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Ironjustic
Thu, Jan-18-07, 06:15
Dietary glycemic load, whole grains, and systemic inflammation
in diabetes: the epidemiological evidence. Qi L, Hu FB Curr
Opin Lipidol. 2007 Feb ; 18(1): 3-8

PURPOSE OF REVIEW: The aim of this article is to present
recent findings from epidemiological studies on the effects of
dietary glycemic load and whole grain foods on systemic
inflammation in diabetic patients and to postulate potential
mechanisms. RECENT FINDINGS: Diets low in glycemic index/load
or high in whole grain products have been associated with
decreased concentrations of inflammatory markers and increased
adiponectin levels among diabetic patients. These associations
appear to be independent of body weight, glycemic control, and
other cardiovascular risk factors. The protective effects of
low glycemic load and high whole grains on systemic
inflammation may be explained, in part, by reduction in
hyperglycemia-induced overproduction of oxidative stress and
by amelioration in insulin resistance, adiposity,
dyslipidemia, and hypertension. SUMMARY: Diets low in glycemic
load and high in whole grains may have a protective effect
against systemic inflammation in diabetic patients. Such diets
can be recommended to diabetic patients for the prevention of
cardiovascular complications.

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