Ironjustic
Sat, Sep-23-06, 17:16
J Soc Gynecol Investig. 2006 Sep 19; [Epub ahead of print]
Links Oxidant/Antioxidant Status of Placenta, Blood, and Cord
Blood Samples
>From Pregnant Women Supplemented With Iron.Devrim E, Tarhan
>I, Erguder
IB, Durak I. Ankara University School of Medicine, Department
of Biochemistry, Ankara, Turkey.
OBJECTIVE: In this study, it was aimed to investigate
oxidant/antioxidant status in placenta and in blood and cord
blood samples from pregnant women supplemented with iron
during pregnancy. METHODS: For this purpose, 27 pregnant women
at admission for delivery participated in the study. Fifteen
of them did not take iron tablets and the others took oral
iron supplements during pregnancy. Following delivery, part of
the placenta and blood and cord blood samples were taken from
the mothers. In these samples, oxidant parameters
(malondialdehyde [MDA] levels and xanthine oxidase [XO]
activities) and antioxidant parameters (antioxidant potential
[AOP] values, superoxide dismutase [SOD], catalase [CAT] and
glutathione peroxidase [GSH-Px] activities) were studied.
RESULTS: It was found that MDA level and SOD activities
increased significantly in the placentas from the
iron-supplemented group as compared with those from the
control group. We also observed that activities of SOD and XO
enzymes in maternal erythrocytes, XO in cord blood
erythrocytes and GSH-Px activities in cord blood plasma
decreased significantly. However, activities of CAT and GSH-Px
enzymes in cord blood erythrocytes and MDA levels in maternal
plasma increased in the iron-supplemented group as compared
with those from the control group. CONCLUSION: Increased MDA
levels in the maternal plasma and the placenta in the
iron-supplemented group suggests that iron supplementation may
contribute to increased oxidative stress in women taking iron
supplements during pregnancy.
PMID: 16990032 [PubMed - as supplied by publisher]
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
Links Oxidant/Antioxidant Status of Placenta, Blood, and Cord
Blood Samples
>From Pregnant Women Supplemented With Iron.Devrim E, Tarhan
>I, Erguder
IB, Durak I. Ankara University School of Medicine, Department
of Biochemistry, Ankara, Turkey.
OBJECTIVE: In this study, it was aimed to investigate
oxidant/antioxidant status in placenta and in blood and cord
blood samples from pregnant women supplemented with iron
during pregnancy. METHODS: For this purpose, 27 pregnant women
at admission for delivery participated in the study. Fifteen
of them did not take iron tablets and the others took oral
iron supplements during pregnancy. Following delivery, part of
the placenta and blood and cord blood samples were taken from
the mothers. In these samples, oxidant parameters
(malondialdehyde [MDA] levels and xanthine oxidase [XO]
activities) and antioxidant parameters (antioxidant potential
[AOP] values, superoxide dismutase [SOD], catalase [CAT] and
glutathione peroxidase [GSH-Px] activities) were studied.
RESULTS: It was found that MDA level and SOD activities
increased significantly in the placentas from the
iron-supplemented group as compared with those from the
control group. We also observed that activities of SOD and XO
enzymes in maternal erythrocytes, XO in cord blood
erythrocytes and GSH-Px activities in cord blood plasma
decreased significantly. However, activities of CAT and GSH-Px
enzymes in cord blood erythrocytes and MDA levels in maternal
plasma increased in the iron-supplemented group as compared
with those from the control group. CONCLUSION: Increased MDA
levels in the maternal plasma and the placenta in the
iron-supplemented group suggests that iron supplementation may
contribute to increased oxidative stress in women taking iron
supplements during pregnancy.
PMID: 16990032 [PubMed - as supplied by publisher]
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk