Motor Neurone Disease / Omega-3 and -6 fatty acids and vitamin E

[Ironjustic]

Omega-3, -6 and vitamin E could cut MND risk

By Stephen Daniells

27/04/2006 - Omega-3 and -6 fatty acids and vitamin E in the
diet could slash the risk of motor neurone disease (MND)
by 60 per cent, say new research from the Netherlands.

According to the Motor Neurone Disease Association, the
disease affects about seven people in every 100,000, with life
expectancy of only two to five years. The disease
characterized by the gradual death of motor neurones in the
brain, which then stops muscles from working. The cause is
unknown and there is no cure. The new study, published on-line
in the Journal of Neurology (doi:
27.05/jnnp.2005.083378), reports that a diet rich in
polyunsaturated fatty acids (omega-3 and omega-6)
and vitamin E could reduce the risk of developing
the disease.

The researchers, from the University Medical Centre, Utrecht,
investigated the diets of 132 people with a form of MND called
amytrophic lateral sclerosis (ALS). Their dietary habits were
compared to 220 control subjects who did not have the disease.
Dietary habits were evaluated using a validated 104-item food
frequency questionnaire.

While energy intake and supplement intake was similar between
the groups, the researchers found that intake of vitamin E and
polyunsaturated fatty acids (PUFAs) was noticeably lower in
the ALS cases, which agreed with the original hypothesis.

People whose intake was more than 32 grams of PUFAs per day
had a 60 per cent lower risk of ALS than those who consumed
less than 25 grams per day. No differentiation between omega-3
and omega-6 was performed by the researchers.

A daily intake of vitamin E over 18 milligrams was associated
with a 60 per cent reduction in the risk of ALS.

No relationship between flavonol, lycopene, or vitamins B2 and
C were observed by the researchers.

"This study shows that higher premorbid dietary intake of
PUFAs and vitamin E was associated with a 50 to 60 per
cent decreased risk of developing ALS," wrote lead author
Jan Veldink.

The mechanism, say the researchers, is more than just the
nutrients' individual benefits. The omega-3 fatty acid,
alpha-linoleic acid, for example, has been reported to protect
neurones. Docosahexaenioc acid (DHA) is involved in the
membrane of ion channels in the brain, making it easier for
them to change shape and transit electrical signals. Vitamin
E, say the scientists, inhibits lipid peroxidation which leads
to oxidative stress.

The nutrients' protective activity, says Veldink, is a case of
the sum greater than the parts.

"The combined analysis, including the interaction term,
indicates that vitamin E and PUFAs increase their separate
protective effects. Vitamin E may act directly to reduce the
risk of ALS as a known inhibitor of lipid peroxidation, but
it could also act indirectly through inhibition of
peroxidation of PUFAs.

As a result, a higher level of PUFAs will be available
biologically," said Veldink.

Although further research is clearly needed, the results do
fit with reports on the benefits of this nutrient combo for
cognitive diseases. According to other studies, the risk of
Alzheimer's disease could be reduced by a diet risk in plant
lipids, fish, or by eating a Mediterranean-style diet, rich in
both PUFAs and vitamin E.

The study has several limitations, including being
non-population based and depending on dietary recall of both
the cases and controls. Veldink and his colleagues are
currently conducting a population-based case-control study to
further test their hypothesis.

Famous people with MND include the actor David Niven and
Professor Stephen Hawking.

Who loves ya. Tom

Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com

Man Is A Herbivore! http://tinyurl.com/a3cc3

DEAD PEOPLE WALKING http://tinyurl.com/zk9fk

[monty1945]

To say this study has numerous limitations is actually an
understatement. The actual molecular-level mechanisms are
known, and so this kind of correlations thing can only be
misleading. Stress causes release of the omega 6, AA, and the
AA metabolites do the damage
- that is now totally understood, Most Westerners do not have
much omega 3 in them, but there are dangerous metabolites
(non-enzymatic especially) of omega 3s. The studies mostly
measure the omega 6 metabolites, so omega 3 is said to be
healthy. The old experiments, which fed animals different
diets, such as one high in fish oil, and then observed the
health and longevity of the animals, uniformly resulted in
animals dying young when given high omega 6/3 diets. Now if
you load them up with vitamin E, then yes, there will be a
counteracting effect, but nobody knows if this is a good
idea in humans, and recent studies sugggest that it is not,
due to the unbalancing of the different molecules classified
as "vitamin E." Get your own mice, load one group up with
fish oil and/or canola oil, and load the other group up with
fresh coconut oil, without any extra vitamin E and you will
see what the scientfic reality is. No need for these kinds
of ludicrious "studies," some of which appear to be
intentionally misleading.

[Mr. Natura]

ironjustice@aol.com wrote:

> Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com

This statement of yours is still nutty. And, is totally
without foundation. What is your problem?

See: _What Would Jesus Eat? : The Ultimate Program for Eating
Well, Feeling Great, and Living Longer_ by Don Colbert, MD
ISBN: 0785273190 http://www.amazon.com/gp/product/0785273190/-
qid=1152009660/sr=1-2/ref=sr_1_2/103-9791175-5296603?s=books&-
v=glance&n=283155 "From Publishers Weekly ... Author Don
Colbert, a family physician, urges readers to examine and
emulate Jesus' simple diet. The nutritional information,
overall, is quite sound: Colbert encourages the consumption of
fish, the use of olive oil in cooking and an exercise regimen
of daily walking. He discusses the "hidden dangers" of pork,
condemns refined white flour and warns against the excessive
consumption of red meat."

The Seventh-Day Adventists points towards the Book of Genesis
and Ellen White for their vegetarian diet. They certainly do
NOT talk about Jesus.

"Reviewer: M. Markstein - See all my reviews Despite what T.
Smith (another reviewer) states, Jesus was under no vegetarian
obligation. God has made multiple covenants with his
followers, and in each covenant the previous one was replaced.
Thus post-Noah followers could eat meat, and post-Jesus
followers had no obligation to be kosher. Which brings me to
my main point: why should one feel any significance in eating
what Jesus ate?"

Just thought that you might want to know.

[Sylv]

Mr. Natural-Health wrote:
> ironjustice@aol.com wrote:
>
> > Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
>
> This statement of yours is still nutty. And, is totally
> without foundation. What is your problem?

He's just totally crazy, not to mention dumb as a box of
rocks.

No use trying to argue with him; reason and logic are out of
his reach.

Sylvia

[Mr. Natura]

Michael wrote:
> "Mr. Natural-Health"
> <johngohde@naturalhealthperspective.com> wrote in message
> news:1152063878.209286.295240@j8g2000cwa.googlegroups.com...
> > Sylv wrote:
> >> Mr. Natural-Health wrote:
> >> > ironjustice@aol.com wrote:
> >> >
> >> > > Jesus Was A Vegetarian!
> >> > > http://jesuswasavegetarian.7h.com
> >> >
> >> > This statement of yours is still nutty. And, is totally
> >> > without foundation. What is your problem?
> >>
> >> He's just totally crazy, not to mention dumb as a box of
> >> rocks.
> >>
> >> No use trying to argue with him; reason and logic are out
> >> of his reach.
> >
> > We now have it in book form. And, ironjustice is NOT only
> > dumb, but he is WRONG. :)
>
>
> But with neither reason nor logic to guide him, how would
> *he* know that?
> :-)

Beats me!!! Perhaps, he might walk into a metal post and fall
down? Maybe, he might eventually get around to reading this
thread that he started? Nah!!!

Interestingly enough, John Harvey Kellogg is on the record for
being against the consumption of fish. http://naturalhealthpe-
rspective.com/tutorials/john-kellogg.html

I on the other hand advocate eating cold water fatty fish. :)
--
John Gohde, Achieving good Nutrition is an Art, NOT a Science!

The nutrition of eating a healthy diet is a biological factor
of the mind-body connection. Now, weighing in at 18 web pages,
the Nutrition of a Healthy Diet is with more documentation and
sharper terminology than ever before.
http://naturalhealthperspective.com/food/

[Mattlb]

monty1945@lycos.com wrote:
> To say this study has numerous limitations

It says "several" limitations, but when have you ever let a
chance to exaggerate go by?

> is actually an understatement. The actual molecular-level
> mechanisms are known, and so this kind of correlations thing
> can only be misleading. Stress causes release of the omega
> 6, AA, and the AA metabolites do the damage
> - that is now totally understood, Most Westerners do not
> have much omega 3 in them, but there are dangerous
> metabolites (non-enzymatic especially)

What are you referring to? How are they metabolites if enzymes
aren't involved?

> of omega 3s. The studies mostly measure the omega 6
> metabolites, so omega 3 is said to be healthy.

What about that ones that specifically measure omega 3 and
declare it healthy?

> The old experiments, which fed animals different diets,
> such as one high in fish oil, and then observed the health
> and longevity of the animals, uniformly resulted in animals
> dying young when given high omega 6/3 diets.

Dying of what?

> if you load them up with vitamin E, then yes, there will be
> a counteracting effect, but nobody knows if this is a good
> idea in humans,

You mean if the bad effects of PUFA don't happen in the
presence of Vitamin E, your theories are up the spout.

> and recent studies sugggest that it is not, due to the
> unbalancing of the different molecules classified as
> "vitamin E."

So you take a mixed tocopherol supplement. Easy.

> your own mice, load one group up with fish oil and/or canola
> oil, and load the other group up with fresh coconut oil,

Let's make the fish and canola oil fresh too, to be fair.

> without any extra vitamin E and you will see what the
> scientfic reality is.

The scientific reality is that vitamin E is the predominant
lipophilic antioxidant and to deliberately exclude it from the
diet is asking for trouble.

> No need for these kinds of ludicrious "studies," some of
> which appear to be intentionally misleading.

A bit like your interpretations of studies.

MattLB

[Alan Meyer]

<monty1945@lycos.com> wrote in message
news:1151992915.032631.67100@75g2000cwc.googlegroups.com...
> To say this study has numerous limitations is actually an
> understatement.
...

There is an often quoted study in the Journal of Neuroscience
(http://www.jneurosci.org/cgi/content/full/25/12/3032) that
fed two diets to older mice, one heavy in an omega 3 fatty
acid and one without that component. The mice with the omega
3 had greatly reduced beta amyloid protein and amyloid
precursor proteins.

Are you arguing that this result too is misleading and that
the dangers of omega 3 are greater than the benefits?

Can you give us a citation?

Thanks.

Alan

[Michael]

"Mr. Natural-Health" <johngohde@naturalhealthperspective.com>
wrote in message
news:1152063878.209286.295240@j8g2000cwa.googlegroups.com...
> Sylv wrote:
>> Mr. Natural-Health wrote:
>> > ironjustice@aol.com wrote:
>> >
>> > > Jesus Was A Vegetarian!
>> > > http://jesuswasavegetarian.7h.com
>> >
>> > This statement of yours is still nutty. And, is totally
>> > without foundation. What is your problem?
>>
>> He's just totally crazy, not to mention dumb as a box
>> of rocks.
>>
>> No use trying to argue with him; reason and logic are out
>> of his reach.
>
> We now have it in book form. And, ironjustice is NOT only
> dumb, but he is WRONG. :)

But with neither reason nor logic to guide him, how would *he*
know that?
:-)

[Michael]

Speaking of which...

A friend gave me a couple of beautiful chunks of chinook
salmon fillet today, and they practically *screamed* "sushi
rolls" at me... so I went to work on making me some for
supper. :-)

They were simple: cold flavoured rice, chives from the
porch-planter, thin slivers of radish and shallot, and lots of
fish. They also gave me a major 10 minute case of wasabi-nose
because I couldn't bring myself to stop once I got into eating
them. The beer - a friend's and my homebrewed blonde pilsener
- isn't really quite ready (needs two more days at *least*),
but it's settled out all its yeast, and being very slightly
sweet and not yet fully carbonated made it a pretty good match
for the food - and for the *quantity* of food.

The photos? The translucency of that hunk of fish is
beautifully captured, but I really like the top view of the
finished product best... and it's neat to see the hollow
arrays of chives in cross-section like that.

There's just about 1/3 of all ingredients left, wrapped up
neatly in the fridge for breakfast... but I'd happily have
eaten lighter and shared the whole shebang. All anyone
really needs first thing in the morning anyhow (when and if
dragging one's ass out of bed ever becomes an issue) is
enough coffee. :-)

http://qcislands.ca/muirhead/GonnaBeSushi(2).jpg
http://qcislands.ca/muirhead/NotSuhsiYetJustFixins(2).jpg
http://qcislands.ca/muirhead/OK_NowItsSushi(2).jpg http://qci-
slands.ca/muirhead/SushiButNotAsahi_BonAppétit(2).jpg
http://qcislands.ca/muirhead/PleaseSirIWantMore(2).jpg

[Michael]

> http://qcislands.ca/muirhead/NotSuhsiYetJustFixins(2).jpg

Oooops...

http://qcislands.ca/muirhead/NotSushiYetJustFixins(2).jpg

[Alex]

Michael wrote:
> Speaking of which...
>
> A friend gave me a couple of beautiful chunks of chinook
> salmon fillet today, and they practically *screamed* "sushi
> rolls" at me... so I went to work on making me some for
> supper. :-)
>
> They were simple: cold flavoured rice, chives from the
> porch-planter, thin slivers of radish and shallot, and lots
> of fish. They also gave me a major 10 minute case of
> wasabi-nose because I couldn't bring myself to stop once I
> got into eating them. The beer - a friend's and my
> homebrewed blonde pilsener - isn't really quite ready (needs
> two more days at *least*), but it's settled out all its
> yeast, and being very slightly sweet and not yet fully
> carbonated made it a pretty good match for the food - and
> for the *quantity* of food.
>
> The photos? The translucency of that hunk of fish is
> beautifully captured, but I really like the top view of the
> finished product best... and it's neat to see the hollow
> arrays of chives in cross-section like that.
>
> There's just about 1/3 of all ingredients left, wrapped up
> neatly in the fridge for breakfast... but I'd happily have
> eaten lighter and shared the whole shebang. All anyone
> really needs first thing in the morning anyhow (when and if
> dragging one's ass out of bed ever becomes an issue) is
> enough coffee. :-)
>
> http://qcislands.ca/muirhead/GonnaBeSushi(2).jpg
> http://qcislands.ca/muirhead/NotSuhsiYetJustFixins(2).jpg
> http://qcislands.ca/muirhead/OK_NowItsSushi(2).jpg http://q-
> cislands.ca/muirhead/SushiButNotAsahi_BonAppétit(2).jpg
> http://qcislands.ca/muirhead/PleaseSirIWantMore(2).jpg
>
>

Nice! <wipes drool off of chin>

A suggestion for you, however.

Your links above, as viewed in the Thunderbird mail & news
reader, appear as follows:

The text in the message appears as:
http://qcislands.ca/muirhead/GonnaBeSushi(2).jpg but the
hyperlink itself appears as:
http://qcislands.ca/muirhead/GonnaBeSushi(2

Thunderbird treats the ) as a closing delimiter, so ends the
hyperlink at that point. To work around that you can enclose
the link in <> as
in: <http://qcislands.ca/muirhead/GonnaBeSushi(2).jpg>

or you can just avoid the use of () in the links.

I don't know how other readers treat the links, but thought I
would make the suggestion.

Have a good breakfast!

Alex

[Michael]

Mr. Natural-Health wrote:

> Michael wrote:
>> "Mr. Natural-Health"
>> <johngohde@naturalhealthperspective.com> wrote in
>> message news:1152063878.209286.295240@j8g2000cwa.google-
>> groups.com...
>>> Sylv wrote:
>>>> Mr. Natural-Health wrote:
>>>>> ironjustice@aol.com wrote:
>>>>>
>>>>>> Jesus Was A Vegetarian!
>>>>>> http://jesuswasavegetarian.7h.com
>>>>>
>>>>> This statement of yours is still nutty. And, is totally
>>>>> without foundation. What is your problem?
>>>>
>>>> He's just totally crazy, not to mention dumb as a box of
>>>> rocks.
>>>>
>>>> No use trying to argue with him; reason and logic are out
>>>> of his reach.
>>>
>>> We now have it in book form. And, ironjustice is NOT only
>>> dumb, but he is WRONG. :)
>>
>>
>> But with neither reason nor logic to guide him, how would
>> *he* know that? :-)
>
> Beats me!!! Perhaps, he might walk into a metal post and
> fall down?

I doubt he's unfamiliar with the experience.

> Maybe, he might eventually get around to reading this thread
> that he started? Nah!!!

He'll come back to swear at it if he comes back at all... but
he'll read it. He's only as known as the responses to his
posts indicate, after all.

> Interestingly enough, John Harvey Kellogg is on the record
> for being against the consumption of fish. http://naturalhe-
> althperspective.com/tutorials/john-kellogg.html
>
> I on the other hand advocate eating cold water fatty
> fish. :)

Avoid tuna, if you'r going to avoid fish at all. I don't, (I
have several kilos of albacore steaks in the freezer) but it's
among the most mercury-and-PCB-laden, top-of-the-foodchain
animals on the planet.

[Michael]

"Michael" <muirhead@haidagwaii.net> wrote in message
news:L7ydnT7yoPClzTbZnZ2dnUVZ_oydnZ2d@qcislands.net...
>> http://qcislands.ca/muirhead/NotSuhsiYetJustFixins(2).jpg
>
> Oooops...
>
> http://qcislands.ca/muirhead/NotSushiYetJustFixins(2).jpg

... errr... and,

> http://qcislands.ca/muirhead/SushiButNotAsahi_BonAppéti-
> t(2).jpg

I can't type, and friggin browsers don't believe in accented
chars...<grrrr>

http://qcislands.ca/muirhead/SushiButNotAsahi_BonAppetit(2).j-
pg

[Dci]

On Tue, 4 Jul 2006 22:37:58 -0700, "Michael"
<muirhead@haidagwaii.net> wrote:

>> http://qcislands.ca/muirhead/NotSuhsiYetJustFixins(2).jpg
>
>Oooops...
>
>http://qcislands.ca/muirhead/NotSushiYetJustFixins(2).jpg
>
>

Nothing shows up.

Donn

[Dci]

On Tue, 4 Jul 2006 22:45:28 -0700, "Michael"
<muirhead@haidagwaii.net> wrote:

>
>"Michael" <muirhead@haidagwaii.net> wrote in message
>news:L7ydnT7yoPClzTbZnZ2dnUVZ_oydnZ2d@qcislands.net...
>>> http://qcislands.ca/muirhead/NotSuhsiYetJustFixins(2).jpg
>>
>> Oooops...
>>
>> http://qcislands.ca/muirhead/NotSushiYetJustFixins(2).jpg
>
>... errr... and,
>
>> http://qcislands.ca/muirhead/SushiButNotAsahi_BonAppétit-
>> (2).jpg
>
>I can't type, and friggin browsers don't believe in accented
>chars...<grrrr>
>
>http://qcislands.ca/muirhead/SushiButNotAsahi_BonAppet-
>it(2).jpg
>

Nothing shows up here, either.

Donn

[Michael]

DCI wrote:

> On Tue, 4 Jul 2006 22:45:28 -0700, "Michael"
> <muirhead@haidagwaii.net> wrote:
>
>>
>> "Michael" <muirhead@haidagwaii.net> wrote in message
>> news:L7ydnT7yoPClzTbZnZ2dnUVZ_oydnZ2d@qcislands.net...
>>>> http://qcislands.ca/muirhead/NotSuhsiYetJustFixins(2).jpg
>>>
>>> Oooops...
>>>
>>> http://qcislands.ca/muirhead/NotSushiYetJustFixins(2).jpg
>>
>> ... errr... and,
>>
>>> http://qcislands.ca/muirhead/SushiButNotAsahi_BonAppétit(-
>>> 2).jpg
>>
>> I can't type, and friggin browsers don't believe in
>> accented chars...<grrrr>
>>
>> http://qcislands.ca/muirhead/SushiButNotAsahi_BonAppetit-
>> (2).jpg
>>

Give both a few minutes... I had to edit stuff, and my local
server has to synch with the remote one in Vancouver before
the world can see the result.
:-)

[Mr. Natura]

Sylv wrote:
> Mr. Natural-Health wrote:
> > ironjustice@aol.com wrote:
> >
> > > Jesus Was A Vegetarian!
> > > http://jesuswasavegetarian.7h.com
> >
> > This statement of yours is still nutty. And, is totally
> > without foundation. What is your problem?
>
> He's just totally crazy, not to mention dumb as a box
> of rocks.
>
> No use trying to argue with him; reason and logic are out of
> his reach.

We now have it in book form. And, ironjustice is NOT only
dumb, but he is WRONG. :)