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Philip Dei
Fri, Jul-11-03, 19:14
http://groups.yahoo.com/group/DNAanthro/message/311

Philip Dei
Fri, Jul-11-03, 19:14
On Fri, 11 Jul 2003 10:21:59 -0500, Philip Deitiker
<pdeitik@bcm.tmc.edu> wrote:

>
>
>http://groups.yahoo.com/group/DNAanthro/message/311

Apparently they have revised down the MRCA for PDHA1 from
1.86 million year to 1.73 million years

I should also point out that this paper fails to account for 2
fixed xlinked loci that were included in takahata. As it
stands at this moment we have 11 xlinked loci.

6 my C/H LCA

fixed fixed .37 (Harris&Hey 2001, FIX) .41 .53 .58 .74 (Xq21.2
study) .93
2.28
3.35
4.07 (Harris&Hey 1999, PDHA1)

According the the Paper the MRCA based on xlink is higher than
expected for mtDNA.

The expectation based on mtDNA popsize of 10560 (for 6 my
C/H LCA, 8800 for 5)

655 kya, however the mean is considerably higher because of
the scewed distribution of expecteds.

752 kya

The current mean is right on the expected for MRCAs. However I
have to condition this argument the two fixed loci MRCA to
before 115 kya, thus the mean of the above is around

770 kya

about 2% higher than expected.