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Dodger
Sun, Feb-06-05, 09:47
Study: High-Fat Diets Less Effective at Keeping Hunger at Bay

By Jennifer Warner (http://my.webmd.com/content/Biography/7/1756_54621.htm)
WebMD Medical News
Reviewed By Brunilda Nazario, MD (http://my.webmd.com/content/Biography/7/40428.htm)
Feb. 3, 2005

Want to fight those hunger pangs? A new study shows it may be best to forgo the fat and bring on the carbs and protein.

Researchers found a diet rich in either carbohydrates like grains or protein, such as meats and fish, suppressed the so-called hunger hormone, ghrelin, more effectively than a diet high in fat.

Ghrelin is a recently discovered hormone that is secreted by the stomach and small intestine that is thought to trigger hunger and send a message to the brain to bring on the food. Circulating levels of ghrelin in the body rise just before meals and fall after eating, suggesting that the hormone plays a role in mealtime hunger and initiating food intake.

Controlling the Hunger Hormone

In this study, published in the February issue of Endocrinology, researchers tested the effects of carbohydrates, protein, and fat on ghrelin levels in mice.

The mice were given an infusion of each of the three substances in their small intestines, and then researchers measured grehlin levels at regular intervals up to five hours later.

The study showed that the protein and carbohydrate infusions suppressed ghrelin faster and more effectively than the fat infusion. In particular, the protein and carbohydrates reduced ghrelin levels by 70% compared with the 50% reduction found with fat.

Researchers say these results suggest that high-fat diets may be more likely to promote weight gain because they do not keep hunger at bay as effectively as diets rich in carbohydrates or proteins.

SOURCE: Overduin, J. Endocrinology, February 2005; vol 146: pp 845-850.
http://my.webmd.com/content/Article/100/105662.htm

eepobee
Sun, Feb-06-05, 11:16
should i bother to point out that MICE ARE HERBIVORES!!!!!

ceberezin
Sun, Feb-06-05, 15:10
Hormones do not work alone. Everything that happens in your body has a hormonal pathway in which hormones, enzymes, proteins, etc., do their jobs. To isolate one hormone and say it is the cause of anything is bad science.

VALEWIS
Sun, Feb-06-05, 15:53
Apart from mice being herbivores and comparing their physiology to ours, what about insulin? Does it not play a role in all this? Our collective experiences here would suggest that we all feel hungry not long after a carb meal (depending on the carbs in question and their effect on insulin etc), fat for some of us is satiating and for others is not (look at the fat fast threads...some people are starving, others sated on it), and protein is very filling for just about everyone.

I think the fat question thus is very individual...some people at the same weight lose more weight when they add more fat, others gain. Trying to find one rule that fits all is absurd. But that is true of most things, eh. I think LC has to be tweaked to suit your own body without losing the basic principles.

Val

Duparc
Mon, Feb-07-05, 03:36
A classic example of the differences between theory and practice and of mice and men! Did the mice tell the researchers that they were feeling hungry, or were the 'boffins' once again only guessing?

kimberlyw
Mon, Feb-07-05, 04:40
From my own personal experience, based on my OWN body (Best litmus test for what is best for me I think) this is absoulutely false:
forgo the fat and bring on the carbs and protein
I *KNOW* as in have personally witnessed, that if I eat carby stuff (potatoes, bread, rice, noodles) I am eat more at the time that I eat and I am hungrier again sooner after I eat.

Let me state for the record, that my personal issue is not over-eating or carb addiction or whatever. My issue was meds I was on which caused rapid weight gain.

However: In searching for a way to drop the weight after treatment, I found low-carb. It works for me.

Since that time, I have paid more attention to what I eat and how much and I noticed right away, that I can eat a LOT of noodles or mashed potatoes at a sitting. Not true with fatty foods. I also noticed that when I had say, whole grain brotchen (roll) with cheese on it, I am hungry much sooner than iff I had instead had a few slices of cheese and maybe some tomato slices.

So, for me? Carbs cause hunger pangs, fats stave them off.

:)
~Kimberly

kimberlyw
Mon, Feb-07-05, 04:40
(Speaking of Fats, my eggs are done - off to make deviled eggs!)

SadLady
Mon, Feb-07-05, 05:40
I am like KimberlyW. Proven that if I eat carbs and protein I am going to eat more and be hungry sooner. Can't believe people that do not try the diet and rely only on mice, geeeee !!!!

actionjack
Mon, Feb-07-05, 08:44
should i bother to point out that MICE ARE HERBIVORES!!!!!
Maybe its those darn flesh eating mice! :lol:

Angeline
Mon, Feb-07-05, 08:54
Actually I find that the best combo for long term appetite suppression is fat, protein and carbs. Carbs and protein with no fat will make me not only ravenous but downright hypoglycemic a few hours laters. A good example is sushi. Fat and protein are much better (for example eggs and ham. Carbs and fat also works, but not as well. However Fat, protein and carbs will keep me satisfied the longest.

This is in direct opposition to the article. Absence of fat will systematically make me hungrier faster.

bvtaylor
Mon, Feb-07-05, 09:41
Last time I read about the field mice in my garage, I recall reading that they will eat many different things--certainly grain is a major part of a field mouse's diet, but they love such things as thrown out bacon or chocolate, and love high fat.

Biologically this would make sense for a mouse... probably grainy things are easier to come by for them in the wild during the warmer seasons, and an opportunity to eat leavings of a predator, for example (as I don't think they are as likely to kill things), or scavenging from a human domicile, or typical high fat nut leavings, I would think should be an indicator to trigger fat storage for the less plentiful times during winter and encourage them to eat more rather than less.

In addition, there is a difference in "injecting" food into the intestine rather than getting it through the mouth, I would think. The triggers for appetite can be smells and flavors and I suspect those could also affect the grehlin.


These are interesting links:

http://www.pestmess.com/rodents.html

Food Habits: House mice eat many types of food but prefer seeds and grain. They are not hesitant to sample new foods and are considered "nibblers," sampling many kinds of items that may exist in their environment. Foods high in fat, protein, or sugar may be preferred even when grain and seed also are present. Such items include bacon, chocolate candies, butter and nutmeats. A single mouse eats only about 3 grams of food per day (8 pounds per year) but because of their habit of nibbling on many foods and discarding partially eaten items, mice destroy considerably more food than they consume. Unlike Norway and roof rats, they can get by with little or no free water, although they readily drink water when it is available. They obtain their water needs from the food they eat. An absence of liquid water or food of adequate moisture content in their environment may reduce their breeding potential.

http://unexco.com/mice.html

Sometimes you'll find some kind of foodstuff broken into. They especially seem to like chocolate - even more than cheese!

Mice can live in a freezer, below freezing all of their lives, feeding on nothing but frozen foods. Naturally, we don't mean YOUR freezer, the one you might have at home, but in large, commercial operations, this happens quite often.

Remember, there are a lot of things mice like to eat, so don't store any foodstuffs in your garage. Including grass seed. Mice love grass seed. Or birdseed or pet foods. They like leather, any kind, and furs too. They even like soap! Although they are kind of picky about their soap. They only like real soap - like in Ivory. They won't touch a detergent bar, but they love Ivory! Ivory soap, of course, is some 99% animal fat (the rest is lye). Tastes terrible to people, but not to mice.

bvtaylor
Mon, Feb-07-05, 10:00
I think this study pertaining to grehlin and leptin is more relevant and it was done on people....

http://radio.weblogs.com/0117471/2004/12/06.html#a219

Sleep as Treatment for Obesity (http://radio.weblogs.com/0117471/2004/12/06.html#a219)

http://radio.weblogs.com/0117471/images/myimages/sleepscale.jpgAn article in the Public Library of Science Medicine (PLos Medicine (http://medicine.plosjournals.org/perlserv/?request=index-html&issn=1549-1676)) by sleep researchers from Bristol University along with colleagues from Stanford and University of Wisconsin studied 1,024 volunteers from the Wisconsin Sleep Cohort Study, a population-based study of sleep disorders. The participants underwent continuous sleep monitoring, and reported on their sleep habits through questionnaires and sleep diaries. The study found that individuals who habitually slept for 5 hours were found to have 15% more ghrelin than those who slept for 8 hours. They were also found to have 15% less leptin. Ghrelin increases feelings of hunger while leptin acts to suppress appetite. Essentially, individuals who spent less than 8 hours sleeping were shown to have a greater likelihood of being heavier.