Ironjustic
Sun, Aug-13-06, 06:15
http://www.indianpediatrics.net/oct2005/oct-998-1005.htm
Indian Pediatrics 2005; 42:998-1005
Transcutaneous Absorption of Topically Massaged Oil in
Neonates
Kirti Solanki, Manoj Matnani, +Mrudula Kale, +Kalpana Joshi,
Ashish Bavdekar, Sheila Bhave and Anand Pandit
>From the *Department of Pediatrics, KEM Hospital, Pune 411
>011, India
and +School of Health Sciences, University of Pune, Pune 411
007, India.
Address for Correspondence : Dr. Sheila Bhave, Department of
Pediatrics, KEM Hospital, Pune 411 011, India. E-mail:
kemhrc@vsnl.com
Abstract
Objective: To study the transcutaneous absorption of
traditionally massaged oil in newborns and to specifically
compare the effects of (i) essential fatty acid (EFA) rich -
safflower oil and (ii) saturated fat rich coconut oil, on
fatty acid profiles of massaged babies. Design: A short term
randomised controlled study. Setting: Tertiary care NICU of a
large teaching hospital and a research laboratory of a
University complex. Methods: 120 study babies were randomly
assigned to three oil groups (i) safflower oil (n = 40) (ii)
coconut oil (n = 40) and (iii) no oil controls (n = 40). In
each group, babies were selected in three subsets as per their
gestational ages viz., (a) <34weeks, (b) 34-37 weeks, (c) > 37
weeks. 5 mL of the designated oil was massaged four times a
day (6hrly) for five days under controlled conditions of
temperature and feeding. Pre and post oil massage samples of
blood were analysed for triglycerides and fatty acid profiles
using gas chromatography. Results: Post oil triglyceride
values were significantly raised in both the oil groups and
also in controls. However, the quantum of rise was
significantly higher in oil groups as compared to controls (p
<0.05). Fatty acid profiles (gas chromatography) showed
significant rise in EFAs (linolenic acid and arachidonic acid)
in safflower oil group and saturated fats in coconut oil group
(p <0.05). Changes were more evident in term babies. There
were no side effects associated with the massage. Conclusion:
This study shows that topically applied oil can be absorbed in
neonates and is probably available for nutritional purposes.
The fatty acid constituents of the oil can influence the
changes in the fatty acid profiles of the massaged babies.
Key words: Fatty acid profile, Topical absorption,
Traditional oil .
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
Indian Pediatrics 2005; 42:998-1005
Transcutaneous Absorption of Topically Massaged Oil in
Neonates
Kirti Solanki, Manoj Matnani, +Mrudula Kale, +Kalpana Joshi,
Ashish Bavdekar, Sheila Bhave and Anand Pandit
>From the *Department of Pediatrics, KEM Hospital, Pune 411
>011, India
and +School of Health Sciences, University of Pune, Pune 411
007, India.
Address for Correspondence : Dr. Sheila Bhave, Department of
Pediatrics, KEM Hospital, Pune 411 011, India. E-mail:
kemhrc@vsnl.com
Abstract
Objective: To study the transcutaneous absorption of
traditionally massaged oil in newborns and to specifically
compare the effects of (i) essential fatty acid (EFA) rich -
safflower oil and (ii) saturated fat rich coconut oil, on
fatty acid profiles of massaged babies. Design: A short term
randomised controlled study. Setting: Tertiary care NICU of a
large teaching hospital and a research laboratory of a
University complex. Methods: 120 study babies were randomly
assigned to three oil groups (i) safflower oil (n = 40) (ii)
coconut oil (n = 40) and (iii) no oil controls (n = 40). In
each group, babies were selected in three subsets as per their
gestational ages viz., (a) <34weeks, (b) 34-37 weeks, (c) > 37
weeks. 5 mL of the designated oil was massaged four times a
day (6hrly) for five days under controlled conditions of
temperature and feeding. Pre and post oil massage samples of
blood were analysed for triglycerides and fatty acid profiles
using gas chromatography. Results: Post oil triglyceride
values were significantly raised in both the oil groups and
also in controls. However, the quantum of rise was
significantly higher in oil groups as compared to controls (p
<0.05). Fatty acid profiles (gas chromatography) showed
significant rise in EFAs (linolenic acid and arachidonic acid)
in safflower oil group and saturated fats in coconut oil group
(p <0.05). Changes were more evident in term babies. There
were no side effects associated with the massage. Conclusion:
This study shows that topically applied oil can be absorbed in
neonates and is probably available for nutritional purposes.
The fatty acid constituents of the oil can influence the
changes in the fatty acid profiles of the massaged babies.
Key words: Fatty acid profile, Topical absorption,
Traditional oil .
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk