more on vit D - lower dosage recommended

[Dawid Mich]

Excerpt from the article:

"Researchers from the European Institute of Oncology in Milan,
Italy, and the International Agency for Research on Cancer in
Lyon, France, reviewed 18 trials of more than 57,000 people.

The trials involved doses of vitamin D ranging from 300
international units (IUs) to 2,000 IUs. The average dose
was 528 IUs.

After a period of six years, the data showed that people who
took vitamin D supplements had a 7 percent lower risk of death
compared to people who did not take the supplements.

Further, according to the nine trials that collected blood
samples, people who took vitamin D supplements had a 1.4- to
5.2-fold higher level of vitamin D in their blood than those
who did not.

Because vitamin D can reduce the proliferation of cells, which
occurs in cancer, the researchers believe their finding could
lead to new drugs to fight cancer and other illnesses.

Vitamin D also helps your body to uptake calcium for
bone health.

The researchers recommend taking between 400 IUs and 600 IUs
of vitamin D daily. Your skin can also produce its own vitamin
D by getting moderate sun exposure each day."

source: http://articles.mercola.com/sites/articles/archive/20-
07/09/29/vitamin-d-the-secret-of-a-long-life.aspx

--
Dawid http://www.headache-migraine.net _Migraine headache
information_

[trigonomet]

> The researchers recommend taking between 400 IUs and 600 IUs
> of vitamin D daily. Your skin can also produce its own
> vitamin D by getting moderate sun exposure each day."
>

Sure some repeat thosed dated recommendation and often it is
not the researcher but the reporter or some other supposed
authority providing background. Many now recommend 800 to 1000
IU. Which is still too low but an improvement.

The 200, 400, and 600 recommendation is sorely dated.

[Bigvince]

On Sep 29, 7:43 am, trigonometry1...@gmail.com wrote:
> > The researchers recommend taking between 400 IUs and 600
> > IUs of vitamin D daily. Your skin can also produce its own
> > vitamin D by getting moderate sun exposure each day."
>
> Sure some repeat thosed dated recommendation and often it is
> not the researcher but the reporter or some other supposed
> authority providing background. Many now recommend 800 to
> 1000 IU. Which is still too low but an improvement.
>
> The 200, 400, and 600 recommendation is sorely dated.

Hi first the study as far as I can see was in no way
suggesting that a dose of vitamin d in the 200 to 400 range
was better than one in the 1200- 2000 range a range more in
line with current thinking on this.Hers the abstract

Vitamin D Supplementation and Total Mortality
A Meta-analysis of Randomized Controlled Trials

Philippe Autier, MD; Sara Gandini, PhD

Arch Intern Med. 2007;167:1730-1737.

Background Ecological and observational studies suggest that
low vitamin D status could be associated with higher mortality
from life- threatening conditions including cancer,
cardiovascular disease, and diabetes mellitus that account for
60% to 70% of total mortality in high-income countries. We
examined the risk of dying from any cause in subjects who
participated in randomized trials testing the impact of
vitamin D supplementation (ergocalciferol [vitamin D2] or
cholecalciferol [vitamin D3]) on any health condition.

Methods The literature up to November 2006 was searched
without language restriction using the following databases:
PubMed, ISI Web of Science (Science Citation Index Expanded),
EMBASE, and the Cochrane Library.

Results We identified 18 independent randomized controlled
trials, including 57 311 participants. A total of 4777 deaths
from any cause occurred during a trial size-adjusted mean of
5.7 years. Daily doses of vitamin D supplements varied from
300 to 2000 IU. The trial size- adjusted mean daily vitamin D
dose was 528 IU. In 9 trials, there was a 1.4- to 5.2-fold
difference in serum 25-hydroxyvitamin D between the
intervention and control groups. The summary relative risk for
mortality from any cause was 0.93 (95% confidence interval,
.87-0.99). There was neither indication for heterogeneity nor
indication for publication biases. The summary relative risk
did not change according to the addition of calcium
supplements in the intervention.

Conclusions Intake of ordinary doses of vitamin D supplements
seems to be associated with decreases in total mortality
rates. The relationship between baseline vitamin D status,
dose of vitamin D supplements, and total mortality rates
remains to be investigated. Population-based,
placebo-controlled randomized trials with total mortality as
the main end point should be organized for confirming these
findings. '

Thanks Vince

[Vernono O]

<trigonometry1972@gmail.com> wrote in message
news:1191066216.957232.121280@d55g2000hsg.googlegroups.com...
>
>> The researchers recommend taking between 400 IUs and 600
>> IUs of vitamin D daily. Your skin can also produce its own
>> vitamin D by getting moderate sun exposure each day."
>>
>
> Sure some repeat thosed dated recommendation and often it is
> not the researcher but the reporter or some other supposed
> authority providing background. Many now recommend 800 to
> 1000 IU. Which is still too low but an improvement.
>
> The 200, 400, and 600 recommendation is sorely dated.
>

SORELY, with no doubt.