Ironjustic
Sun, Oct-01-06, 06:17
Treatment for hypercholesterolemia Document Type and Number:
United States Patent 5231090 Link to this Page:
http://www.freepatentsonline.com/5231090.html Abstract: The
present invention relates to a method of modifying serum
cholesterol levels in a mammal by topically administering to
the skin of the mammal an effective amount of at least one
phospholipid. Atherosclerosis, and related complications, can
be treated, or prevented, using the present method
EXAMPLE III
BK, a 39 year old man who was in apparent good health
although slightly
overweight, became concerned about his elevated serum
cholesterol level. Fasting blood samples were taken in three
consecutive weeks, and
the results showed serum cholesterol consistently above 290
mg/dl. He was given the following instruction:
1) Take a hot shower in the evening, and dry your skin
with a towel.
2) Apply the solution given to you to your skin and rub it in
well, to cover your legs, arms, the abdomen and the back.
Use all the solution, and spread it to cover all your body.
3) To enhance percutaneous absorption, wrap your legs with a
thin plastic film, e.g. Saran Wrap, and fix the wrapping
with a tape or an Ace bandage.
4) Rest or take a nap, and wait for at least 2 hours before
washing off
the unabsorbed material on your skin.
The solution given him for each application was 12.5 ml of
Formula M-23-90 which has the following composition:
______________________________________
Formula M-23-9 (Total volume 78 ml)
______________________________________
Soy lecithin 25 gm BHT 0.2 gm Ethanol 25 ml Isopropanol 18
ml Distilled water 18 ml
______________________________________
BK returned each week or 10 days for analysis of fasting blood
lipid profile. His serum cholesterol and low density
lipoproteins showed definite reductions after each treatment
with Formula M-23-90. He reported no undesirable effects. A
summary of his lipid profiles is shown in the following table
______________________________________
BK LIPID PROFILE
(mg/dl of serum) Day SC TG HDL VLDL LDL
______________________________________
1 292 356 34 98 160 9 295 311 42 108 145 16 294 167
40 56 198 16 Treatment with Formula M-23-90 24 262
263 35 52 175 24 Treatment with Formula M-23-90 35
242 248 37 81 124 35 Treatment with Formula M-23-90
42 236 257 38 72 126
______________________________________
Abbreviations are: SC, serum cholesterol; TG, serum
triglycerides; HDL,
high density lipoproteins; VLDL, very low density
lipoproteins; LDL, low density lipoproteins.
The entire contents of all references cited hereinabove are
hereby incorporated by reference.
While the foregoing invention has been described in some
detail for purposes of clarity and understanding, it will be
clear to one skilled in the art from a reading of this
disclosure that various changes in form and detail can be made
without departing from the true scope of the invention.
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
United States Patent 5231090 Link to this Page:
http://www.freepatentsonline.com/5231090.html Abstract: The
present invention relates to a method of modifying serum
cholesterol levels in a mammal by topically administering to
the skin of the mammal an effective amount of at least one
phospholipid. Atherosclerosis, and related complications, can
be treated, or prevented, using the present method
EXAMPLE III
BK, a 39 year old man who was in apparent good health
although slightly
overweight, became concerned about his elevated serum
cholesterol level. Fasting blood samples were taken in three
consecutive weeks, and
the results showed serum cholesterol consistently above 290
mg/dl. He was given the following instruction:
1) Take a hot shower in the evening, and dry your skin
with a towel.
2) Apply the solution given to you to your skin and rub it in
well, to cover your legs, arms, the abdomen and the back.
Use all the solution, and spread it to cover all your body.
3) To enhance percutaneous absorption, wrap your legs with a
thin plastic film, e.g. Saran Wrap, and fix the wrapping
with a tape or an Ace bandage.
4) Rest or take a nap, and wait for at least 2 hours before
washing off
the unabsorbed material on your skin.
The solution given him for each application was 12.5 ml of
Formula M-23-90 which has the following composition:
______________________________________
Formula M-23-9 (Total volume 78 ml)
______________________________________
Soy lecithin 25 gm BHT 0.2 gm Ethanol 25 ml Isopropanol 18
ml Distilled water 18 ml
______________________________________
BK returned each week or 10 days for analysis of fasting blood
lipid profile. His serum cholesterol and low density
lipoproteins showed definite reductions after each treatment
with Formula M-23-90. He reported no undesirable effects. A
summary of his lipid profiles is shown in the following table
______________________________________
BK LIPID PROFILE
(mg/dl of serum) Day SC TG HDL VLDL LDL
______________________________________
1 292 356 34 98 160 9 295 311 42 108 145 16 294 167
40 56 198 16 Treatment with Formula M-23-90 24 262
263 35 52 175 24 Treatment with Formula M-23-90 35
242 248 37 81 124 35 Treatment with Formula M-23-90
42 236 257 38 72 126
______________________________________
Abbreviations are: SC, serum cholesterol; TG, serum
triglycerides; HDL,
high density lipoproteins; VLDL, very low density
lipoproteins; LDL, low density lipoproteins.
The entire contents of all references cited hereinabove are
hereby incorporated by reference.
While the foregoing invention has been described in some
detail for purposes of clarity and understanding, it will be
clear to one skilled in the art from a reading of this
disclosure that various changes in form and detail can be made
without departing from the true scope of the invention.
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk