Lipids and krill oil

[Bigvince]

Altern Med Rev. 2004 Dec;9(4):420-8. Links Evaluation of
the effects of Neptune Krill Oil on the clinical course
of hyperlipidemia.Bunea R, El Farrah K, Deutsch L.
Department of Internal Medicine, McGill University,
Montreal, Quebec, Canada.

OBJECTIVE: To assess the effects of krill oil on blood lipids,
specifically total cholesterol, triglycerides, low-density
lipoprotein
(LDL), and high-density lipoprotein (HDL). METHODS: A
multi-center, three-month, prospective, randomized study
followed by a three-month, controlled follow-up of
patients treated with 1 g and 1.5 g krill oil daily.
Patients with hyperlipidemia able to maintain a healthy
diet and with blood cholesterol levels between 194 and
348 mg per dL were eligible for enrollment in the trial.
A sample size of 120 patients (30 patients per group) was
randomly assigned to one of four groups. Group A received
krill oil at a body mass index (BMI)-dependent daily
dosage of 2-3 g daily. Patients in Group B were given
1-1.5 g krill oil daily, and Group C was given fish oil
containing 180 mg eicosapentaenoic acid (EPA) and 120 mg
docosahexaenoic acid (DHA) per gram of oil at a dose of 3
g daily. Group D was given a placebo containing
microcrystalline cellulose. The krill oil used in this
study was Neptune Krill Oil, provided by Neptune
Technologies and Bioresources, Laval, Quebec, Canada.
OUTCOME MEASURES: Primary parameters tested (baseline and
90-day visit) were total blood cholesterol,
triglycerides, LDL, HDL, and glucose. RESULTS: Krill oil
1-3 g per day (BMI-dependent) was found to be effective
for the reduction of glucose, total cholesterol,
triglycerides, LDL, and HDL, compared to both fish oil
and placebo. CONCLUSIONS: The results of the present
study demonstrate within high levels of confidence that
krill oil is effective for the management of
hyperlipidemia by significantly reducing total
cholesterol, LDL, and triglycerides, and increasing HDL
levels. At lower and equal doses, krill oil was
significantly more effective than fish oil for the
reduction of glucose, triglycerides, and LDL levels.

PMID: 15656713 [PubMed - indexed for MEDLINE]

And no liver fuction test required .Impressive Thanks Vince

[Juhana Har]

bigvince wrote:
> Altern Med Rev. 2004 Dec;9(4):420-8. Links Evaluation of
> the effects of Neptune Krill Oil on the clinical course
> of hyperlipidemia.Bunea R, El Farrah K, Deutsch L.
> Department of Internal Medicine, McGill University,
> Montreal, Quebec, Canada.
>
> OBJECTIVE: To assess the effects of krill oil on blood
> lipids, specifically total cholesterol, triglycerides,
> low-density lipoprotein
> (LDL), and high-density lipoprotein (HDL). METHODS: A
> multi-center, three-month, prospective, randomized
> study followed by a three-month, controlled follow-up
> of patients treated with 1 g and 1.5 g krill oil daily.
> Patients with hyperlipidemia able to maintain a healthy
> diet and with blood cholesterol levels between 194 and
> 348 mg per dL were eligible for enrollment in the
> trial. A sample size of 120 patients (30 patients per
> group) was randomly assigned to one of four groups.
> Group A received krill oil at a body mass index
> (BMI)-dependent daily dosage of 2-3 g daily. Patients
> in Group B were given 1-1.5 g krill oil daily, and
> Group C was given fish oil containing 180 mg
> eicosapentaenoic acid (EPA) and 120 mg docosahexaenoic
> acid (DHA) per gram of oil at a dose of 3 g daily.
> Group D was given a placebo containing microcrystalline
> cellulose. The krill oil used in this study was Neptune
> Krill Oil, provided by Neptune Technologies and
> Bioresources, Laval, Quebec, Canada. OUTCOME MEASURES:
> Primary parameters tested (baseline and 90-day visit)
> were total blood cholesterol, triglycerides, LDL, HDL,
> and glucose. RESULTS: Krill oil 1-3 g per day
> (BMI-dependent) was found to be effective for the
> reduction of glucose, total cholesterol, triglycerides,
> LDL, and HDL, compared to both fish oil and placebo.
> CONCLUSIONS: The results of the present study
> demonstrate within high levels of confidence that krill
> oil is effective for the management of hyperlipidemia
> by significantly reducing total cholesterol, LDL, and
> triglycerides, and increasing HDL levels. At lower and
> equal doses, krill oil was significantly more effective
> than fish oil for the reduction of glucose,
> triglycerides, and LDL levels.
>
> PMID: 15656713 [PubMed - indexed for MEDLINE]
>
> And no liver fuction test required .Impressive

Here is the full study:

http://www.thorne.com/altmedrev/.fulltext/9/4/420.pdf

The results were impressive but it should be noticed that is
was a company study which makes the results less reliable.

--
Juhana

http://ruohikolla.blogspot.com/

[Jim Chinni]

bigvince <Vince.Miraglia@gmail.com> wrote in part:

>RESULTS: Krill oil 1-3 g per day (BMI-dependent) was found
>to be effective for the reduction of glucose, total
>cholesterol, triglycerides, LDL, and HDL, compared to both
>fish oil and placebo.

Reduced HDL? And no evidence at all of any benefits.
--
Jim Chinnis Warrenton, Virginia, USA

[Jim Chinni]

"Juhana Harju" <nope@mail.fi> wrote in part:

>The results were impressive but it should be noticed that is
>was a company study which makes the results less reliable.

But the company isn't a pharma, so it's good work. And it's
published in the Alternative Medicine Review instead of The
New England Journal of Medicine, so it's untainted.
--
Jim Chinnis Warrenton, Virginia, USA

[Juhana Har]

Jim Chinnis wrote:
> bigvince <Vince.Miraglia@gmail.com> wrote in part:
>
>> RESULTS: Krill oil 1-3 g per day (BMI-dependent) was found
>> to be effective for the reduction of glucose, total
>> cholesterol, triglycerides, LDL, and HDL, compared to both
>> fish oil and placebo.
>
> Reduced HDL? And no evidence at all of any benefits.

There is an error in the abstract. You can check it from the
full study. Actually krill oil increased HDL very efficiently.

--
Juhana

http://ruohikolla.blogspot.com/

[Juhana Har]

Jim Chinnis wrote:
> "Juhana Harju" <nope@mail.fi> wrote in part:
>
>> The results were impressive but it should be noticed that
>> is was a company study which makes the results less
>> reliable.
>
> But the company isn't a pharma, so it's good work. And it's
> published in the Alternative Medicine Review instead of The
> New England Journal of Medicine, so it's untainted.

I am not quite sure for whom did you aim your irony. Please
notice that I made the reservation.

--
Juhana

http://ruohikolla.blogspot.com/

[Jim Chinni]

"Juhana Harju" <nope@mail.fi> wrote in part:

>Jim Chinnis wrote:
>> bigvince <Vince.Miraglia@gmail.com> wrote in part:
>>
>>> RESULTS: Krill oil 1-3 g per day (BMI-dependent) was found
>>> to be effective for the reduction of glucose, total
>>> cholesterol, triglycerides, LDL, and HDL, compared to both
>>> fish oil and placebo.
>>
>> Reduced HDL? And no evidence at all of any benefits.
>
>There is an error in the abstract. You can check it from the
>full study. Actually krill oil increased HDL very
>efficiently.

I know. The authors just got it mixed up.

Still, no evidence of clinical benefit, only effects on
potential mediators of cardiovascular ills.

Note: I'm not opposed to krill oil.
--
Jim Chinnis Warrenton, Virginia, USA

[Jim Chinni]

"Juhana Harju" <nope@mail.fi> wrote in part:

>Jim Chinnis wrote:
>> "Juhana Harju" <nope@mail.fi> wrote in part:
>>
>>> The results were impressive but it should be noticed that
>>> is was a company study which makes the results less
>>> reliable.
>>
>> But the company isn't a pharma, so it's good work. And it's
>> published in the Alternative Medicine Review instead of The
>> New England Journal of Medicine, so it's untainted.
>
>I am not quite sure for whom did you aim your irony. Please
>notice that I made the reservation.

It wasn't aimed at you.
--
Jim Chinnis Warrenton, Virginia, USA

[Juhana Har]

Jim Chinnis wrote:
> "Juhana Harju" <nope@mail.fi> wrote in part:
>
>> Jim Chinnis wrote:
>>> bigvince <Vince.Miraglia@gmail.com> wrote in part:
>>>
>>>> RESULTS: Krill oil 1-3 g per day (BMI-dependent) was
>>>> found to be effective for the reduction of glucose, total
>>>> cholesterol, triglycerides, LDL, and HDL, compared to
>>>> both fish oil and placebo.
>>>
>>> Reduced HDL? And no evidence at all of any benefits.
>>
>> There is an error in the abstract. You can check it from
>> the full study. Actually krill oil increased HDL very
>> efficiently.
>
> I know. The authors just got it mixed up.
>
> Still, no evidence of clinical benefit, only effects on
> potential mediators of cardiovascular ills.

I agree. I would also like to see at least one independent
study to confirm the results.

> Note: I'm not opposed to krill oil.

And I am not very convinced of the benefits of krill oil until
I see some further studies.

--
Juhana

[William Wa]

In article <qj0ni3phl2v1ijn73905afgr8gnl6iad10@4ax.com>, Jim
Chinnis <jchinnis@SPAMalum.mit.edu> wrote:

> "Juhana Harju" <nope@mail.fi> wrote in part:
>
> >Jim Chinnis wrote:
> >> "Juhana Harju" <nope@mail.fi> wrote in part:
> >>
> >>> The results were impressive but it should be noticed
> >>> that is was a company study which makes the results less
> >>> reliable.
> >>
> >> But the company isn't a pharma, so it's good work. And
> >> it's published in the Alternative Medicine Review instead
> >> of The New England Journal of Medicine, so it's
> >> untainted.
> >
> >I am not quite sure for whom did you aim your irony. Please
> >notice that I made the reservation.
>
> It wasn't aimed at you.
> --
> Jim Chinnis Warrenton, Virginia, USA

Rumor has it Juhana has a new book.

Bill

--

S Jersey USA Zone 5 Shade

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in accordance with Title 17 U.S.C. Section 107, and is
strictly for the educational and informative purposes. This
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[Listener]

bigvince <Vince.Miraglia@gmail.com> wrote in
news:1194008403.940335.18410@ 19g2000hsx.googlegroups.com:

> Altern Med Rev. 2004 Dec;9(4):420-8. Links Evaluation of
> the effects of Neptune Krill Oil on the clinical course
> of hyperlipidemia.Bunea R, El Farrah K, Deutsch L.
> Department of Internal Medicine, McGill University,
> Montreal, Quebec, Canada.

What about the poor krill? Does no one speak for them?

[Juhana Har]

listener wrote:
> bigvince <Vince.Miraglia@gmail.com> wrote in
> news:1194008403.940335.18410@ 19g2000hsx.googlegroups.com:
>
>> Altern Med Rev. 2004 Dec;9(4):420-8. Links Evaluation of
>> the effects of Neptune Krill Oil on the clinical course of
>> hyperlipidemia.Bunea R, El Farrah K, Deutsch L. Department
>> of Internal Medicine, McGill University, Montreal, Quebec,
>> Canada.
>
> What about the poor krill? Does no one speak for them?

They are indeed an endangered species but not because of
human consumption but because they are overharvested to feed
farmed salmon.

http://tinyurl.com/yshcql

I think that the problem of sustainability of marine foods
should be addressed.

--
Juhana

http://ruohikolla.blogspot.com/