. 'say'
> > .. it's all about arachidonic acid .. ?
>
> > Need a cite or two for that I think.
>
> http://www.prostaglandinresearch.com/showcitationlist.php?m-
> th=3DThrombo...=
>
>
>
> > Arachidonic acid causes hyperviscosity .. ??
>
> > Show JUST that one .. just one cite which shows
> > arachidonic acid causes .. hyperviscosity ..
>
> > Warfarin against .. arachidonic acid / hyperviscosity ..
>
> > Who loves ya. Tom
>
> > Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> > Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> > =A0DEAD PEOPLE WALKING =A0http://tinyurl.com/zk9fk
>
> > > So should we be practicing bloodletting before long haul
> > > flights? =A0T=
he
> > > physicians are recommending taking aspirin before.
> > > =A0You may say aspirin binds iron but its more important
> > > function is COX inhibition. It's all about arachidonic
> > > acid overload.
>
> > > Taka- Hide quoted text -
>
> - Show quoted text -
Ironjustic
Fri, May-30-08, 17:16
On May 30, 5:47=A0am, ironjustice <teamtan...@hotmail.com>
wrote:Arachidonic Acid <<
Arachidonic acid is part and parcel of our immune system. Much
like iron it has its .. place. Moderation .. But .. when there
is TOO much .. **iron** ..
"Increased Release of Arachidonic Acid"
ANY abnormal increase of arachidonic acid can be explained
with the iron overload / aplastic anemia / erythrocytosis / ..
hypothesis.
(Circulation. 2001;103:2395.) =A9 2001 American Heart
Association, Inc.
--------------------------------------------------------------
---------------=
----
Basic Science Reports
Increased Release of Arachidonic Acid and Eicosanoids in Iron-
Overloaded Cardiomyocytes Rafael Mattera, PhD; Gregory P.
Stone, BA; Nael Bahhur, BA; Yuri A. Kuryshev, PhD
=46rom Rammelkamp Center for Education and Research,
=MetroHealth Medical
Center (R.M., G.P.S., N.B., Y.A.K.) and Department of Medicine
(R.M.), Case Western Reserve University School of Medicine,
Cleveland, Ohio.
Correspondence to Rafael Mattera, PhD, Cell Biology and
Metabolism Branch, NICHD, Building 18T, Room 101, Bethesda, MD
20892. E-mail matterar@helix.nih.gov
Background=97Patients with transfusional iron overload may
develop a life-limiting cardiomyopathy. The sensitivity of
lipid-metabolizing enzymes to peroxidative injury, as well as
the reported effects of arachidonic acid (AA) and metabolites
on cardiac rhythm, led us to hypothesize that iron-overloaded
cardiomyocytes display alterations in the release of AA and
prostaglandins.
Methods and Results=97Neonatal rat ventricular myocytes
(NRVMs) cultured for 72 hours in the presence of 80 =B5g/mL
ferric ammonium citrate displayed an increased rate of AA
release, both under resting conditions and after stimulation
with agonists such as [Sar1]Ang II. Although iron treatment
did not affect overall incorporation of [3H]AA into NRVM
phospholipids, it caused a 2-fold increase in the distribution
of precursor in phosphatidylcholine species, with a
proportional decrease in phosphatidylinositol,
phosphatidylserine, and phosphatidylethanolamine. Increased
release of AA in iron-overloaded NRVMs was reduced by the
diacylglycerol lipase inhibitor RHC80267 but was largely
insensitive to inhibitors of phospholipases A2 and C. Iron-
overloaded cardiomyocytes also displayed increased production
of eicosanoids and induction of cyclooxygenase-2 after
stimulation with interleukin-1.
Conclusions=97Iron overload enhances AA release and
incorporation of AA into phosphatidylcholine, as well as
cyclooxygenase-2 induction and eicosanoid production, in
NRVMs. The effects of AA and metabolites on cardiomyocyte
rhythmicity suggest a causal connection between these signals
and electromechanical alterations in iron-overload=96induced
cardiomyopathy.
Key Words: cardiomyopathy =95 prostaglandins =95 signal
transduction =95 myocytes =95 iron
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
> On May 29, 7:33=A0pm, Taka <taka0...@gmail.com> wrote:it's
> all =A0about arachidonic acid <<
>
> Ok .. I gave a pretty good rendition of WHY a person with
> lupus .. seems .. to be erythrocytotic .. AND .. when they
> FLY .. they ..
> die ..
>
> Now .. when one flys .. erythrocytosis KILLS you /
> thrombosis ..
>
> NOW .. explain in a few words how YOU .. think .. lupus /
> arachidonic acid .. makes one APPEAR to be erythrocytotic ..
> too many red blood cells AND gives them the propensity to
> die WHEN they fly.
>
> We were given three different symptoms which might make one
> die in flight .. and all of them seem to be lupus ..
> related.
>
> You are saying .. it is NOT erythrocytosis which kills these
> thick blooded people .. it is the .. arachidonic acid ..
>
> Now why would arachidonic acid .. and flying .. kill people
> with lupus .. ?
>
> Who loves ya. Tom
>
> Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> =A0DEAD PEOPLE WALKING =A0http://tinyurl.com/zk9fk
>
>
>
> > On May 29, 11:56 pm, ironjustice <teamtan...@hotmail.com>
> > wrote:
>
> > > On May 28, 5:56 pm, Taka <taka0...@gmail.com> wrote:It's
> > > all about arachidonic acid overload <<
>
> > > Sooo .. as opposed to the information I've provided as
> > > to the **proximate** cause OF the thrombosis .. you ..
> > > 'say' .. it's all about arachidonic acid .. ?
>
> > > Need a cite or two for that I think.
>
> >http://www.prostaglandinresearch.com/showcitationlist.php?-
> >mth=3DThrombo..=
.
>
> > > Arachidonic acid causes hyperviscosity .. ??
>
> > > Show JUST that one .. just one cite which shows
> > > arachidonic acid causes .. hyperviscosity ..
>
> > > Warfarin against .. arachidonic acid / hyperviscosity ..
>
> > > Who loves ya. Tom
>
> > > Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> > > Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> > > =A0DEAD PEOPLE WALKING =A0http://tinyurl.com/zk9fk
>
> > > > So should we be practicing bloodletting before long
> > > > haul flights? =
=A0The
> > > > physicians are recommending taking aspirin before.
> > > > =A0You may say aspirin binds iron but its more
> > > > important function is COX inhibition=
.
> > > > It's all about arachidonic acid overload.
>
> > > > Taka- Hide quoted text -
>
> > - Show quoted text -- Hide quoted text -
>
> - Show quoted text -
Taka
Fri, May-30-08, 17:16
On May 30, 11:22 pm, ironjustice
<teamtan...@hotmail.com> wrote:
> On May 30, 5:47 am, ironjustice <teamtan...@hotmail.com>
> wrote:Arachidonic Acid <<
>
> Arachidonic acid is part and parcel of our immune system.
> Much like iron it has its .. place. Moderation .. But ..
> when there is TOO much .. **iron** ..
or TOO much **arachidonic acid** ... (has the iron intake
changed as much as the consumption of the linoleic acid rich
vegetable oils has since the beginning of last century? and is
there a system which blocks the linoleic acid absorption in
the human gut when there is enough of it inside the body? - as
you may know linoleic acid is converted into the arachidonic
acid by liver and any cell type generally)
> "Increased Release of Arachidonic Acid"
Do you know Tom, there are people who don't have any
appreciable amounts of arachidonic acid to speak of in their
bodies, like Ray Peat, Monty ...? What harm could possibly
iron do to them?
Taka
> ANY abnormal increase of arachidonic acid can be explained
> with the iron overload / aplastic anemia / erythrocytosis /
> .. hypothesis.
>
> (Circulation. 2001;103:2395.) =A9 2001 American Heart
> Association, Inc.
>
> ------------------------------------------------------------
> ---------------=
------
>
> Basic Science Reports
>
> Increased Release of Arachidonic Acid and Eicosanoids in
> Iron- Overloaded Cardiomyocytes Rafael Mattera, PhD; Gregory
> P. Stone, BA; Nael Bahhur, BA; Yuri A. Kuryshev, PhD From
> Rammelkamp Center for Education and Research, MetroHealth
> Medical Center (R.M., G.P.S., N.B., Y.A.K.) and Department
> of Medicine (R.M.), Case Western Reserve University School
> of Medicine, Cleveland, Ohio.
>
> Correspondence to Rafael Mattera, PhD, Cell Biology and
> Metabolism Branch, NICHD, Building 18T, Room 101, Bethesda,
> MD 20892. E-mail matte...@helix.nih.gov
>
> Background=97Patients with transfusional iron overload may
> develop a life-limiting cardiomyopathy. The sensitivity of
> lipid-metabolizing enzymes to peroxidative injury, as well
> as the reported effects of arachidonic acid (AA) and
> metabolites on cardiac rhythm, led us to hypothesize that
> iron-overloaded cardiomyocytes display alterations in the
> release of AA and prostaglandins.
>
> Methods and Results=97Neonatal rat ventricular myocytes
> (NRVMs) cultured for 72 hours in the presence of 80 =B5g/mL
> ferric ammonium citrate displayed an increased rate of AA
> release, both under resting conditions and after stimulation
> with agonists such as [Sar1]Ang II. Although iron treatment
> did not affect overall incorporation of [3H]AA into NRVM
> phospholipids, it caused a 2-fold increase in the
> distribution of precursor in phosphatidylcholine species,
> with a proportional decrease in phosphatidylinositol,
> phosphatidylserine, and phosphatidylethanolamine. Increased
> release of AA in iron-overloaded NRVMs was reduced by the
> diacylglycerol lipase inhibitor RHC80267 but was largely
> insensitive to inhibitors of phospholipases A2 and C. Iron-
> overloaded cardiomyocytes also displayed increased
> production of eicosanoids and induction of cyclooxygenase-2
> after stimulation with interleukin-1.
>
> Conclusions=97Iron overload enhances AA release and
> incorporation of AA into phosphatidylcholine, as well as
> cyclooxygenase-2 induction and eicosanoid production, in
> NRVMs. The effects of AA and metabolites on cardiomyocyte
> rhythmicity suggest a causal connection between these
> signals and electromechanical alterations in
> iron-overload=96induced cardiomyopathy.
>
> Key Words: cardiomyopathy =95 prostaglandins =95 signal
> transduction =95 myocytes =95 iron
>
> Who loves ya. Tom
>
> Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
>
> > On May 29, 7:33 pm, Taka <taka0...@gmail.com> wrote:it's
> > all about arachidonic acid <<
>
> > Ok .. I gave a pretty good rendition of WHY a person with
> > lupus .. seems .. to be erythrocytotic .. AND .. when they
> > FLY .. they ..
> > die ..
>
> > Now .. when one flys .. erythrocytosis KILLS you /
> > thrombosis ..
>
> > NOW .. explain in a few words how YOU .. think .. lupus /
> > arachidonic acid .. makes one APPEAR to be erythrocytotic
> > .. too many red blood cells AND gives them the propensity
> > to die WHEN they fly.
>
> > We were given three different symptoms which might make
> > one die in flight .. and all of them seem to be lupus ..
> > related.
>
> > You are saying .. it is NOT erythrocytosis which kills
> > these thick blooded people .. it is the .. arachidonic
> > acid ..
>
> > Now why would arachidonic acid .. and flying .. kill
> > people with lupus .. ?
>
> > Who loves ya. Tom
>
> > Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> > Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> > DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
>
> > > On May 29, 11:56 pm, ironjustice
> > > <teamtan...@hotmail.com> wrote:
>
> > > > On May 28, 5:56 pm, Taka <taka0...@gmail.com>
> > > > wrote:It's all about arachidonic acid overload <<
>
> > > > Sooo .. as opposed to the information I've provided as
> > > > to the **proximate** cause OF the thrombosis .. you ..
> > > > 'say' .. it's all about arachidonic acid .. ?
>
> > > > Need a cite or two for that I think.
>
> > >http://www.prostaglandinresearch.com/showcitationlist.ph-
> > >p?mth=3DThrombo=
...
>
> > > > Arachidonic acid causes hyperviscosity .. ??
>
> > > > Show JUST that one .. just one cite which shows
> > > > arachidonic acid causes .. hyperviscosity ..
>
> > > > Warfarin against .. arachidonic acid / hyperviscosity
> > > > ..
>
> > > > Who loves ya. Tom
>
> > > > Jesus Was A
> > > > Vegetarian!http://jesuswasavegetarian.7h.com
>
> > > > Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> > > > DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
>
> > > > > So should we be practicing bloodletting before long
> > > > > haul flights? =
The
> > > > > physicians are recommending taking aspirin before.
> > > > > You may say aspirin binds iron but its more
> > > > > important function is COX inhibiti=
on.
> > > > > It's all about arachidonic acid overload.
>
> > > > > Taka- Hide quoted text -
>
> > > - Show quoted text -- Hide quoted text -
>
> > - Show quoted text -
Ironjustic
Fri, May-30-08, 17:16
On May 30, 8:03=A0am, Taka <taka0...@gmail.com> wrote: is
there a system which blocks the linoleic acid absorption in
the human gut when there is enough of it inside the body? <<
Using .. logic .. ?
Yes .. taka .. there is ..
It is found in plants when you eat them isn't it .. ?
If I eat lots of plants high in linoleic acid will I die .. ?
If I eat healthy plants .. lots of plants .. plants which are
generally KNOWN to be good for you but HIGH in linoleic acid
will I deteriorate .. ?
I would say .. no ..
On May 30, 8:03 am, Taka <taka0...@gmail.com> wrote: Do you
know Tom, there are people who don't have any appreciable
amounts of arachidonic acid to speak of in their bodies,<<
These would be the healthy people then .. ?
On May 30, 8:03 am, Taka <taka0...@gmail.com> wrote: What harm
could possibly iron do to them? <<
Sooo .. what you are saying is .. "iron causes an increase in
arachidonic acid and this increase is seen in every disease
state involving iron" .. ?
Iron simply out and out rusts in the body .. you open a person
up and their insides are literally the color of rust and deep
brownish ..
WHAT kind of .. damage .. do YOU 'figure' .. ?
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
> On May 30, 11:22 pm, ironjustice
> <teamtan...@hotmail.com> wrote:
>
> > On May 30, 5:47 am, ironjustice <teamtan...@hotmail.com>
> > wrote:Arachidonic Acid <<
>
> > Arachidonic acid is part and parcel of our immune system.
> > Much like iron it has its .. place. Moderation .. But ..
> > when there is TOO much .. **iron** ..
>
> or TOO much **arachidonic acid** ... (has the iron intake
> changed as much as the consumption of the linoleic acid rich
> vegetable oils has since the beginning of last century? and
> is there a system which blocks the linoleic acid absorption
> in the human gut when there is enough of it inside the body?
> - as you may know linoleic acid is converted into the
> arachidonic acid by liver and any cell type generally)
>
> > "Increased Release of Arachidonic Acid"
>
> Do you know Tom, there are people who don't have any
> appreciable amounts of arachidonic acid to speak of in their
> bodies, like Ray Peat, Monty ...? =A0What harm could
> possibly iron do to them?
>
> Taka
>
>
>
> > ANY abnormal increase of arachidonic acid can be explained
> > with the iron overload / aplastic anemia / erythrocytosis
> > / =A0.. hypothesis.
>
> > (Circulation. 2001;103:2395.) =A9 2001 American Heart
> > Association, Inc.
>
> > ----------------------------------------------------------
> > ---------------=
---=AD-----
>
> > Basic Science Reports
>
> > Increased Release of Arachidonic Acid and Eicosanoids in
> > Iron- Overloaded Cardiomyocytes Rafael Mattera, PhD;
> > Gregory P. Stone, BA; Nael Bahhur, BA; Yuri A. Kuryshev,
> > PhD From Rammelkamp Center for Education and Research,
> > MetroHealth Medical Center (R.M., G.P.S., N.B., Y.A.K.)
> > and Department of Medicine (R.M.), Case Western Reserve
> > University School of Medicine, Cleveland, Ohio.
>
> > Correspondence to Rafael Mattera, PhD, Cell Biology and
> > Metabolism Branch, NICHD, Building 18T, Room 101,
> > Bethesda, MD 20892. E-mail matte...@helix.nih.gov
>
> > Background=97Patients with transfusional iron overload may
> > develop a life-limiting cardiomyopathy. The sensitivity of
> > lipid-metabolizing enzymes to peroxidative injury, as well
> > as the reported effects of arachidonic acid (AA) and
> > metabolites on cardiac rhythm, led us to hypothesize that
> > iron-overloaded cardiomyocytes display alterations in the
> > release of AA and prostaglandins.
>
> > Methods and Results=97Neonatal rat ventricular myocytes
> > (NRVMs) cultured=
> > for 72 hours in the presence of 80 =B5g/mL ferric ammonium
> > citrate displayed an increased rate of AA release, both
> > under resting conditions and after stimulation with
> > agonists such as [Sar1]Ang II. Although iron treatment did
> > not affect overall incorporation of [3H]AA into NRVM
> > phospholipids, it caused a 2-fold increase in the
> > distribution of precursor in phosphatidylcholine species,
> > with a proportional decrease in phosphatidylinositol,
> > phosphatidylserine, and phosphatidylethanolamine.
> > Increased release of AA in iron-overloaded NRVMs was
> > reduced by the diacylglycerol lipase inhibitor RHC80267
> > but was largely insensitive to inhibitors of
> > phospholipases A2 and C. Iron- overloaded cardiomyocytes
> > also displayed increased production of eicosanoids and
> > induction of cyclooxygenase-2 after stimulation with
> > interleukin-1.
>
> > Conclusions=97Iron overload enhances AA release and
> > incorporation of AA into phosphatidylcholine, as well as
> > cyclooxygenase-2 induction and eicosanoid production, in
> > NRVMs. The effects of AA and metabolites on cardiomyocyte
> > rhythmicity suggest a causal connection between these
> > signals and electromechanical alterations in
> > iron-overload=96induced cardiomyopathy.
>
> > Key Words: cardiomyopathy =95 prostaglandins =95 signal
> > transduction =95=
> > myocytes =95 iron
>
> > Who loves ya. Tom
>
> > Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> > Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> > =A0DEAD PEOPLE WALKING =A0http://tinyurl.com/zk9fk
>
> > > On May 29, 7:33 pm, Taka <taka0...@gmail.com> wrote:it's
> > > all =A0about arachidonic acid <<
>
> > > Ok .. I gave a pretty good rendition of WHY a person
> > > with lupus .. seems .. to be erythrocytotic .. AND ..
> > > when they FLY .. they ..
> > > die ..
>
> > > Now .. when one flys .. erythrocytosis KILLS you /
> > > thrombosis ..
>
> > > NOW .. explain in a few words how YOU .. think .. lupus
> > > / arachidonic acid .. makes one APPEAR to be
> > > erythrocytotic .. too many red blood cells AND gives
> > > them the propensity to die WHEN they fly.
>
> > > We were given three different symptoms which might make
> > > one die in flight .. and all of them seem to be lupus ..
> > > related.
>
> > > You are saying .. it is NOT erythrocytosis which kills
> > > these thick blooded people .. it is the .. arachidonic
> > > acid ..
>
> > > Now why would arachidonic acid .. and flying .. kill
> > > people with lupus .. ?
>
> > > Who loves ya. Tom
>
> > > Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> > > Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> > > =A0DEAD PEOPLE WALKING =A0http://tinyurl.com/zk9fk
>
> > > > On May 29, 11:56 pm, ironjustice
> > > > <teamtan...@hotmail.com> wrote:
>
> > > > > On May 28, 5:56 pm, Taka <taka0...@gmail.com>
> > > > > wrote:It's all about=
> > > > > arachidonic acid overload <<
>
> > > > > Sooo .. as opposed to the information I've provided
> > > > > as to the **proximate** cause OF the thrombosis ..
> > > > > you .. 'say' .. it's all about arachidonic acid .. ?
>
> > > > > Need a cite or two for that I think.
>
> > > >http://www.prostaglandinresearch.com/showcitationlist.-
> > > >php?mth=3DThrom=
bo...
>
> > > > > Arachidonic acid causes hyperviscosity .. ??
>
> > > > > Show JUST that one .. just one cite which shows
> > > > > arachidonic acid causes .. hyperviscosity ..
>
> > > > > Warfarin against .. arachidonic acid /
> > > > > hyperviscosity ..
>
> > > > > Who loves ya. Tom
>
> > > > > Jesus Was A
> > > > > Vegetarian!http://jesuswasavegetarian.7h.com
>
> > > > > Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> > > > > =A0DEAD PEOPLE WALKING =A0http://tinyurl.com/zk9fk
>
> > > > > > So should we be practicing bloodletting before
> > > > > > long haul flights=
? =A0The
> > > > > > physicians are recommending taking aspirin before.
> > > > > > =A0You may sa=
y
> > > > > > aspirin binds iron but its more important function
> > > > > > is COX inhibi=
tion.
> > > > > > It's all about arachidonic acid overload.
>
> > > > > > Taka- Hide quoted text -
>
> > > > - Show quoted text -- Hide quoted text -
>
> > > - Show quoted text -- Hide quoted text -
>
> - Show quoted text -
Manky Badg
Fri, May-30-08, 17:16
<ironjustice@aol.com> wrote in message news:e21eee72-5a12-447-
d-a3ea-2ad340ab00f4@t54g2000hsg.googlegroups.com...
Iron simply out and out rusts in the body .. you open a person
up and their insides are literally the color of rust and deep
brownish ..
_________________________________________________________
So what colour are the insides of those people with lower
iron levels?
Taka
Sat, May-31-08, 06:15
On May 31, 1:54 am, "Manky Badger" <you.m...@be.joking> wrote:
> <ironjust...@aol.com> wrote in message
>
> news:e21eee72-5a12-447d-a3ea-2ad340ab00f4@t54g2000hsg.googl-
> egroups.com...
>
> Iron simply out and out rusts in the body .. you open a
> person up and their insides are literally the color of rust
> and deep brownish ..
Iron with the valency +2 is green - all plants are green
because chlorophyl contains Fe+2
Iron with the valency +3 is red/brownish/rust - all blood and
muscle are red because hemoglobin and myoglobin contain Fe+3
The iron is in them for a reason, dead and ill people turn
pale white not red rust ...
Linoleic and alpha-linolenic acids are MINOR components of
plants except for some nuts but these also contain ample
antioxidants to counteract their oxidation by iron. You cannot
normally eat enough nuts to match the linoleic acid intake
from the modern processed foods like the fried items. Think a
bit quantitatively Tom.
Iron doesn't produce arachidonic acid, it rather oxidizes it
what leads to dangerous signaling proinflammatory molecules
like leukotrienes.
Taka
Ironjustic
Sat, May-31-08, 06:15
On May 30, 5:09=A0pm, Taka <taka0...@gmail.com> wrote: Iron
simply out and out rusts in the body .. you open a person up
and their insides are literally the color of rust and deep
brownish .. Iron with the valency +2 is green - all plants
are green because chlorophyl contains Fe+2 Iron with the
valency +3 is red/brownish/ rust - all blood and muscle are
red because hemoglobin and myoglobin contain Fe+3 The iron is
in them for a reason, dead and ill people turn pale white not
red rust <<
It is a well known fact of iron overload ..
On May 30, 5:09 pm, Taka <taka0...@gmail.com> wrote: Iron
doesn't produce arachidonic acid, <<
"Iron overload enhances AA release"
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
> On May 31, 1:54 am, "Manky Badger"
> <you.m...@be.joking> wrote:
>
> > <ironjust...@aol.com> wrote in message
>
> >news:e21eee72-5a12-447d-a3ea-2ad340ab00f4@t54g2000hsg.goog-
> >legroups.com...=
>
> > Iron simply out and out rusts in the body .. you open a
> > person up and their insides are literally the color of
> > rust and deep brownish ..
>
> Iron with the valency +2 is green - all plants are green
> because chlorophyl contains Fe+2
>
> Iron with the valency +3 is red/brownish/rust - all blood
> and muscle are red because hemoglobin and myoglobin
> contain Fe+3
>
> The iron is in them for a reason, dead and ill people turn
> pale white not red rust ...
>
> Linoleic and alpha-linolenic acids are MINOR components of
> plants except for some nuts but these also contain ample
> antioxidants to counteract their oxidation by iron. =A0You
> cannot normally eat enough nuts to match the linoleic acid
> intake from the modern processed foods like the fried items.
> =A0Think a bit quantitatively Tom.
>
> Iron doesn't produce arachidonic acid, it rather oxidizes it
> what leads to dangerous signaling proinflammatory molecules
> like leukotrienes.
>
> Taka
ironjustice wrote:
> They've decided to NOT raise the cabin pressure .. Not
> enough evidence .. They aren't counting the db's .. just
> the cash ..
>
> Reminds me of the water heaters which had the 'defect' ..
> they decided it was "cheaper" to pay off the explosions and
> screaming deaths than to recall.
>
---- and the Ford Motor company when they discovered defects
in a car and they decided it would be cheaper to compensate
the victims than to recall the cars and fix the problem. What
a surprise they had :-) We need a lot more of those.
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