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Kumar
Sat, Nov-25-06, 06:15
Hello,

Bile is a thick digestive fluid secreted by the liver and
stored in the gallbladder. It facilitates digestion by
breaking down fats into fatty acids, which can be absorbed by
the digestive tract.Bile contains mostly cholesterol, bile
acids (also called bile salts), and bilirubin (a breakdown
product of hemoglobin). Bile also contains very small amounts
of excreted copper and other metals.Most of the bile is
reabsorbed.

The following links indicate that high cholesterol diet may
increase bile flow:-

Secretion into bile is a major route for eliminating
cholesterol. Free cholesterol is virtually insoluble in
aqueous solutions, but in bile, it is made soluble by bile
acids and lipids like lethicin. Gallstones, most of which are
composed predominantly of cholesterol, result from processes
that allow cholesterol to precipitate from solution in bile.
http://www.vivo.colostate.edu/hbooks/pathphys/digestion/liver-
/bile.html

"The high cholesterol, egg yolk diet caused the secretion of
an "abnormal bile" which led to precipitation of cholesterol
from micellar solution. The increased bile cholesterol
relative to bile acid and phospholipid favored stone
formation. This dietary induction of cholesterol gallstones
provided a unique animal model, in part but not completely
analogous to human cholelithiasis.http://www.pubmedcentral.ni-
h.gov/articlerender.fcgi?artid=292287&tools=bot

A number of metabolic studies indicated that the patient had
several compensatory mechanisms in place which enabled him
to maintain normal blood cholesterol concentrations in the
face of longstanding and massive cholesterol intake: http:/-
/www.vivo.colostate.edu/hbooks/pathphys/digestion/liver/eat-
eggs.html "

As such, can we relate comparatively more quantity of bile
flow, its reabsorption and more excretion in intestines with
fats having high cholesterols than with fats low or nil in
cholesterols?

Can low cholesterol diet impact normal bile flow, its
reabsorption and excretion--resulting into some health
problem?

Can cholesterol's absorption, synthesis and excretion be
effected by cholesterol's levels in body?

Best wishes.