Ironjustic
Wed, Jul-06-05, 06:30
1: Osteoporos Int. 2005 Jul 5; [Epub ahead of print] Links
Osteoporosis in HFE2 juvenile hemochromatosis. A case report
and review of the literature.
Angelopoulos NG, Goula AK, Papanikolaou G, Tolis G.
Division of Endocrinology and Metabolism, "Hippokrateion"
Hospital of Athens, Vassilisis Sofias Avenue 108, 115 27,
Athens, Greece, drangelnick@hotmail.com.
Juvenile hemochromatosis (JH) is a severe form of
hemochromatosis, which involves rapid iron overload and leads
to organ damage, typically before the age of 30. We report a
single case of a 25-year-old man suffering from juvenile
hemochromatosis, with aggressive clinical manifestations,
typically characterized by transaminasemia and progressive
erectile dysfunction, due to hypogonadotropic hypogonadism.
The clinical case appears interesting, as the patient also
had secondary osteoporosis accompanied by increased bone
resorption, which prevalently affected trabecular bone.
Approximately 6 months after normalization of serum ferritin
levels was achieved by frequent phlebotomies, he became
eugonadal and bone mineral density of the lumbar spine
increased. Our observations suggest that osteoporosis might
occur in the state of JH even at a young age, mainly due to
the deprivation of sex steroids and the direct tissue
toxicity of iron.
PMID: 15997423 [PubMed - as supplied by publisher]
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http://jesuswasavegetarian.7h.com Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore DEAD
PEOPLE WALKING
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Osteoporosis in HFE2 juvenile hemochromatosis. A case report
and review of the literature.
Angelopoulos NG, Goula AK, Papanikolaou G, Tolis G.
Division of Endocrinology and Metabolism, "Hippokrateion"
Hospital of Athens, Vassilisis Sofias Avenue 108, 115 27,
Athens, Greece, drangelnick@hotmail.com.
Juvenile hemochromatosis (JH) is a severe form of
hemochromatosis, which involves rapid iron overload and leads
to organ damage, typically before the age of 30. We report a
single case of a 25-year-old man suffering from juvenile
hemochromatosis, with aggressive clinical manifestations,
typically characterized by transaminasemia and progressive
erectile dysfunction, due to hypogonadotropic hypogonadism.
The clinical case appears interesting, as the patient also
had secondary osteoporosis accompanied by increased bone
resorption, which prevalently affected trabecular bone.
Approximately 6 months after normalization of serum ferritin
levels was achieved by frequent phlebotomies, he became
eugonadal and bone mineral density of the lumbar spine
increased. Our observations suggest that osteoporosis might
occur in the state of JH even at a young age, mainly due to
the deprivation of sex steroids and the direct tissue
toxicity of iron.
PMID: 15997423 [PubMed - as supplied by publisher]
--------------------------------------------------------------
-------------------
Who loves ya. Tom Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore DEAD
PEOPLE WALKING
http://pages.ivillage.com/ironjustice/deadpeoplewalking