Can vitamin D [the sunshine vitamin] reduce mortality rates?

[Bigvince]

Apparently so.

Vitamin D Supplementation and Total Mortality A Meta-analysis
of Randomized Controlled Trials

Philippe Autier, MD; Sara Gandini, PhD

Arch Intern Med. 2007;167:1730-1737.

Background Ecological and observational studies suggest that
low vitamin D status could be associated with higher mortality
from life- threatening conditions including cancer,
cardiovascular disease, and diabetes mellitus that account for
60% to 70% of total mortality in high-income countries. We
examined the risk of dying from any cause in subjects who
participated in randomized trials testing the impact of
vitamin D supplementation (ergocalciferol [vitamin D2] or
cholecalciferol [vitamin D3]) on any health condition.

Methods The literature up to November 2006 was searched
without language restriction using the following databases:
PubMed, ISI Web of Science (Science Citation Index Expanded),
EMBASE, and the Cochrane Library.

Results We identified 18 independent randomized controlled
trials, including 57 311 participants. A total of 4777 deaths
from any cause occurred during a trial size-adjusted mean of
5.7 years. Daily doses of vitamin D supplements varied from
300 to 2000 IU. The trial size- adjusted mean daily vitamin D
dose was 528 IU. In 9 trials, there was a 1.4- to 5.2-fold
difference in serum 25-hydroxyvitamin D between the
intervention and control groups. The summary relative risk for
mortality from any cause was 0.93 (95% confidence interval,
.87-0.99). There was neither indication for heterogeneity nor
indication for publication biases. The summary relative risk
did not change according to the addition of calcium
supplements in the intervention. ....."

Apparently so less than 600 IU of vitamin d :much less than
most experts in this field view as optimal reduced
mortality by 7 %

Thanks Vince

[Mr. Natura]

Yes, I already knew that supplementing with D3 was good for
you.

Nobody, but naked aborigines can depend on sunshine for their
vitamin D supply.

Another good reason to eat fatty cold-water fish and code
liver oil.

bigvince wrote:
> Apparently so.
>
> Vitamin D Supplementation and Total Mortality A
> Meta-analysis of Randomized Controlled Trials
>
> Philippe Autier, MD; Sara Gandini, PhD
>
>
> Arch Intern Med. 2007;167:1730-1737.
>
> Background Ecological and observational studies suggest that
> low vitamin D status could be associated with higher
> mortality from life- threatening conditions including
> cancer, cardiovascular disease, and diabetes mellitus that
> account for 60% to 70% of total mortality in high-income
> countries. We examined the risk of dying from any cause in
> subjects who participated in randomized trials testing the
> impact of vitamin D supplementation (ergocalciferol [vitamin
> D2] or cholecalciferol [vitamin D3]) on any health
> condition.
>
> Methods The literature up to November 2006 was searched
> without language restriction using the following databases:
> PubMed, ISI Web of Science (Science Citation Index
> Expanded), EMBASE, and the Cochrane Library.
>
> Results We identified 18 independent randomized controlled
> trials, including 57 311 participants. A total of 4777
> deaths from any cause occurred during a trial size-adjusted
> mean of 5.7 years. Daily doses of vitamin D supplements
> varied from 300 to 2000 IU. The trial size- adjusted mean
> daily vitamin D dose was 528 IU. In 9 trials, there was a
> 1.4- to 5.2-fold difference in serum 25-hydroxyvitamin D
> between the intervention and control groups. The summary
> relative risk for mortality from any cause was 0.93 (95%
> confidence interval, .87-0.99). There was neither indication
> for heterogeneity nor indication for publication biases. The
> summary relative risk did not change according to the
> addition of calcium supplements in the intervention. ....."
>
> Apparently so less than 600 IU of vitamin d :much less than
> most experts in this field view as optimal reduced
> mortality by 7 %
>
> Thanks Vince

[N-H-P]

On Oct 1, 10:48 pm, trigonometry1...@gmail.com wrote:
> The ratio of vitamin A to D in fish liver oil is wrong.
> Further while people see fish liver oil as a more natural
> supplement form, it is highly processed and has been thru a
> complex distillation process to regulate the levels of the
> vitamins and the standard chosen ratio is less than ideal
> for most in the populations of the modern first world. Find
> a vitamin D3 capsule and take it. Or maybe take your shirt
> off and take in some UV.
>
> On Oct 1, 7:36 am, "Mr. Natural-Health"
>
> <zx...@naturalhealthperspective.com> wrote:
> > Yes, I already knew that supplementing with D3 was good
> > for you.
>
> > Nobody, but naked aborigines can depend on sunshine for
> > their vitamin D supply.
>
> > Another good reason to eat fatty cold-water fish and code
> > liver oil.
>
> > bigvince wrote:
> > > Apparently so.
>
> > > Vitamin D Supplementation and Total Mortality A
> > > Meta-analysis of Randomized Controlled Trials
>
> > > Philippe Autier, MD; Sara Gandini, PhD
>
> > > Arch Intern Med. 2007;167:1730-1737.
>
> > > Background Ecological and observational studies suggest
> > > that low vitamin D status could be associated with
> > > higher mortality from life- threatening conditions
> > > including cancer, cardiovascular disease, and diabetes
> > > mellitus that account for 60% to 70% of total mortality
> > > in high-income countries. We examined the risk of dying
> > > from any cause in subjects who participated in
> > > randomized trials testing the impact of vitamin D
> > > supplementation (ergocalciferol [vitamin D2] or
> > > cholecalciferol [vitamin D3]) on any health condition.
>
> > > Methods The literature up to November 2006 was searched
> > > without language restriction using the following
> > > databases: PubMed, ISI Web of Science (Science Citation
> > > Index Expanded), EMBASE, and the Cochrane Library.
>
> > > Results We identified 18 independent randomized
> > > controlled trials, including 57 311 participants. A
> > > total of 4777 deaths from any cause occurred during a
> > > trial size-adjusted mean of 5.7 years. Daily doses of
> > > vitamin D supplements varied from 300 to 2000 IU. The
> > > trial size- adjusted mean daily vitamin D dose was 528
> > > IU. In 9 trials, there was a 1.4- to 5.2-fold difference
> > > in serum 25-hydroxyvitamin D between the intervention
> > > and control groups. The summary relative risk for
> > > mortality from any cause was 0.93 (95% confidence
> > > interval, .87-0.99). There was neither indication for
> > > heterogeneity nor indication for publication biases. The
> > > summary relative risk did not change according to the
> > > addition of calcium supplements in the intervention.
> > > ....."
>
> > > Apparently so less than 600 IU of vitamin d :much less
> > > than most experts in this field view as optimal reduced
> > > mortality by 7 %

You can supplement cod liver oil, you know. :)

[Tc]

On Sep 28, 12:02 pm, bigvince <Vince.Mirag...@gmail.com>
wrote:
> Apparently so.
>
> Vitamin D Supplementation and Total Mortality A
> Meta-analysis of Randomized Controlled Trials
>
> Philippe Autier, MD; Sara Gandini, PhD
>
> Arch Intern Med. 2007;167:1730-1737.
>
> Background Ecological and observational studies suggest that
> low vitamin D status could be associated with higher
> mortality from life- threatening conditions including
> cancer, cardiovascular disease, and diabetes mellitus that
> account for 60% to 70% of total mortality in high-income
> countries. We examined the risk of dying from any cause in
> subjects who participated in randomized trials testing the
> impact of vitamin D supplementation (ergocalciferol [vitamin
> D2] or cholecalciferol [vitamin D3]) on any health
> condition.
>
> Methods The literature up to November 2006 was searched
> without language restriction using the following databases:
> PubMed, ISI Web of Science (Science Citation Index
> Expanded), EMBASE, and the Cochrane Library.
>
> Results We identified 18 independent randomized controlled
> trials, including 57 311 participants. A total of 4777
> deaths from any cause occurred during a trial size-adjusted
> mean of 5.7 years. Daily doses of vitamin D supplements
> varied from 300 to 2000 IU. The trial size- adjusted mean
> daily vitamin D dose was 528 IU. In 9 trials, there was a
> 1.4- to 5.2-fold difference in serum 25-hydroxyvitamin D
> between the intervention and control groups. The summary
> relative risk for mortality from any cause was 0.93 (95%
> confidence interval, .87-0.99). There was neither indication
> for heterogeneity nor indication for publication biases. The
> summary relative risk did not change according to the
> addition of calcium supplements in the intervention. ....."
>
> Apparently so less than 600 IU of vitamin d :much less than
> most experts in this field view as optimal reduced
> mortality by 7 %
>
> Thanks Vince

Try out your mortality rate without any vitamin D in
your diet.

[Juhana Har]

N-H-P wrote:
> On Oct 1, 10:48 pm, trigonometry1...@gmail.com wrote:
>> The ratio of vitamin A to D in fish liver oil is wrong.
>> Further while people see fish liver oil as a more natural
>> supplement form, it is highly processed and has been thru a
>> complex distillation process to regulate the levels of the
>> vitamins and the standard chosen ratio is less than ideal
>> for most in the populations of the modern first world. Find
>> a vitamin D3 capsule and take it. Or maybe take your shirt
>> off and take in some UV.
>>
>> On Oct 1, 7:36 am, "Mr. Natural-Health"
>>
>> <zx...@naturalhealthperspective.com> wrote:
>>> Yes, I already knew that supplementing with D3 was good
>>> for you.
>>
>>> Nobody, but naked aborigines can depend on sunshine for
>>> their vitamin D supply.
>>
>>> Another good reason to eat fatty cold-water fish and code
>>> liver oil.
>>
>>> bigvince wrote:
>>>> Apparently so.
>>
>>>> Vitamin D Supplementation and Total Mortality A
>>>> Meta-analysis of Randomized Controlled Trials
>>
>>>> Philippe Autier, MD; Sara Gandini, PhD
>>
>>>> Arch Intern Med. 2007;167:1730-1737.
>>
>>>> Background Ecological and observational studies suggest
>>>> that low vitamin D status could be associated with higher
>>>> mortality from life- threatening conditions including
>>>> cancer, cardiovascular disease, and diabetes mellitus
>>>> that account for 60% to 70% of total mortality in
>>>> high-income countries. We examined the risk of dying from
>>>> any cause in subjects who participated in randomized
>>>> trials testing the impact of vitamin D supplementation
>>>> (ergocalciferol [vitamin D2] or cholecalciferol [vitamin
>>>> D3]) on any health condition.
>>
>>>> Methods The literature up to November 2006 was searched
>>>> without language restriction using the following
>>>> databases: PubMed, ISI Web of Science (Science Citation
>>>> Index Expanded), EMBASE, and the Cochrane Library.
>>
>>>> Results We identified 18 independent randomized
>>>> controlled trials, including 57 311 participants. A total
>>>> of 4777 deaths from any cause occurred during a trial
>>>> size-adjusted mean of 5.7 years. Daily doses of vitamin D
>>>> supplements varied from 300 to 2000 IU. The trial size-
>>>> adjusted mean daily vitamin D dose was 528 IU. In 9
>>>> trials, there was a 1.4- to 5.2-fold difference in serum
>>>> 25-hydroxyvitamin D between the intervention and control
>>>> groups. The summary relative risk for mortality from any
>>>> cause was 0.93 (95% confidence interval, .87-0.99). There
>>>> was neither indication for heterogeneity nor indication
>>>> for publication biases. The summary relative risk did not
>>>> change according to the addition of calcium supplements
>>>> in the intervention. ....."
>>
>>>> Apparently so less than 600 IU of vitamin d :much less
>>>> than most experts in this field view as optimal reduced
>>>> mortality by 7 %
>
> You can supplement cod liver oil, you know.

It appears that you have not been reading this group recently.
There are risks in cod liver oil use as it has a high content
of retinol (vitamin A). That has a detrimental effect on bone.

--
Juhana