Ironjustic
Thu, Nov-01-07, 06:16
Brisket disease and portal hypertension. Coincidentally both
happen at high altitude.
<<snip>> In "doen=E7a do peito inchado" (brisket disease), the
liver values for iron very high. <<snip>>
High Alt Med Biol. 2004 Summer;5(2):156-70. Links Erratum in:
High Alt Med Biol. 2004 Winter;5(4):470. Syndromes of subacute
mountain sickness. Anand IS, Wu T. Heart Failure Program, VA
Medical Center, and University of Minnesota Medical School,
Minneapolis, 55417, USA. anand001@umn.edu
Two clinical syndromes, acute and chronic mountain sickness,
have traditionally been associated with high altitude.
Recently, two separate entities of subacute nature have been
described in infants and adults. In this paper, we review the
published literature on these conditions. Subacute infantile
mountain sickness is a condition seen predominantly in Han
Chinese infants living in Tibet, although it has been
described in other high altitude communities as well. It came
into prominence only after the large-scale migration of
Chinese population from the low altitude of mainland China to
the high altitudes of the Qinghai-Tibetan plateau. The
condition is characterized by features of severe hypoxic
pulmonary hypertension and heart failure. Pulmonary histology
is consistent with muscularization of the pulmonary
arterioles, but no intimal proliferation or plexiform lesions
are seen. The second syndrome, adult subacute mountain
sickness, has been described almost exclusively in Indian
soldiers living at extreme altitude for prolonged periods of
time. In this condition also, hypoxic pulmonary hypertension
appears to be the dominant factor responsible for severe
congestive heart failure. Both these conditions have several
similarities with brisket disease in cattle; hypoxic pulmonary
vasoconstriction plays an important role in the pathogenesis,
and removal from high altitude results in complete resolution.
Thus, it appears that both these syndromes are human
counterparts of brisket disease in cattle.
PMID: 15265337 [PubMed - indexed for MEDLINE]
--------------------------------------------------------------
---------------
Pesquisa Veterin=E1ria Brasileira Print ISSN 0100-736X
Abstract TOKARNIA, Carlos Hubinger, DOBEREINER, J=FCrgen,
MORAES, Sheila S. et al. Mineral deficiencies and imbalances
in cattle and sheep =BE a review of Brazilian studies made
between 1987 and 1998. Pesq. Vet. Bras., Apr./Jun. 1999,
vol.19, no.2, p.47-62. ISSN 0100-736X.
This review follows on from two previous ones on the subject
covering the periods from 1943 to 1976 and 1976 to 1987. They
are all based on the chemical analyses of liver or other
animal tissues or fluids and/ or experimentation, complemented
or not by analyses of pasture and soil samples. They do not
include studies based only on chemical analyses of plant and
soil samples. Regarding macroelements, noteworthy are the
studies on phosphorus deficiency, the most important mineral
deficiency shown previusly. Copper and cobalt deficiencies
were the most frequent microelement deficiencies. There were
several reports on copper poisoning in sheep. Subclinical
deficiency of zinc was frequently verified. Subclinical
manganese deficiency was rarely recognized and to the
contrary, elevated values of this element occasionaly were
found. There was little data on selenium, so its importance in
Brazil remains unclear; nutritional miopathy was diagnosed for
the first time in calves, but only once. Low iron values were
found in the liver samples of cattle affected by enzootic
hematuria. This is easily explained by the continuous loss of
blood leading to severe anemia. High iron values were found in
the liver samples from some areas; sometimes associated with
low copper values. Among the investigations made during the
last decade, special mention should be made of two diseases in
which the etiology has not yet been established. These are
"ronca" (snoring disease) and "doen=E7a do peito inchado"
(brisket disease), both of which have a chronic course in
adult cattle. In "ronca", liver copper is very low and iron
particularly high. Presumably the latter is caused by poor
utilization due to the copper deficiency. In "doen=E7a do
peito inchado", the liver values for manganese and cobalt were
low and those for iron very high. In this case, the high iron
probably comes from the severe liver congestion caused by the
chronic cardiac insufficiency seen in this disease. Mention
also should be made of "morte subita" (sudden death) in cattle
in the State of Rio Grande do Sul. In this case, liver copper
levels were extremely low and no poisonous plant could be
blamed. Congenital hypomyelinogenesis in calves was diagnosed
in the same area.The mineral deficiencies diagnosed during the
period of this review are shown on a map, together with the
respective bibliographic references.
Keywords : Mineral deficiencies; excesses of minerals; mineral
toxicities; mineral imbalances; cattle; sheep; Brazil.
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
happen at high altitude.
<<snip>> In "doen=E7a do peito inchado" (brisket disease), the
liver values for iron very high. <<snip>>
High Alt Med Biol. 2004 Summer;5(2):156-70. Links Erratum in:
High Alt Med Biol. 2004 Winter;5(4):470. Syndromes of subacute
mountain sickness. Anand IS, Wu T. Heart Failure Program, VA
Medical Center, and University of Minnesota Medical School,
Minneapolis, 55417, USA. anand001@umn.edu
Two clinical syndromes, acute and chronic mountain sickness,
have traditionally been associated with high altitude.
Recently, two separate entities of subacute nature have been
described in infants and adults. In this paper, we review the
published literature on these conditions. Subacute infantile
mountain sickness is a condition seen predominantly in Han
Chinese infants living in Tibet, although it has been
described in other high altitude communities as well. It came
into prominence only after the large-scale migration of
Chinese population from the low altitude of mainland China to
the high altitudes of the Qinghai-Tibetan plateau. The
condition is characterized by features of severe hypoxic
pulmonary hypertension and heart failure. Pulmonary histology
is consistent with muscularization of the pulmonary
arterioles, but no intimal proliferation or plexiform lesions
are seen. The second syndrome, adult subacute mountain
sickness, has been described almost exclusively in Indian
soldiers living at extreme altitude for prolonged periods of
time. In this condition also, hypoxic pulmonary hypertension
appears to be the dominant factor responsible for severe
congestive heart failure. Both these conditions have several
similarities with brisket disease in cattle; hypoxic pulmonary
vasoconstriction plays an important role in the pathogenesis,
and removal from high altitude results in complete resolution.
Thus, it appears that both these syndromes are human
counterparts of brisket disease in cattle.
PMID: 15265337 [PubMed - indexed for MEDLINE]
--------------------------------------------------------------
---------------
Pesquisa Veterin=E1ria Brasileira Print ISSN 0100-736X
Abstract TOKARNIA, Carlos Hubinger, DOBEREINER, J=FCrgen,
MORAES, Sheila S. et al. Mineral deficiencies and imbalances
in cattle and sheep =BE a review of Brazilian studies made
between 1987 and 1998. Pesq. Vet. Bras., Apr./Jun. 1999,
vol.19, no.2, p.47-62. ISSN 0100-736X.
This review follows on from two previous ones on the subject
covering the periods from 1943 to 1976 and 1976 to 1987. They
are all based on the chemical analyses of liver or other
animal tissues or fluids and/ or experimentation, complemented
or not by analyses of pasture and soil samples. They do not
include studies based only on chemical analyses of plant and
soil samples. Regarding macroelements, noteworthy are the
studies on phosphorus deficiency, the most important mineral
deficiency shown previusly. Copper and cobalt deficiencies
were the most frequent microelement deficiencies. There were
several reports on copper poisoning in sheep. Subclinical
deficiency of zinc was frequently verified. Subclinical
manganese deficiency was rarely recognized and to the
contrary, elevated values of this element occasionaly were
found. There was little data on selenium, so its importance in
Brazil remains unclear; nutritional miopathy was diagnosed for
the first time in calves, but only once. Low iron values were
found in the liver samples of cattle affected by enzootic
hematuria. This is easily explained by the continuous loss of
blood leading to severe anemia. High iron values were found in
the liver samples from some areas; sometimes associated with
low copper values. Among the investigations made during the
last decade, special mention should be made of two diseases in
which the etiology has not yet been established. These are
"ronca" (snoring disease) and "doen=E7a do peito inchado"
(brisket disease), both of which have a chronic course in
adult cattle. In "ronca", liver copper is very low and iron
particularly high. Presumably the latter is caused by poor
utilization due to the copper deficiency. In "doen=E7a do
peito inchado", the liver values for manganese and cobalt were
low and those for iron very high. In this case, the high iron
probably comes from the severe liver congestion caused by the
chronic cardiac insufficiency seen in this disease. Mention
also should be made of "morte subita" (sudden death) in cattle
in the State of Rio Grande do Sul. In this case, liver copper
levels were extremely low and no poisonous plant could be
blamed. Congenital hypomyelinogenesis in calves was diagnosed
in the same area.The mineral deficiencies diagnosed during the
period of this review are shown on a map, together with the
respective bibliographic references.
Keywords : Mineral deficiencies; excesses of minerals; mineral
toxicities; mineral imbalances; cattle; sheep; Brazil.
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk