Low Globulin Level

[Jaydee]

Hi . I just got my blood test back and found that my globulin
is 2.0 (range 2.1-3.7, but I've read other places that claim
it should be
2.5-3.5). The Albumin/Globulin range was 2.5 (range 1.0-2.1).

The rest of my blood test was normal.

Any thoughts?

Thanks!

- JayDee

[Marshall P]

JayDee wrote:
> Hi . I just got my blood test back and found that my
> globulin is 2.0 (range 2.1-3.7, but I've read other places
> that claim it should be
> 2.5-3.5). The Albumin/Globulin range was 2.5 (range
> 1.0-2.1).
>
> The rest of my blood test was normal.
>
> Any thoughts?
>
> Thanks!
>
> - JayDee

It depends on the lab. Each lab publishes its own set of
normal ranges.
(I've got a couple booklets around somewhere, but not
close at hand.)

About five or ten years ago, there was a doctor on the public
TV stations during pledge-drive time who said that
gamma-globulin levels from initial blood tests taken at the
time of admission to hospitals were a good indicator of
mortality. The higher a patient's initial gamma-globulin
level, the greater the likelihood he'd live.

--
Marshall Price of Miami Known to Yahoo as d021317c

[Jaydee]

On Mar 23, 8:20 am, Marshall Price <d0213...@yahoo.com> wrote:
> JayDee wrote:
> > Hi . I just got my blood test back and found that my
> > globulin is 2.0 (range 2.1-3.7, but I've read other places
> > that claim it should be
> > 2.5-3.5). The Albumin/Globulin range was 2.5 (range
> > 1.0-2.1).
>
> > The rest of my blood test was normal.
>
> > Any thoughts?
>
> > Thanks!
>
> > - JayDee
>
> It depends on the lab. Each lab publishes its own set of
> normal ranges.
> (I've got a couple booklets around somewhere, but not close
> at hand.)
>
> About five or ten years ago, there was a doctor on the
> public TV stations during pledge-drive time who said that
> gamma-globulin levels from initial blood tests taken at the
> time of admission to hospitals were a good indicator of
> mortality. The higher a patient's initial gamma-globulin
> level, the greater the likelihood he'd live.
>
> --
> Marshall Price of Miami Known to Yahoo as d021317c

oh boy... that's not very encouraging.

So does anyone know what causes this and if there's anything
one can do to raise their globulin levels? The doc told me it
was nothing to worry about and sometimes these results aren't
the most accurate when done by the lab I went to (Quest
diagnostics), but if there's anything I can do to improve this
number, please let me know!

Thanks.

- JayDee

[Mr-Natural]

On Mar 12, 3:56 pm, JayDee <dopam...@mail.com> wrote:
> Hi . I just got my blood test back and found that my
> globulin is 2.0 (range 2.1-3.7, but I've read other places
> that claim it should be
> 2.5-3.5). The Albumin/Globulin range was 2.5 (range
> 1.0-2.1).
>
> The rest of my blood test was normal.
>
> Any thoughts?

You are posting in the wrong newsgroup.

Try news:sci.med.laboratory
http://groups.google.com/group/sci.med.laboratory/topics

[Marshall P]

JayDee wrote:
> On Mar 23, 8:20 am, Marshall Price
> <d0213...@yahoo.com> wrote:
>> JayDee wrote:
>>> Hi . I just got my blood test back and found that my
>>> globulin is 2.0 (range 2.1-3.7, but I've read other places
>>> that claim it should be
>>> 2.5-3.5). The Albumin/Globulin range was 2.5 (range
>>> 1.0-2.1). The rest of my blood test was normal. Any
>>> thoughts? Thanks!
>>> - JayDee
>> It depends on the lab. Each lab publishes its own set of
>> normal ranges.
>>(I've got a couple booklets around somewhere, but not close
>> at hand.)
>>
>> About five or ten years ago, there was a doctor on the
>> public TV stations during pledge-drive time who said that
>> gamma-globulin levels from initial blood tests taken at the
>> time of admission to hospitals were a good indicator of
>> mortality. The higher a patient's initial gamma-globulin
>> level, the greater the likelihood he'd live.
>>
>> --
>> Marshall Price of Miami Known to Yahoo as d021317c
>
> oh boy... that's not very encouraging.
>
> So does anyone know what causes this and if there's anything
> one can do to raise their globulin levels? The doc told me
> it was nothing to worry about and sometimes these results
> aren't the most accurate when done by the lab I went to
> (Quest diagnostics), but if there's anything I can do to
> improve this number, please let me know!
>
> Thanks.
>
> - JayDee

Sorry, I forget who the doctor was, and I'm not familiar with
the subject. For what it's worth, I'm pretty sure it wasn't
Covert Bailey, Andrew Weil, or Nicholas Perricone.

Incidentally, /The Merck Manual 16/ contains an extensive list
of laboratory normal ranges in its "Special Subjects" section.
They're the ones used at the Massachusetts General Hospital
and published in NEJM.

Here's an excerpt:

Determination Reference Range

Protein: Total 6.0-8.4 gm/dL Albumin 3.5-5.0 gm/dL Globulin
2.3-3.5 gm/dL
Note: Globulin equals total protein minus albumin.
Electrophoresis % of total protein
Note: Quantitation by densitometry Albumin 52-68
Globulin: alpha-1 4.2-7.2 alpha-2 6.8-12 beta
9.3-15 gamma 13-23

I wouldn't give it a second thought, frankly. Perhaps you
could find out how variable it usually is from hour to hour,
assuming it depends on meals, exercise, sleep, growth, etc.,
but why distrust your doctor?

To me, the surprising thing is that it's the only measurement
that was out of range. Of ten independent tests, assuming the
normal range is from the 5th to the 95th percentiles, you'd
expect one to be out of range anyway, if I understand the
math, and it was very close.

--
Marshall Price of Miami Known to Yahoo as d021317c