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kebaldwin
Sat, Dec-31-05, 11:42
Who Really is Writing All Those Scientific Studies?

It's an open secret in medicine that many of the articles that appear in medical journals, often purporting to be written by well-known academics, are actually written by unacknowledged ghostwriters in the pay of drug companies.

These "seemingly objective articles" are usually actually part of a marketing campaign to promote a product or draw attention to the condition it treats.

The Role of Medical Journals

However, questions about the role of medical journals have increased in the wake of the New England Journal of Medicine's admission that a 2000 article it published about Vioxx painkiller omitted information about heart attacks among those taking the drug. One element that is being looked at sharply is the "ghostwriting" practice and the medical journals' rules of author disclosure.

Biased Information

Increasingly, the practice of medical ghostwriting is being criticized on the grounds that it could hurt patients by giving doctors biased information. Drug companies claim that they're providing a service to academic researchers, who may not be skilled writers, and do not intend that the articles be biased.

An Unknown Number of Articles

An analysis found that 10 percent of articles on studies sponsored by the drug industry disclosed help from a medical writer. However, often the practice is not disclosed. An informal poll found that 80 percent of freelance medical writers had written articles that did not mention their contributions.

Pittsburgh Post-Gazette December 13, 2005

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Dr. Mercola's Comment:

This is not a new issue as I wrote about this last year, however this is one of the primary ways the drug companies are able to manipulate and brainwash conventional medicine practitioners.

They influence the very heart and center of the most respected medical journals and are able to create dogmas and beliefs that support the drug paradigm because it is blessed by paragon of scientific integrity, the peer-reviewed prestigious medical journal.

No matter what the industry claims, undisclosed authors paid by the multi-national drug companies have no chance of remaining unbiased. Why bother to conceal their identities otherwise?

Hopefully, the news about the erroneous and biased Vioxx study that Merck foisted off on the New England Journal of Medicine will lead journals and scientists to take a good hard look at the practices of conventional medicine. Not surprisingly, another journal -- Annals of Internal Medicine -- found itself in similar hot water earlier this year when one of the "authors" of a 2003 Vioxx study it published confessed he had little to do with the research.

Drug companies claim they're providing a "service" to lesser writers by providing ghostwriters. What they're actually doing is trying to spin the data and brainwash physicians to be puppets for their agenda.

A 1999 document that was disclosed in a lawsuit described Pfizer's publications strategy for its antidepressant Zoloft. The document included 81 different articles proposed for journals, promoting the drug's use for problems ranging from panic disorder to pedophilia.

The only problem was, for some articles, the name of the author was listed as "to be determined," even though the article was listed as already completed. They weren't helping out an existing team of scientists who happened to be talentless at writing -- Pfizer wrote the article, then shopped around for scientists to put their name on it to give it a veneer of credibility.

More evidence, folks, it always pays to be skeptical and observant when it comes to your health, especially with all the money drug companies throw at researchers as well as you in the form of advertising. When it comes to drugs like Vioxx, your life could genuinely be at stake.

That is one of the reasons why I publish this newsletter. To give you another view to consider as an alternative to the one being fostered on you by tens of billions of dollars of marketing influence.

Related Articles:

Medical Journal Drug Ads Often Misleading

$30 Billion Vioxx Recall -- The Dangers, Powerful Lessons & Safe Alternatives that Everyone Must Know

Finally Medical Journal Admits the Truth About Bird Flu

http://www.mercola.com/2005/dec/31/who_really_is_writing_all_those_scientific_studies.htm

Zuleikaa
Sat, Dec-31-05, 14:23
I knew that years ago.

But it's good it's being brought back up. Maybe people will become more skeptical.

kebaldwin
Sun, Jan-01-06, 08:00
There are several categories of articles from the pharma companies

1. Touting the currently approved use of their products -- trying to make it sound like news. Sometimes they tout drugs they are developing to try to increase their stock price / business outlook.

2. Expanding the scope / use of their products. For example, with gastric bypass -- they now are talking about how great it will be for teens and senior citizens. Or some drugs approved for arthritis -- the pharma companies want it approved for Parkinsons, and a bunch of other diseases.

3. FUD Fear, Uncertainty, and Doubt. This is when marketing groups go on the offensive and attack competing solutions. The aspirin / Tylenol / Ibuprofen companies have been doing this a lot lately. Plus they attack natural remedies as FUD - don't work, waste of money, and could even be down right dangerous !

IMHO, there are a lot of great things that medical and pharma companies do. But lately there are more and more not so great things that they do.

Instead of just a drug tested against a placebo -- IMHO, their drugs should be tested with a control group made up of people on a low carb diet (I prefer Atkins with supplements), non smoking, non / moderate drinking.

They should also test against the best of natural supplements.

If a drug passed these tests -- then it would be well worth prescribing.

Scars
Sun, Jan-01-06, 14:46
Very interesting... I have my issues with Mercola, however (won't get into that now). Fact is, there are plenty of studies that validate reduced carb, higher protein higher fat ways of eating. You just have to know how to interpret and evaluate studies and their associated applications. It is also important to how the design of the study and how it was funded. Far too often people disregard all studies as "biased" and use this red-herring to absolve themselves of proving their own unsubstantiated theories (such as Dr. Mercola). The vegan Taliban (PETA/PCRM) uses such a strategy, as do many alternative health practitioners. I am not anti-CAM, but there are very sketchy players in the alternative health world. Bashing alopathic medicine is their way of promoting their own concepts/products/cults...

Just another side of things to ponder...

Hybrid
Sun, Jan-01-06, 15:05
For a good look at the issues involved beyond health and diet: http://www.alternativescience.com/index.htm

ceberezin
Sun, Jan-01-06, 17:06
The problem is not just that articles in peer-reviewed journals hype one pharma company's drugs over another. It's that they all push the disease management dogma, in which conditions are defined as diseases to be treated as separate entities by particular drugs. We, on this board and other such places have been finding out that this dogma is wrong, that 80% of the conditions for which people take prescription drugs could be lessened or eliminated by controlling insulin and insulin resistance.

My problem with the alternative health people is that they accept and reinforce the disease management dogma. They just claim that their natural products are better than the pharamaceutical companys' designer molecules. They're both wrong.

Scars
Sun, Jan-01-06, 21:54
The problem is not just that articles in peer-reviewed journals hype one pharma company's drugs over another. It's that they all push the disease management dogma, in which conditions are defined as diseases to be treated as separate entities by particular drugs. We, on this board and other such places have been finding out that this dogma is wrong, that 80% of the conditions for which people take prescription drugs could be lessened or eliminated by controlling insulin and insulin resistance.

My problem with the alternative health people is that they accept and reinforce the disease management dogma. They just claim that their natural products are better than the pharamaceutical companys' designer molecules. They're both wrong.

Well said...couldn't agree more.

SidC
Sun, Jan-01-06, 23:05
One other problem with peer-reviewed articles, pointed out by my ex, the physical chemist, is a problem that transcends politics and $. Call it the academic dogma problem.

Once a "result" has been published and accepted by the scientific community, papers that find different results are generally rejected. It takes years, sometimes decades, of people producing different results (failing to replicate), before a new data point is published. So what you see in the literature is a string of .2, .25, .23, .18....then a breakthrough article with 2.5, followed by studies that report 2.4, 2.34, etc.

Why? Because 1) academics and researchers are also pressed for time and reviewing journal articles doesn't count for much in terms of prestige or promotion and 2) you have to be very sure of yourself to OK a study that goes against the standard.

So yes, be skeptical of the trials financed by the drug companies, as well as the cultural mind-set that focusses on disease management. But also be aware that there is this other bias in peer-reviewed papers that has nothing to do with where the funding comes from or the preconceptions of the authors. Bottom line - trust little except your own experience.

Galliard
Mon, Jan-02-06, 13:48
The Truth About the Drug Companies by Marcia Angell, a former editor in chief for the New England Journal of Medicine was an eye-opener for me. It thoroughly debunks the scientific validity of most new drug studies (along with much else about the drug companies). My favorite: FDA-approved tests of new drugs don't have to prove they're better than anything except a placebo. Newer, more expensive drugs never, ever go up against time-tested, less expensive treatments that have been proven over many years not to have excessively dangerous side effects. Basically new drugs just have to prove they're better than nothing!