Soy protein and lecithin in type 2 diabetic patients with hyperlipidemia

[Ironjustic]

Effects of soybean D-LeciVita product on serum lipids and
fatty acid composition in type 2 diabetic patients with
hyperlipidemia. Ristic Medic D, Ristic V, Arsic A, Postic M,
Ristic G, Blazencic Mladenovic V, Tepsic J Nutr Metab
Cardiovasc Dis. 2006 Sep ; 16(6): 395-404

BACKGROUND AND AIM: Hyperlipidemia is one of the major risk
factors of cardiovascular complication in diabetes. High
intake of soy product has been suggested to prevent
cardiovascular disease. The purpose of this study was to
evaluate if dietary supplement of soybean D-LeciVita product,
rich in polyunsaturated phospholipids (with 12% lecithin, 35%
soy protein) affects serum lipids and serum and erythrocyte
phospholipid fatty acid composition in type 2 diabetic
patients. METHODS AND RESULTS: Forty-seven patients (men and
post-menopausal women) with isolated hypertriglyceridemia
(IHTG) and combined hyperlipidemia (CHL), aged 43-70 years,
were given 15g of D-LeciVita powder as a water suspension in a
single evening dose during the follow-up period of 12 weeks.
Patients kept their diabetic diet relatively constant.
Treatment was associated with a significant (p < or =3D 0.001)
decrease in serum total cholesterol and triglyceride levels by
12% and 22%, respectively. LDL-cholesterol decreased by 16%
and HDL-cholesterol increased by 11% (p < or =3D 0.001). Our
study shows a 27% decrease in LDL-cholesterol (p < or =3D
0.001) and a 12% increase in HDL-cholesterol (p < or =3D 0.01)
in CHL type 2 diabetic patients. Triglyceride levels decreased
in type 2 diabetic patients with IHTG and CHL by 29% and 13%,
respectively (p < or =3D 0.01 and p < or =3D 0.05). Our
results show decrease in SFA and increase in n-6 and n-3 PUFA
in serum and erythrocyte phospholipids. SFA decreased and n-3
PUFA increased in serum and erythrocyte phospholipids in IHTG
and CHL groups. CONCLUSION: The present study indicated that
added to a regular diet, soybean D-LeciVita product
(combination of soy protein and lecithin) is associated not
only with lipid-lowering effects but also with more favorable
serum phospholipids fatty acid profile in type 2 diabetic
patients with hyperlipidemia.

Abstract =B7 PubMed FullText =B7 SFX =B7 GS Clip Export
InterDB =B7 Terms Related =B7 Graph Cites =B7 Scopus =B7 Tag
10.1016/j.numecd.2005.06.008

Who loves ya. Tom

Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com

Man Is A Herbivore! http://tinyurl.com/a3cc3

DEAD PEOPLE WALKING=20 http://tinyurl.com/zk9fk

[Bob Arnold]

A study comparing the effects of fish protein to soy and
casein on lipid metabolism in rats was posted in another
group.

"Although the cholesterol-lowering effect of soy protein
compared with casein is well known, only a few studies have
reported a hypolipidemic effect of fish protein."

Fish protein did well, and so did soy, but "the mechanism for
the cholesterol-lowering effect of [fish protein] is different
from that of soy." http://pmid.us/full:15173391

There's this one too: "Prevention of skeletal muscle insulin
resistance by dietary cod protein in high fat-fed rats."
http://pmid.us/full:11404223

In article
<1159380008.762954.131440@i3g2000cwc.googlegroups.com>,
"ironjustice@aol.com" <ironjustice@aol.com> wrote:

> Effects of soybean D-LeciVita product on serum lipids and
> fatty acid composition in type 2 diabetic patients with
> hyperlipidemia. Ristic Medic D, Ristic V, Arsic A, Postic M,
> Ristic G, Blazencic Mladenovic V, Tepsic J Nutr Metab
> Cardiovasc Dis. 2006 Sep ; 16(6): 395-404
>
> BACKGROUND AND AIM: Hyperlipidemia is one of the major risk
> factors of cardiovascular complication in diabetes. High
> intake of soy product has been suggested to prevent
> cardiovascular disease. The purpose of this study was to
> evaluate if dietary supplement of soybean D-LeciVita
> product, rich in polyunsaturated phospholipids (with 12%
> lecithin, 35% soy protein) affects serum lipids and serum
> and erythrocyte phospholipid fatty acid composition in type
> 2 diabetic patients. METHODS AND RESULTS: Forty-seven
> patients (men and post-menopausal women) with isolated
> hypertriglyceridemia (IHTG) and combined hyperlipidemia
> (CHL), aged 43-70 years, were given 15g of D-LeciVita powder
> as a water suspension in a single evening dose during the
> follow-up period of 12 weeks. Patients kept their diabetic
> diet relatively constant. Treatment was associated with a
> significant (p < or = 0.001) decrease in serum total
> cholesterol and triglyceride levels by 12% and 22%,
> respectively. LDL-cholesterol decreased by 16% and
> HDL-cholesterol increased by 11% (p < or = 0.001). Our study
> shows a 27% decrease in LDL-cholesterol (p < or = 0.001) and
> a 12% increase in HDL-cholesterol (p < or = 0.01) in CHL
> type 2 diabetic patients. Triglyceride levels decreased in
> type 2 diabetic patients with IHTG and CHL by 29% and 13%,
> respectively (p < or = 0.01 and p < or = 0.05). Our results
> show decrease in SFA and increase in n-6 and n-3 PUFA in
> serum and erythrocyte phospholipids. SFA decreased and n-3
> PUFA increased in serum and erythrocyte phospholipids in
> IHTG and CHL groups. CONCLUSION: The present study indicated
> that added to a regular diet, soybean D-LeciVita product
> (combination of soy protein and lecithin) is associated not
> only with lipid-lowering effects but also with more
> favorable serum phospholipids fatty acid profile in type 2
> diabetic patients with hyperlipidemia.
>
>
> Abstract · PubMed FullText · SFX · GS Clip Export InterDB ·
> Terms Related · Graph Cites · Scopus · Tag
> 10.1016/j.numecd.2005.06.008
>
>
> Who loves ya. Tom
>
>
> Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
>
>
> Man Is A Herbivore! http://tinyurl.com/a3cc3
>
>
> DEAD PEOPLE WALKING http://tinyurl.com/zk9fk