Lecithin and Body Fat

[Ironjustic]

"Reduction of local fat was obtained in 91.9%"

Could a person lather up and "watch" the fat fall .. off .. ?
Vegetable lecithin applied topically has been shown to lower
cholesterol .. so theoretically it / phosphatidylcholine /
lecithin WOULD lower fat when .. eaten .. or .. applied
topically .. ?

Salti G, Ghersetich I, Tantussi F, Bovani B, Lotti T
Phosphatidylcholine and Sodium Deoxycholate in the Treatment
of Localized Fat: A Double-Blind, Randomized Study. [JOURNAL
ARTICLE] Dermatol Surg 2007 Dec 5.

BACKGROUND Recent articles have introduced the novel concept
of chemical lipolysis through local injections.
Phosphatidylcholine is the active drug in the commercial
preparation used for this purpose, but some studies have
suggested that sodium deoxycholate, an excipient of the
preparation, could be the real active substance. AIM We
decided to investigate whether phosphatidylcholine and sodium
deoxycholate have any clinical efficacy in chemical lipolysis
and their respective roles. We also studied the safety and
side effects of the treatments. MATERIALS AND METHODS
Thirty-seven consecutive female patients were studied for the
treatment of localized fat in gynoid lipodystrophy. Each
patient received injections of a phosphatidylcholine/sodium
deoxycholate preparation on one side and sodium deoxycholate
on the contralateral side, each single patient being herself
the control. Four treatments were carried out every 8 weeks in
a double-blind, randomized fashion. Metric circumferential
evaluations and photographic and ultrasonographic measurements
throughout the study allowed for final judgment. A statistical
evaluation concluded our study. RESULTS An overall reduction
of local fat was obtained in 91.9% of the patients without
statistically significant differences between the treated
sides. Reduction values on the phosphatidylcholine/sodium
deoxycholate-treated sides are in the order of 6.46%
metrically and
36.87% ultrasonographically, whereas on the
deoxycholate-treated sides they are in the order of 6.77%
metrically and 36.06% ultrasonographically. Both
treatments, at the dose used in the study, proved safe in
the short term. The most common side effects were local and
few, but were more pronounced on the deoxycholate-treated
sides. No laboratory test was carried out. CONCLUSION Both
treatments have shown moderate and equivalent efficacy in
treating localized fat, with sodium deoxycholate having a
slower postoperative resolution, suggesting that sodium
deoxycholate could be sufficient by itself to determine fat
cell destruction and that phosphatidylcholine could be
useful for obtaining a later emulsification of the fat.

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Dermatol Surg

Who loves ya. Tom

Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com

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[Ironjustic]

On Dec 15, 6:42 am, ironjustice <teamtan...@hotmail.com>
wrote: vegetable lecithin lather? <<

"Alternatives to invasive surgical procedures"

Co AC, Abad-Casintahan MF, Espinoza-Thaebtharm A Submental fat
reduction by mesotherapy using phosphatidylcholine alone
vs. phosphatidylcholine and organic silicium: a pilot study.
[Journal Article] J Cosmet Dermatol 2007 Dec; 6(4):250-7.

Background Excess skin and fatty tissues beneath the jaw lead
to a double chin deformity. Localized fat deposits in this
area are a cause of discomfort and anguish, leading patients
to undergo surgical procedures such as liposuction and
dermolipectomy to improve the cosmetic effect. Both procedures
require anesthesia and an operating room setting and are quite
expensive. Fearful of extensive surgery and its complications,
patients and physicians seek less invasive methods.
Mesotherapy with phosphatidylcholine and other cocktails have
been used to treat localized fat deposits. However, there are
few published articles regarding its effectiveness and some
are even anecdotal. Objective This study aims to determine the
efficacy of phosphatidylcholine alone
vt. phosphatidylcholine and organic silicium in submental fat
reduction. Methods Twelve patients with submental fat
deposit with no coexisting morbidity and with informed
consent were included in the study. They were submitted to
one to five treatment sessions with an average interval of
2 weeks between each session. The medication administered
was injected, either pure phosphatidylcholine or a
combination of phosphatidylcholine and organic silicium.
Baseline measurements of submental fat using vernier
caliper and digital photographs of the patients were taken
during each treatment session. The occurrence of adverse
effects was likewise noted. Results Among the 12 patients,
11 completed the treatment course, and 1 was excluded from
the study because of failure to follow up. Both
phosphatidylcholine and a combination of
phosphatidylcholine and organic silicium were equally
effective in reducing submental fat deposits. There was no
significant difference as to the rate and degree of
reduction. Significant reduction in the thickness of
submental fat was achieved after three treatment sessions.
Adverse reactions in both groups were mild and transitory
ranging from heavy sensation, localized heat, nodulations,
and slight bruising that abated 3 to 5 days after
treatment. Limitations As of this writing, information on
the use of both phosphatidylcholine and organic silicium
for mesotherapy of localized fat such as the submental
area is scarce. The exact mechanisms of action of both
treatments are likewise unknown. Ultrasound and
histopathological changes were not documented. The study
did not involve a double-blind, placebo- controlled
design, and the sample size was small. Conclusion
Mesotherapy using phosphatidylcholine vs.
phosphatidylcholine plus organic silicium was similarly
effective in reducing submental fat. There was no
significant difference between them in terms of rate and
degree of reduction. Optimal reduction of submental fat
was achieved after three treatment sessions. Adverse
reactions were few, mild, and transitory. Therefore, both
regimens are safe, efficacious, cost- effective, and can
be used as alternatives to invasive surgical procedures.

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-------------------
More from this journal Journal of cosmetic dermatology [J
Cosmet Dermatol]

Who loves ya. Tom

Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com

Man Is A Herbivore! http://tinyurl.com/a3cc3

DEAD PEOPLE WALKING http://tinyurl.com/zk9fk

> "Reduction of local fat was obtained in 91.9%"
>
> Could a person lather up and "watch" the fat fall .. off ..
> ? Vegetable lecithin applied topically has been shown to
> lower cholesterol .. so theoretically it /
> phosphatidylcholine / lecithin WOULD lower fat when .. eaten
> .. or .. applied topically .. ?
>
> Salti G, Ghersetich I, Tantussi F, Bovani B, Lotti T
> Phosphatidylcholine and Sodium Deoxycholate in the Treatment
> of Localized Fat: A Double-Blind, Randomized Study. [JOURNAL
> ARTICLE] Dermatol Surg 2007 Dec 5.
>
> BACKGROUND Recent articles have introduced the novel concept
> of chemical lipolysis through local injections.
> Phosphatidylcholine is the active drug in the commercial
> preparation used for this purpose, but some studies have
> suggested that sodium deoxycholate, an excipient of the
> preparation, could be the real active substance. AIM We
> decided to investigate whether phosphatidylcholine and
> sodium deoxycholate have any clinical efficacy in chemical
> lipolysis and their respective roles. We also studied the
> safety and side effects of the treatments. MATERIALS AND
> METHODS Thirty-seven consecutive female patients were
> studied for the treatment of localized fat in gynoid
> lipodystrophy. Each patient received injections of a
> phosphatidylcholine/sodium deoxycholate preparation on one
> side and sodium deoxycholate on the contralateral side, each
> single patient being herself the control. Four treatments
> were carried out every 8 weeks in a double-blind, randomized
> fashion. Metric circumferential evaluations and photographic
> and ultrasonographic measurements throughout the study
> allowed for final judgment. A statistical evaluation
> concluded our study. RESULTS An overall reduction of local
> fat was obtained in 91.9% of the patients without
> statistically significant differences between the treated
> sides. Reduction values on the phosphatidylcholine/sodium
> deoxycholate-treated sides are in the order of 6.46%
> metrically and
> 36.87% ultrasonographically, whereas on the
> deoxycholate-treated sides they are in the order of
> 6.77% metrically and 36.06% ultrasonographically. Both
> treatments, at the dose used in the study, proved safe
> in the short term. The most common side effects were
> local and few, but were more pronounced on the
> deoxycholate-treated sides. No laboratory test was
> carried out. CONCLUSION Both treatments have shown
> moderate and equivalent efficacy in treating localized
> fat, with sodium deoxycholate having a slower
> postoperative resolution, suggesting that sodium
> deoxycholate could be sufficient by itself to
> determine fat cell destruction and that
> phosphatidylcholine could be useful for obtaining a
> later emulsification of the fat.
>
> ------------------------------------------------------------
> ----------------------
>
> Dermatol Surg
>
> Who loves ya. Tom
>
> Jesus Was A Vegetarian!http://jesuswasavegetarian.7h.com
>
> Man Is A Herbivore!http://tinyurl.com/a3cc3
>
> DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk