Ironjustic
Thu, Aug-10-06, 17:15
Investigation of oxidative stress and dietary habits in
Mongolian people, compared to Japanese people Fumio Komatsu1 ,
Yasuo Kagawa* 1 , Mitsuru Sakuma* 1 , Terue Kawabata* 1 ,
Yoshinori Kaneko* 1 , Dugee Otgontuya* 2 , Ulziiburen
Chimedregzen* 2 , Luvsanbazar Narantuya* 2 and Baatar Purvee*
3 1High Technology Research Center, Kagawa Nutrition
University, 3-9-21 Chiyoda, Sakado, Saitama, 350-0288, Japan
2Public Health Institute, Ministry of Health of Mongolia,
Peace Avenue-17, Ulaanbaatar-49, Mongolia 3Khuvsgul General
Hospital, Khuvsgul Aimag, Mongolia
Nutrition & Metabolism 2006, 3:21 doi:10.1186/1743-7075-3-21
Published 7 June 2006
Abstract
Background
The average life span of Mongolians is 62 years for males and
69 years for females. This life span is about 16 years shorter
than that of Japanese. Mongolian people generally eat meat,
fat and diary products but less vegetables or fruit. Thus, we
investigated the state of oxidative stress and dietary habits
of Mongolians.
Methods
The investigation was performed in Murun city in the northwest
area of Mongolia. A total of 164 healthy subjects (24-66 y)
were enrolled. As a marker of reactive oxygen species, the
levels of reactive oxygen metabolites (ROM) were measured
using the d-ROM test. Interviews about dietary habits were
performed using the Food Frequency Questionnaire established
by the Kagawa Nutrition University.
Results
ROM levels were 429.7 =B1 95.2 Carr U for Murun subjects,
whereas Japanese people (n =3D 220, 21-98 y) showed 335.3 =B1
59.8 (p < 0.001). The levels of serum malondialdehyde-modified
low-density lipoprotein-cholesterol and urinary
8-hydroxydeoxyguanosine were also high. ROM levels correlated
with body fat ratio and inversely correlated with handgrip
strength. Handgrip strength in the subjects over 45 years
decreased more rapidly than that of age-matched Japanese.
Murun subjects ate larger amounts of meat, fat, milk and flour
and dairy products than Japanese, but less vegetables or
fruit. Serum vitamin A and E levels were the same as Japanese
references, but vitamin C levels were lower.
Conclusion
Murun subjects may be in high oxidative stress, which may have
a relationship with early ageing and several diseases,
ultimately resulting in their short life span. In order to
increase antioxidant capacity and suppress overproduction of
ROM, antioxidant food intake is recommended.
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING=20 http://tinyurl.com/zk9fk
Mongolian people, compared to Japanese people Fumio Komatsu1 ,
Yasuo Kagawa* 1 , Mitsuru Sakuma* 1 , Terue Kawabata* 1 ,
Yoshinori Kaneko* 1 , Dugee Otgontuya* 2 , Ulziiburen
Chimedregzen* 2 , Luvsanbazar Narantuya* 2 and Baatar Purvee*
3 1High Technology Research Center, Kagawa Nutrition
University, 3-9-21 Chiyoda, Sakado, Saitama, 350-0288, Japan
2Public Health Institute, Ministry of Health of Mongolia,
Peace Avenue-17, Ulaanbaatar-49, Mongolia 3Khuvsgul General
Hospital, Khuvsgul Aimag, Mongolia
Nutrition & Metabolism 2006, 3:21 doi:10.1186/1743-7075-3-21
Published 7 June 2006
Abstract
Background
The average life span of Mongolians is 62 years for males and
69 years for females. This life span is about 16 years shorter
than that of Japanese. Mongolian people generally eat meat,
fat and diary products but less vegetables or fruit. Thus, we
investigated the state of oxidative stress and dietary habits
of Mongolians.
Methods
The investigation was performed in Murun city in the northwest
area of Mongolia. A total of 164 healthy subjects (24-66 y)
were enrolled. As a marker of reactive oxygen species, the
levels of reactive oxygen metabolites (ROM) were measured
using the d-ROM test. Interviews about dietary habits were
performed using the Food Frequency Questionnaire established
by the Kagawa Nutrition University.
Results
ROM levels were 429.7 =B1 95.2 Carr U for Murun subjects,
whereas Japanese people (n =3D 220, 21-98 y) showed 335.3 =B1
59.8 (p < 0.001). The levels of serum malondialdehyde-modified
low-density lipoprotein-cholesterol and urinary
8-hydroxydeoxyguanosine were also high. ROM levels correlated
with body fat ratio and inversely correlated with handgrip
strength. Handgrip strength in the subjects over 45 years
decreased more rapidly than that of age-matched Japanese.
Murun subjects ate larger amounts of meat, fat, milk and flour
and dairy products than Japanese, but less vegetables or
fruit. Serum vitamin A and E levels were the same as Japanese
references, but vitamin C levels were lower.
Conclusion
Murun subjects may be in high oxidative stress, which may have
a relationship with early ageing and several diseases,
ultimately resulting in their short life span. In order to
increase antioxidant capacity and suppress overproduction of
ROM, antioxidant food intake is recommended.
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING=20 http://tinyurl.com/zk9fk