Fatty diet can harm female fertility

[Samuel]

http://www.hindustantimes.com/StoryPage/StoryPage.aspx?id=62b8ad91-cb89-4613-beed-42f76b5e4fbe&MatchID1=4504&TeamID1=2&TeamID2=6&MatchType1=2&SeriesID1=1125&PrimaryID=4504&Headline=Fatty+diet+can+harm+female+fertility

Fatty diet can harm female fertility
Melbourne, August 24, 2007
Last Updated: 17:56 IST(24/8/2007)

Researchers have given women yet another reason to lose all that extra flab by finding that fat can damage eggs in the ovaries.

The study, by a team of researchers from the University of Adelaide led by PhD researcher Cadence Minge, was conducted on pregnant mice.

While conducting their study the researchers noted that a fatty diet stops eggs from developing into healthy embryos, thereby affecting fertility.

"As a result, when fertilised, these eggs are not able to undergo normal, healthy development into embryos," News.com.au quoted Dr Minge, as telling the AAP.

"We hope our findings will encourage women to consider carefully the impact of their lifestyle choices on their own future and that of their children," she added.

However, the researchers also found a way to completely reverse the effects, thus enabling the eggs to develop into healthy embryos.

This was done by using the diabetes drug Avandia.

Using the drug the boffins selectively targeted a protein called peroxisome proliferator-activated receptor gamma (PPARg) and found they could undo the damage caused.

"The drug enables us to switch on the protein, thereby changing the way in which the ovaries sense and respond to fats," Minge said.

"Embryo development rates are restored, and the cellular differentiation of the early embryo is improved," she added.

However, Dr Minge also warned women that Avandia is not a safe treatment option for obese, infertile women at this stage.

"Also, the drug itself can have possible harmful side-effects, and more research is needed to find other, safer ways of activating the protein," she said.

[Calianna]

Researchers have given women yet another reason to lose all that extra flab by finding that fat can damage eggs in the ovaries.

It's being fat that causes the problem?

While conducting their study the researchers noted that a fatty diet stops eggs from developing into healthy embryos, thereby affecting fertility.



Oh wait, it's the fatty diet?'



They need to make up their minds.


And more to the point, is it a fatty high carb diet? Or a fatty low carb diet? And does it even hold true in humans? or is it just mice?

[ojoj]

I was wondering all that too!!???!!

[waywardsis]

The usual question applies...what were the mice eating?

Women have been getting pregnant for millenia on a diet that includes natural fats. I imagine here they're talking about "fatty" foods like pastries and Mickey D's?

[Groggy60]

Interchanging being fat with a fatty diet is just stupid. Eating fat has nothing to do with a diabetes drug, being fat certainly does.

[Mallory08]

haha ok if this is true wouldnt ALL of our ancestors have not been fertile i mean seriously talk about a high fat diet... I LOVE FAT haha at least eatting it

[Wifezilla]

Interchanging being fat with a fatty diet is just stupid.

Tell that to the Kimtologists!

[Lisa N]

The usual question applies...what were the mice eating?


And, more to the point, what are mice designed to eat normally?
It's kind of like feeding meat to rabbits to prove that eating meat is bad for you. Hello! Rabbits are not meat eaters, so why should it surprise anyone that they don't fare well on a diet of meat?
A normal rat/mouse diet is typically lower in fat and protein, higher in carbs.

[glennette]

Does this mean that everyone can throw out their birth control pills now and replace them with a nice diet of fat?

If this were true neither of my step-grandmothers would have had so many children (1 had 9 children and the other had 12)
This in a day when low fat was unheard of and milk came whole with cream on top, butter was always on the table, lard and bacon grease was used for cooking, and no one would ever think of throwing away the skin from thier poultry or buying lean meat.

Scientists like this should have their degrees revoked.