Ironjustic
Wed, Aug-09-06, 06:15
<<snip>> CONCLUSION: RA and SLE patients have HIGH levels of
prooxidants (MDA and NO) whereas their antioxidant enzymes
(SOD and GPO) activity was LOW. <<snip>>
[Pro- and antioxidant blood system in patients with rheumatoid
arthritis and systemic lupus erythematosus] Ter Arkh. 2006;
78(6): 10-4
AIM: To estimate the levels of prooxidants (malonic
dialdehyde-MDA and nitric oxide-NO), Zn, activity of
antioxidant enzymes (superoxide dismutase--SOD and glutathione
peroxidase--GPO) in the blood of patients with rheumatoid
arthritis (RA) and systemic lupus erythematosus (SLE).
MATERIAL AND METHODS: Pro- and antioxidant system was assessed
in 45 RA patients and 32 SLE patients by content of MDA
estimated by reaction with thiobarbituric acid, NO (Boehringer
Manheim kits, Germany), Zn (Unicam SP 190/191, Great Britain),
activity of SOD and GPO (kits Ransod, Ransel; Randox, Great
Britain). RA activity was evaluated by DAS index, SLE--by
SLEDAI. RESULTS: MDA and NO concentrations were found elevated
while SOD and GPO activity low in RA and SLE. The level of Zn
was subnormal in RA. The activity of RA and SLE did not
influence the above indices significantly. CONCLUSION: RA and
SLE patients have high levels of prooxidants (MDA and NO)
whereas their antioxidant enzymes (SOD and GPO) activity was
low. This may promote oxidant stress.
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
prooxidants (MDA and NO) whereas their antioxidant enzymes
(SOD and GPO) activity was LOW. <<snip>>
[Pro- and antioxidant blood system in patients with rheumatoid
arthritis and systemic lupus erythematosus] Ter Arkh. 2006;
78(6): 10-4
AIM: To estimate the levels of prooxidants (malonic
dialdehyde-MDA and nitric oxide-NO), Zn, activity of
antioxidant enzymes (superoxide dismutase--SOD and glutathione
peroxidase--GPO) in the blood of patients with rheumatoid
arthritis (RA) and systemic lupus erythematosus (SLE).
MATERIAL AND METHODS: Pro- and antioxidant system was assessed
in 45 RA patients and 32 SLE patients by content of MDA
estimated by reaction with thiobarbituric acid, NO (Boehringer
Manheim kits, Germany), Zn (Unicam SP 190/191, Great Britain),
activity of SOD and GPO (kits Ransod, Ransel; Randox, Great
Britain). RA activity was evaluated by DAS index, SLE--by
SLEDAI. RESULTS: MDA and NO concentrations were found elevated
while SOD and GPO activity low in RA and SLE. The level of Zn
was subnormal in RA. The activity of RA and SLE did not
influence the above indices significantly. CONCLUSION: RA and
SLE patients have high levels of prooxidants (MDA and NO)
whereas their antioxidant enzymes (SOD and GPO) activity was
low. This may promote oxidant stress.
Who loves ya. Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk